Endocrine Abstracts

BackgroundThyroid nodules with indeterminate cytology represent a therapeutic challenge. The probability of malignancy had been established between 5 and 15%, but it varies among the published data. Nowadays we have molecular tests to help in therapeutic decisions, but they are not available at all centers leaving uncertainty regarding appropriate management.Objectives– To know the percentage of malignan...

BackgroundVitamin D has shown to play a role in multiple diseases due to its skeletal and extraskeletal actions (such as immunomodulation). In this sense, vitamin D deficiency has become a worldwide health issue. Few supplementation guidelines mention calcifediol treatment, its optimal dosing and treatment duration, despite being the direct precursor of calcitriol and the biomarker of vitamin D status.Objectives<p class="abstex...

IntroductionBased on the evidence available back then, in 2015 we developed a provincial multicenter protocol for screening and follow up of no-index patients with SDHB and SDHC mutations.Objectives1. To evaluate the performance of the protocol designed for the follow-up of asymptomatic SDHB and C carriers. 2. To describe the penetrance of manifestations associated with hereditary PGL-FEO syndromes type 3 and...

Background: Vitamin D deficiency is a worldwide health issue that affects more than one billion people. Few guidelines assess optimal dosing of vitamin D in general population, and although there is no international consensus, the optimum dosing for vitamin D3 and mainly calcifediol is not known.Objective(s): To assess the efficacy of calcifediol in the treatment of vitamin D deficiency, compared with therapeutic guidelines recommendations for cholecalci...