Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep367 | Clinical case reports - Thyroid/Others | ECE2016

A case with atypical parathyroid lipoadenoma presented with severe hypercalcemia and skeletal deformities

Bilginer Cuneyt , Topaloglu Oya , Cuhaci Neslihan , Dumlu Gurkan , Yazgan Aylin Kilic , Ersoy Reyhan , Cakir Bekir

Introduction: Parathyroid lipoadenoma (PLA) is a rarely seen, benign variant of parathyroid adenoma (PA). However, PA usually consists of uniform, polygonal chief cells with a few nests of oxyphil cells, PLA consists of similar histologic features, but with an abundance of fat cells. Additionally, PLA may be functional with the secretion of parathyroid hormone (PTH) or non-functional. Here, we present a case of atypical PLA presented with severe hypercalcemia and skeletal defo...

ea0041ep378 | Clinical case reports - Thyroid/Others | ECE2016

Safely operated two patients in pregnancy with primary hyperparathyroidism

Cuhaci Neslihan , Faki Sevgul , Arpaci Dilek , Dincer Nazmiye , Dumlu Gurkan , Ersoy Reyhan , Cakir Bekir

Introduction: Primary hyperparathyroidism (pHPT) during pregnancy is rare and associated with increased morbidity for both mother and fetus. Maternal complications of pHPT include nepfhrolithiasis, pancreatitis, cardiac arrhytmias, hypertension, nausea and vomiting. pHPT is caused by a solitary adenoma in 85–90% of patients, and the curative treatment is parathyroidectomy. Here, we presented two women who have diagnosed pHPT and operated without complications in pregnancy...

ea0041ep998 | Thyroid (non-cancer) | ECE2016

Hemithyroidectomy seems to be a reasonable initial surgical approach for patients with cytologically Bethesda Category III (AUS/FLUS) thyroid nodules

Bilginer Cuneyt , Ozdemir Didem , Topaloglu Oya , Aydin Cevdet , Dumlu Gurkan , Dogan Hayriye , Ersoy Reyhan , Cakir Bekir

Introduction: Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) termed as Bethesda Category III constitute 15–30% of thyroid cytology. However, the risk of malignancy in this heterogenous category is estimated as 5–15%. The recent studies has been reported the malignancy rate in the wide range of 6–48%. This causes surgical approach variability between different centers. We aimed to evaluate the initial malignancy rate...

ea0041ep1148 | Thyroid cancer | ECE2016

Preoperative predictors of malignancy in lesions classified as BETHESDA IV

Polat Sefika Burcak , Ogmen Berna , Baser Husniye , Sungu Nuran , Dumlu Gurkan , Ersoy Reyhan , Cakir Bekir

Background: Differential diagnosis of a thyroid nodule is difficult if it is a follicular lesion. Follicular lesions include follicular adenoma (FA) or a malign neoplasm (follicular cancer (FC) or follicular variant of papillary thyroid carcinoma (FVPTC)). Cytology can’t separate benign from malignant condition in follicular lesions. Differential diagnosis is important because patients often undergo less than ideal interventions, such as a total thyroidectomy for a benign...

ea0041gp209 | Thyroid - Translational & Clinical (1) | ECE2016

Higher thyrotropin can be used as an additional risk factor in prediction of malignancy in euthyroid thyroid nodules evaluated by cytology based on Bethesda system

Baser Husniye , Topaloglu Oya , Ali Tam Abbas , Evranos Berna , Alkan Afra , Sungu Nuran , Gurkan Dumlu Ersin , Ersoy Reyhan , Cakir Bekir

Introduction: Recently, it has been suggested that thyrotropin (TSH) concentration can be used as a marker for prediction of thyroid malignancy. However, the association between the cytology results and TSH levels is not clear. In this study, we aimed to investigate the relationship between TSH levels and Bethesda categories and determine the role of TSH levels in prediction of malignancy in patients with different Bethesda categories.Methods: The data o...

ea0041ep1132 | Thyroid cancer | ECE2016

Ultrasonographic scoring index can be useful in the prediction of thyroid malignancy in subcentimeter and supracentimeter thyroid nodules

Cuhaci Neslihan , Ogmen Berna , Tam Ali , Aydin Cevdet , Topaloglu Oya , Kilic Yazgan Aylin , Dumlu Gurkan , Ersoy Reyhan , Cakir Bekir

Introduction: The increased rate of thyroid malignancy as well as incidental and subcentimeter thyroid nodules have been attributed to increasing use of high-resolution US which can detect the non-palpabl or subcentimeter (maximum diameter ≤1 cm) thyroid nodules. We aimed to evaluate the sonographic features of the tyroid nodules between ≤1 cm and > 1 cm according the histopathology results and to determine the ultrasonographical predictive factors for malignan...

ea0056ep9 | Adrenal and Neuroendocrine Tumours | ECE2018

Case report: management of a patient with malignant insulinoma

Topaloglu Oya , Sendur Mehmet Ali , Dumlu Gurkan , Yildirim Fatma , Taskaldiran Isilay , Soydal Cigdem , Ersoy Reyhan , Cakir Bekir

Introduction: Malignant insulinoma is a rare functional endocrine tumor of the pancreas. Therefore, there are few data regarding their optimal therapy and long term prognosis. Malignancy is defined by the presence of metastases, mostly in lymph nodes or the liver. Generally these patients present with severe hypoglycemia and require multiple therapies. Here, we described the management of a patient with malignant insulinoma.Case: A 41-year-old woman with...