Endocrine Abstracts

Several observations brought reported a big frequency (12–50%) of pituitary insufficiency and abnormalities of the median line. The endocrine disorders are hypothamic origin and come along of pituitary ontogeny in more 30% of the cases. These abnormalities are associated with a defect of the embryological development of the bird nasofrontal which allows the development of various regions of the encephalon and the face. We report the observations of two boys KY 18 years ol...

Introduction: Brain metastases of thyroid carcinomas are rare (0.1–5%) according to the literature data. They generally occur in a context of metastatic spread which has a serious impact on survival. We report two cases and will review the literature data.Observations: Case 1: 57-year-old patient monitoring for papillary thyroid carcinoma in its solid form trabecular classified T4N0M1with lung metastases. Following a neurological symptoms of tonic-c...

Introduction: Papillary thyroid carcinoma (PTC) has generally good prognosis, and distant spread is rare. Common sites of distant metastasis are lung parenchyma and bone. Pleural metastasis is less common (0.6%), and most cases have been detected because of pleural effusion. Malignant pleural effusion is a poor prognostic factor among patients with PTC. We report a case of pleural metastasis of PTC proved by pleural biopsy.Case report: A 62-year-old man ...

Diet and physical activity are éssensiels in support of diabetes mellitus (DM) as well as medical treatment.Aim: Evaluate the results of diet and physical activity on anthropometric and metabolic parameters of T2DM patients untreated population and methodology. 30 newly diagnosed T2DM patients (20W and 10 M; mean age 56.23±0.96 years were placed under hygienodietetic rules. Each patient underwent a clinical examination specifying TT, BMI, and m...

Introduction: Abnormalities of midline (AML) can be isolated or to be associated to secretory pituitary abnormalities that reflect a developmental defect of the hypothalamic pituitary (HP) region.Aim: Find AML in GH deficiency (GHD) and see their relationship with the appearance of the HP region and the severity of hypopituitarism (I P).Population and methodology: 160 children (141 ♂, ♀ 19) (IGH) underwent a clinical ex...

Introduction: Multiple endocrine neoplasia (MEN) are rare including MEN1:association of pituitary, pancreatic and parathyroid tumors and MEN 2 regrouping NEM2a: medullary thyroid cancer (MTC), pheochromocytoma and parathyroid tumor and NEM2b with ganglioneuromas. They’re caused by autosomal dominant mutation: MEN1 gene (MEN 1) and RET protooncogen (MEN 2).Aim: Report the phenotypic and evolutionary characteristics of MEN.Popul...

Introduction: The ovarian tumors are benign or malignant, primary or secondary proliferative processes, cystic aspect, solid or vegetating, whose growth is not directly related to a Hormonal dysfunction. They can grow at the coating tissue, be embryonic or endocrine origin.Aim: Assess the frequency of ovarian tumors and clarify their phenotypic and evolutionary characteristics.Population and methodology: This is a retrospective stu...

The GH deficiency (GHD) may be congenital with or without cause identified or acquired secondary to organic lesion in the hypothalamic region (HH). In all cases a magnetic resonance imaging is necessary.Aim: Investigate the causes of GHD Population and methodology GHD children were followed at the department of endocrinology. In addition to clinical examination, a testing hypophysiogramme is made with glucagon/propranolol/GH testing insulin on GH/cortiso...

Introduction: The causes of short stature are various and their frequency depends on whether we consult in pediatric or endocrinology.Although endocrine pathology is involved in a little <10% of cases, its recognition is important because it leads to a specific treatment that enhances the stature prognosis.Aim: Search etiologies statural delays observed in endocrinology and assess the frequency of GH deficiency.<p class="ab...

Achondroplasia is the most common genetic causes dwarfism. Its prevalence is 1/10 000 à 30 000 birth. it is an autosomal dominant disease associated with the mutation of the receptor gene growth factor on chromosome 4p16 fibroblastes FGFR3 responsable rhizomelic dwarfism and multiple complications likely to compromise the functional and vital prognosis of patients.Aim: Find the frequency of neurological complications and identify scalability.<p ...