Searchable abstracts of presentations at key conferences in endocrinology

ea0062p16 | Poster Presentations | EU2019

Solitary myofibroblastoma of the forearm presenting with ectopic β-human Chorionic Gonadotrophin production.

Rehman Shoib , Dhatariya Ketan

A 57-year-old woman was referred due to elevated urine & serum human chorionic gonadotrophin (β-hCG) concentrations found at routine pre-operative assessment. She was asymptomatic and was not pregnant. Her past history included a long standing benign 7 cm×5 cm myofibroblastic mass in her left forearm asthma, rotator cuff tear and a uterine fibroid. Her medications were cyclical norethisterone, lansoprazole, frusemide & inhalers. The left forearm mass was not ...

ea0021p335 | Steroids | SFEBES2009

Diagnostically difficult Cushing’s syndrome in a pharmacy student

Marath Haris , Dhatariya Ketan

Twenty-two years old pharmacy student was urgently referred from primary care with a history of recent weight gain of 15 kg and an elevated 24 h urinary free cortisol (UFC) of 4517 nmol/l (<330). Clinically she described increasing hirsutism, low mood, loss of libido and symptoms suggestive of proximal myopathy.Her past medical history included recurrent low impact wrist fractures, asthma, PCOS, depression and epilepsy.On exami...

ea0091wg6 | Workshop G: Disorders of appetite and weight | SFEEU2023

Post-prandial hypoglycaemia of unknown origin

Koutroukas Vaios , Dhatariya Ketan , Brooke Antonia

Introduction: α 19-year-old female patient with no past medical history presented with multiple collapses following exercise due to hypoglycaemia. From the history it transpired that she had had previous symptoms consistent with hypoglycaemia on multiple occasions, with no relation to fasting or food or a specific diurnal or nocturnal pattern. The two most severe episodes (requiring paramedic treatment) were in the recovery period from anaerobic exercise. Her body mass in...

ea0022p184 | Clinical case reports and clinical practice | ECE2010

Emergency use of etomidate in acute steroid psychosis for an adrenal cancer causing Cushing’s syndrome

Brahma Anupam , Karaczun Mark , Dhatariya Ketan

Introduction: The psychiatric consequences of inoperable Cushing’s syndrome can be difficult to manage medically. Etomidate, an imidazole derived anaesthetic agent, inhibits cortisol synthesis and may be useful in this circumstance.The case: A 57-year-old woman presented with symptoms and signs of hypercortisolism. She gave a history of recent onset intermittent right sided stabbing chest pain and worsening breathlessness.Two ...

ea0015p277 | Reproduction | SFEBES2008

Diagnostic and therapeutic implications of using calculated free testosterone in men with low-normal total testosterone levels

Chitale Sudhanshu , Sethia Krishna , Dhatariya Ketan

Materials and methodsTwenty-eight men with erectile dysfunction (ED) were investigated with TT, SHBG, albumin, fasting blood glucose, hormonal profile and a lipid profile. Free testosterone and bio-available testosterone (BAT) were calculated in all men using the calculator on the ISSAM website ( The mean age was 55...

ea0028p44 | Clinical practice/governance and case reports | SFEBES2012

Determining the utility of the 60 minute cortisol measurement in the short synacthen test

Chitale Aditi , Musonda Patrick , McGregor Alan , Dhatariya Ketan

Context: Despite the widespread use of the short synacthen test (SST), there remains no clear consensus on sampling times for the measurement of serum cortisol that best determines adrenal reserve.Objective: To establish whether there is any value in measuring serum cortisol at 60 minutes following administration of synacthen.Design and setting: Retrospective data analysis of 500 SST results measuring 0, 30 and 60 minute cortisol l...

ea0015p217 | Pituitary | SFEBES2008

The man with two concurrent pituitary tumours

Satish Artham , Gorick Sondra , Michael Powell , Dhatariya Ketan

A 43-year-old man presented with aching legs, gynaecomastia, erectile dysfunction, central obesity, and generalised hair loss. Examination confirmed these findings as well as showing him to be hypertensive at 160/100 mmHg. Routine haematology and biochemistry as well as levels of anterior pituitary hormones were normal, except for an inappropriately low TSH in the face of normal T3 and T4 levels. A pituitary MRI showed the presence of an ill defined area of reduced signal inte...

ea0028p61 | Clinical practice/governance and case reports | SFEBES2012

Referral pattern & biochemical work-up of adrenal lesions and the role of endocrinologists in managing patients undergoing surgical adrenalectomy: A single centre audit of 10 years of laparoscopic adrenalectomies

Aghili Azin , Chitale Sudhanshu , Armitage Jim , Swords Frankie , Burgess Neil , Dhatariya Ketan

Introduction: Laparoscopic adrenalectomy is the gold standard treatment for adrenal lesions. High volume centres with input from endocrinologists and urologists with a special interest in adrenal lesions may have best outcomes. Aims: To audit our practice and set standards with reference to preoperative workup and postoperative follow-up. This is a single centre, single surgeon experience of surgical adrenalectomy.Material & Method: Over a 10 year pe...

ea0094p94 | Neuroendocrinology and Pituitary | SFEBES2023

Effectiveness of Dopamine Agonists in managing Non-Functioning Pituitary Adenomas- a United Kingdom single centre retrospective review

Tam Trevor , Soong Elaine , Saada Louis , Marcus Hani , Dorward Neil , Swords Francesca , Dhatariya Ketan , Ahluwalia Rupa

Background: While dopamine agonists (DAs) are used for managing residual/recurrent non-functioning pituitary adenomas (NFPAs), guidance on patient selection, drug dosing, follow-up imaging and response criteria is lacking.Methods: Retrospective review of NFPAs treated with DAs at a U.K single centre. 14 patients on Cabergoline (November 2011-2022) were identified. Radiological response was based on 2 follow-up (FU) scans...

ea0081p345 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Understanding and improving the management of hyperosmolar hyperglycaemic state

Cuen Pan Carina Synn , Warmington Emily , Rengarajan Lakshmi , Cooper Catherine , Owen Megan , Sheikh Haaziq , Anilkumar Anjitha , Dhatariya Ketan , Webber Jonathan , Kempegowda Punith

Background: Hyperosmolar hyperglycaemic state (HHS) is an acute metabolic complication of diabetes that can lead to significant morbidity and mortality if managed incorrectly. With <1% prevalence, there is limited published literature available on HHS and most management guidelines worldwide are based solely on expert advice and opinions.Aims: To study the precipitating causes and identify baseline practises of HHS management, to highlight areas for ...