Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1426 | Thyroid (non-cancer) | ECE2017

A new strategy to estimate levothyroxine requirement after total thyroidectomy and radioiodine remnant ablation for ‘intermediate’ and ‘high’ risk differentiated thyroid cancer

Paragliola Rosa Maria , De Rosa Annapina , Di Donna Vincenzo , Papi Giampaolo , Pontecorvi Alfredo , Corsello Salvatore Maria

Introduction: The approach for initial thyroid hormone suppression in patients who undergo surgery for differentiated thyroid cancer (DTC), is based upon the risk of disease recurrence. In particular, recent American Thyroid Association guidelines suggest to maintain TSH levels between 0.1 and 0.5 mU/l and less than 0.1 mU/l for patients with ‘intermediate’ and ‘high’ risk respectively. The aim of the study is to identify the major predictive factors of LT4...

ea0049ep1341 | Thyroid (non-cancer) | ECE2017

Is Levothyroxine requirement the same for tablet and soft gel formulation in postsurgical hypothyroidism?

Di Donna Vincenzo , Paragliola Rosa Maria , De Waure Chiara , De Rosa Annapina , Papi Giampaolo , Pontecorvi Alfredo , Corsello Salvatore Maria

Background: In a previous publication we identified the major predictive factors of levothyroxine (LT4) requirement and proposed an efficient nomogram to calculate LT4 substitutive starting dose after total thyroidectomy for benign disease. The aim of this study was to assess whether the LT4 requirement differs between the tablet and the soft gel capsules formulations.Methods: One hundred and three consecutive patients su...

ea0035p1140 | Thyroid Cancer | ECE2014

Thyroglobulin before radio remnant ablation during levothyroxine withdrawal can be considered an accurate parameter of remission of differentiated thyroid cancer

Paragliola Rosa Maria , De Rosa Annapina , Di Donna Vincenzo , Locantore Pietro , Senes Paola , Prete Alessandro , Pontecorvi Alfredo , Corsello Salvatore Maria

Introduction: Differentiated thyroid cancer (DTC) is the most frequent endocrine cancer. After surgery followed, if any, by 131I radio remnant ablation (RRA), follow-up monitoring consists of neck ultrasonography (US) and measurements of thyroglobulin (Tg) levels and anti-Tg antibodies (Ac-Tg) both on levothyroxine (L-T4) therapy and after recombinant TSH (rTSH). The aim of our study is to define a cut-off of Tg before RRA (RRA-Tg) during <...

ea0032p1049 | Thyroid (non-cancer) | ECE2013

Subacute thyroiditis: unusual presentation and diagnostic troubles

Paragliola Rosa Maria , Ricciato Maria Pia , Di Donna Vincenzo , Castellino Laura , Lovicu Rosa Maria , Pontecorvi Alfredo , Corsello Salvatore Maria

A 73 years old man came to our observation for severe dysphagia and loss of weight (10 kg in 1 month). About 30 years before he had myocardial infarction and he underwent coronary artery bypass graft. One week before the first medical evaluation, patient suspended all drugs per os because he could not swallow pills and food. Thyroid function test revealed a severe hyperthyroidism (FT3 11.9 pg/ml; FT4 40 pg/ml; TSH <0.01 μU/ml). Anti-TSH ...

ea0022p729 | Steroid metabolism &amp; action | ECE2010

Testosterone levels in acute exacerbation of chronic obstructive pulmonary disease: relationship with severity indices

Mancini Antonio , Inchingolo Riccardo , Di Marco Berardino Alessandro , Di Donna Vincenzo , Leone Erika , Maria Corbo Giuseppe , Valente Salvatore , Pontecorvi Alfredo

Chronic obstructive pulmonary disease (COPD) patients could have altered endocrine function as different endocrine organs (gonads, pituitary, thyroid and pancreas) can be affected depending on the phenotype of the disease and the degree of systemic inflammation. Anabolic hormones can be involved as COPD patients can show weight loss and muscle wasting and both these conditions can modify natural history of the disease. Moreover COPD patients can frequently have acute exacerbat...

ea0016p630 | Reproduction | ECE2008

Systemic and seminal antioxidant systems in infertile men with chronic alcohol abuse

Mancini Antonio , Festa Roberto , Grande Giuseppe , Di Donna Vincenzo , Di Nicola Marco , Janiri Luigi , Tiano Luca , Paolo Littarru Gian , Pontecorvi Alfredo , Meucci Elisabetta

Oxidative stress is associated with chronic alcoholic abuse; it is also a mechanism involved in male infertility. To further investigate the relationships between these two conditions, we studied 6 patients with diagnosis of Alcohol Dependence (DSM-IV) during post-detoxification phase, who consulted our centre for infertility. We evaluated seminal parameters, hormone pattern, Total Antioxidant Capacity (TAC) and the lipophilic antioxidant Coenzyme Q10 (CoQ10), both in blood an...