Endocrine Abstracts

Introduction: Unexplained weight loss is a cause for concern; it might indicate an underlying condition, usualy a catabolic state. In empty sella, the progressive loss of pituitary hormone secretion is usually a slow process, with symptoms varying from one person to another and depends on the underlying cause. Usually the weight remain relatively constant or we could have several arguments for weight gain.Case report: A 57 years old man with significant ...

Background: Two prevalent and underdiagnosed endocrine disorders are primary hyperparathyroidism and Klinefelter syndrome. The main cause of primary hyperparathyroidism is parathyroid adenoma. Less commonly multiple parathyroid hyperplasia have been described with or without genetic mutations. Klinefelter syndrome could also be seen as a genetic disorder, being a chromosomal condition. Methods: We report an uncommon association, without any family histor...

Background: Subacute thyroiditis is considered a rare form of inflammatory thyroid disease, triggered by a viral infection. The prevalence is higher in women and in the middle-aged groups. The rate of subacute thyroiditis recurrence is between 1.4% and 20%, with wide discrepancies between different studies; the relapse may occur soon after de treatment or even years after, and recent studies show an HLA-dependence.Methods: We present a case report of rec...

Introduction: Chronic spontaneous urticaria (CSU) has many links to autoimmune disorders, one of a described association being with autoimmune thyroiditis. The prevalence of thyroid antibodies is as high as 50% in patients with CSU. However, the pathogenic mechanism whereby thyroid autoimmunity is link to CSU is still poorly understood.Methods: We have analysed a case series of 20 patients with chronic urticaria and elevated TPO-antibodies, that have bee...

Background: Hyponatremia in not uncommon in elderly. Common causes include medication, heart, kidney and liver diseases, digestive loses, syndrome of inappropriate anti-diuretic hormone. Hormonal imbalances are sometimes overlooked. Sudden onset after a recently invasive procedure could challenge the diagnostic.Methods: We present a case report of a severe hyponatremia diagnosed after a coronary angiogram. It is a rare case of hypopituitarism secondary t...

Introduction: Aggressive forms of papillary thyroid carcinoma are more commonly observed; anaplastic and poorly differentiated types are rarer, but have a higher death rate. The transformation from papillary to anaplastic is a rare occurrence; it is even more uncommon for a small region of well-differentiated thyroid cancer to occur alongside the anaplastic form in metastatic lymph nodes.Aim: We present a case of an aggressive form of papillary thyroid c...

Introduction: The pituitary tumors which are considered pituitary incidentalomas are accidentally discovered at pituitary scan and they associate a lack of pituitary hyper-secretion. Opposite to what generally are considered for adrenal incidentalomas, the pituitary incidentalomas are more frequent with years of life.Aim: We analyzed the incidentaloma sizes related to decades of age.Material and method: This is a retrospective stud...

Introduction: The heel quantitative ultrasound (QUS) is useful tool in the assessment of fracture risk especially if cost issues are involved. It might be helpful in follow-up the patients who will not be treated with anti-osteoporotic drugs.Aim: To present the bone evaluation (DXA) after a period of time in patients who are initially assesed by both DXA and QUS.Material and patients: This is a prospective pilot study in a group of...

Introduction: The quantitative ultrasound (QUS) is an useful tool in the evaluation of the fragility fracture risk.Aim and study design: We performed the QUS fragility fracture risk groups (valided by the golden standard DXA) by a unifactorial analyze including the bone markers.Method: The cut offs used were: SI≤59U (high risk), SI≥83U (low risk), and medium risk with SI between 59 and 83U. The QUS analyze was performed...

Background: Cushing’s syndrome (CS) is associated with a hypercoagulable state and an increased risk for acute coronary syndromes, stroke, and deep vein thrombosis (DVT).Aim: To assess the prevalence of thrombotic events in a series of patients with CS.Patients and methods: Notes of 113 patients with CS were retrospectively reviewed.Results: Instable angina was diagnosed in ten women, aged 52.1±12.2...