Endocrine Abstracts

Background: In the presence of specific symptoms and signs, Cushing’s syndrome (CS) may be easily recognised. On the other hand, in overweight and obese patients without typical features of CS, diagnosis may be omitted. Our aim was to evaluate the prevalence of CS among overweight and obese patients.Methods: We enrolled 264 overweight and obese patients who has not overt CS clinical features between January 2012 and December 2014 at Ankara Numune Ed...

Association between idiopathic hypogonadotropic hypogonadism (IHH) and atherosclerotic disease in young males remains unclear. The present study aimed to determine the effect of improving the testosterone level on cardiovasculary (CV) risk markers in young males with IHH.Materials and methods: The study included 19 non-obese males with IHH and 17 healthy controls. The patients were treated with hCG therapy (n=8) or testosterone replacement (...

Introduction: Multifocal sclerosing thyroiditis (MST) is a recently proposed histopathological diagnosis for thyroidectomy specimens that have ≥1 radial scar-like foci. Despite the inclusion of the term thyroiditis, MST is not related to other well-known types of thyroiditis and does not have a specific clinical presentation.Case report: A 30-year-old female presented clinic due to thyrotoxicosis. She did not have any symptoms related to thyrotoxic...

Introduction: Gardner syndrome (GS) have very different extraintestinal manifestations such as include osteomas and thyroid cancers. Thyroid carcinomas associated with familial adenomatozis polyposis coli (FAP), are typically bilateral and multifocal. Our case presenting that GS included Graves’ disease (GD) and aggressive varyant of PTC.Case report: A 43-year-old men admitted to our out patient clinic for thyrotoxicosis investigation. He was compla...

Introduction: Endogenous Cushing’s syndrome (CS) results from chronic excessive cortisol secretion. Discovering the source of disease is very important, but non-invasive tests cannot always be enough at the determination of correct location. We need more novel markers for distinguishing adrenal Cushing (AC) and pituitary Cushing (CD). We conducted this study for evaluating usefullness of preoperative DHEA-S levels at differentiating AC and CD.Materi...

Introduction: Ectopic parathyroid adenomas are detected 16% of patients operated for primary hyperparathyroidism and 22% of them may be located in the anterosuperior mediastinal region. Herein we present a rare case of primary hyperparathyroidism with severe long-term elevated parathormone (PTH) levels due to ectopic parathyroid adenoma in mediastinal region that was successfully treated by using video-assisted thoracic surgery (VATS).Case report: A 38-y...

Introduction: Hypogonadism have major affect on urogenital system also have several affect on other systems like cardiovascular and skeletal systems. There are very few study conducted on markers of atherosclerosis such as flow mediated dilatation (%FMD), carotis intima-media thickness(CIMT) and adipocytokine levels in idiopatic hypogonadotropic hypogonadal(IHH) males. The aim of this study was to evaluate this atherosclerotic risk factors in adult IHH male.<p class="abste...

Introduction: Differentiated thyroid cancers (DTC) are the most frequently occuring endocrine malignancies. The factors determine the recurrences and metastases are whole body scanning (WBS) and either suppressed or stimulated thyroglobulin (sTg) levels. The aim of this study to evaluate the preablative factors predict of radioiodine remnant ablation (RRA) therapy success.Patients and methods: One hundred consecutive patients with DTC (94 papillary and s...

Aim: The aim of the present study was to evaluate the characteristic features of computerized tomography (CT) and magnetic resonance imaging (MRI) among functioning and non-functioning adrenal lesions.Materials and methods: We retrospectively reviewed the medical records of patients with adrenal mass. CT or MRI findings were available in 89 functioning and 148 non-functioning adrenal lesions (NFAL). Of the patients with functioning adrenal mass, 34 were ...

İntroduction: CNS involvement is rare in acute monocytic leukemia cases. Pituitary involvement seems much more rarely with unknown frequency. Here, we present a case of AML- M5 (FAB classification) patient with pituitary involvement.Case presentation: A 29 years old, male patient, admitted to hematology clinic with visual disturbance and poor performance status. Allogeneic hematopoietic stem cell transplantation was performed in 2010 after chemothe...