Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps3-25-04 | Case Reports 2 | ETA2023

Dupilumab-related graves disease: A case report

Gama Catarina , Oliveira Margarida , Antunes Carolina , Calvo Paula , Lopes Leonor , Cunha Clara , Marques Bernardo , Branco Pedro , Sequeira Duarte Joao

Introduction: Graves Disease (GD) is an autoimmune disease, in which CD4+ Th2 cells secrete interleucin-4 (IL-4) and IL-5 and activate antibody production. IL-4 has been considered a therapeutic target for treatment of immune-related diseases, by enhancing and redirecting T and B cell function. Dupilumab, a monoclonal antibody, inhibits IL-4 and IL-13 and is currently used for treatment of atopic dermatitis, nasal polyposis and asthma. There is a single case report of painless...

ea0099ep159 | Pituitary and Neuroendocrinology | ECE2024

Successful medical management of giant prolactinomas: a comprehensive case report

Monteiro Antunes Carolina , Guia Lopes Leonor , Sprovera Paula , Oliveira Margarida , Pimentel Bruna , Gama Catarina , Sousa Santos Francisco , Sequeira Duarte Joao

Introduction: Giant prolactinomas (diameter >4 cm) account for less than 5% of all prolactinomas and are usually associated with markedly elevated prolactin (PRL) levels. Despite their benign nature, these tumors can be invasive, potentially leading to mass effect symptoms in affected patients.Case Report: We report a case of a 40-year-old male admitted to the emergency department with a one-week history of headaches, right palpebral edema, and ptosi...

ea0099ep457 | Thyroid | ECE2024

Cardiovascular manifestations in a complex case of thyroid storm secondary to graves: challenges and therapeutic considerations

Oliveira Margarida , Gama Catarina , Pimentel Bruna , Calvo Paula , Antunes Carolina , Lopes Leonor , Ferreira Rute , Sequeira Duarte Joao

Introduction: Thyroid storm, a life-threatening manifestation of hyperthyroidism, presents a complex clinical challenge that demands swift and precise intervention. The heart is one of the most important target organs affected by the thyrotoxic state. Thyrotoxicosis may lead to sinus tachycardia, hypertension, tachycardiomyopathy, atrial fibrillation and heart failure.Case Presentation: A 46-year-old female presented to the emergency department with symp...

ea0099ep297 | Adrenal and Cardiovascular Endocrinology | ECE2024

A rare case of antiphospholipid syndrome presenting as primary adrenal insufficiency

Dias Gama Catarina , Oliveira Margarida , Leonor Guia Lopes Maria , Monteiro Antunes Carolina , Sprovera Paula , Pimentel Bruna , Santos Mariana , Marques Bernardo , Manuel Sequeira Duarte Joao

Introduction: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder known for recurrent arterial and venous thrombotic events. It may involve multiple organ systems, but its impact on the endocrine system is rare. However, the adrenal glands are one of the most susceptible endocrine organs to APS, due to thrombosis, leading to primary adrenal insufficiency (PAI). Most cases are diagnosed in patients with known history of APS.Case Report: We r...

ea0099ep385 | Adrenal and Cardiovascular Endocrinology | ECE2024

A case of ectopic adrenal tissue in the fallopian tube

Pimentel Bruna , Oliveira Margarida , Gama Catarina , Sprovera Paula , Monteiro Antunes Carolina , Leonor Guia Lopes Maria , Cunha Clara , Brandao Ana , Oliveira Helena , Manuel Sequeira Duarte Joao

Introduction: Ectopic adrenal tissue (EAT) occurs in less than 1% of adults, more commonly in males. It may be found anywhere along the path of embryogenic migration, usually in the kidney and retroperitoneal fat. We report a case of EAT in the fallopian tube, a particularly rare localization.Case: We present a 57-year-old female with a known medical history of nephrolithiasis and previous ectopic pregnancies. The patient was submitted to a laparoscopic ...

ea0099ep99 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Association between eating behavior and post-operative diabetes mellitus remission

Sprovera Paula , Monteiro Antunes Carolina , Leonor Guia Lopes Maria , Oliveira Margarida , Gama Catarina , Pimentel Bruna , Saraiva Catarina , Manuel Sequeira Duarte Joao

Introduction: Type 2 Diabetes Mellitus (DM2) remission after bariatric surgery can be achieved in 72% of cases. This mechanism is not fully dilucidated; however, it could be caused by the action of glucose direct deposit in the jejunum.Objective: To assess the preoperative eating behavior impact in postoperative DM2 remission.Materials and methods: A retrospective chart review among obese and type 2 diabetic patients that underwent...