Searchable abstracts of presentations at key conferences in endocrinology

ea0029p596 | Diabetes | ICEECE2012

HbA1c as a tool for the diagnosis of type 2 diabetes in 208 premenopausal women with polycystic ovary syndrome

Velling Magnussen L. , Mumm H. , Andersen M. , Glintborg D.

Objective: To study HbA1c as a tool for diagnosing diabetes and to study HbA1c as a cardiovascular risk marker in patients with polycystic ovary syndrome (PCOS).Methods: A retrospective observational study at an academic tertiary-care medical center. In total, 208 premenopausal women with PCOS participated. Patients underwent clinical evaluation (Ferriman–Gallwey score, body mass index, waist, blood pressure), hormone analyses (testosterone, sex hor...

ea0029p930 | Female Reproduction | ICEECE2012

The prevalence of endometrial hyperplasia and endometrial cancer in Danish women with PCOS or hyperandrogenism

Ravn P. , Glintborg D. , Andersen M. , Holm N. , Scledermann D.

Objective: PCOS may be associated with an increased risk of endometrial hyperplasia (EH) and endometrial cancer (EC), but substantial evidence remains to be established. We investigated the prevalence of EH and EC in a well-characterized group of women with PCOS and/or clinical/biochemical hyperandrogenism.Design: Retrospective, trans-sectional study.Setting: Out-patient clinic at the Departments of Endocrinology and Gynecology, Od...

ea0029oc16.1 | Female Reproduction Clinical | ICEECE2012

The association between birth weight and PCOS in adult life. A register-based study on 523, 757 Danish women born 1973–1991

Mumm H. , Kamper-Jorgensen M. , Nybo Andersen A. , Glintborg D. , Andersen M.

Introduction: PCOS is characterized by insulin resistance and an increased risk of type 2 diabetes.Objective: To study the association between birth weight and risk of polycystic ovary syndrome (PCOS) in adult life in Danish women born 1973–1991.Methods: Female offspring born in Denmark during 1973–1991 of Danish mothers (n=523, 757) were included and followed for a total of 4, 739, 547 person-years at risk. Inform...

ea0029p1031 | Male Reproduction | ICEECE2012

Decreased osteoprotegerin levels during testosterone therapy in ageing men were associated with changed distribution of regional fat

Glintborg D. , Frederiksen L. , Hougaard D. , Brixen K. , Rasmussen L. , Andersen M.

Objective: The cardiovascular effects of testosterone treatment are debated. Osteoprotegerin (OPG) is an independent marker of cardiovascular risk. We investigated the effect of testosterone therapy on OPG levels in ageing men with low normal bioavailable testosterone levels.Design: A randomized, double-blinded, placebo-controlled study of six months testosterone therapy (gel) in 38 men aged 60–78 years with bioavailable testosterone <7.3 nmol/l...

ea0026p120 | Female reproduction | ECE2011

Smoking is associated with increased adrenal responsiveness, decreased prolactin levels and a more adverse lipid profile in 650 Caucasian patients with polycystic ovary syndrome

Glintborg D , Mumm H , Hougaard D M , Ravn P , Andersen M

Objective: Smoking may be associated with changes in metabolic risk factors and sex hormones in PCOS.Design: Retrospective trans-sectional study.Patients: Six hundred and fifty caucasian premenopausal women with the diagnoses hirsutism or PCOS were divided according to smoking status: Non-smokers (NS-PCOS=390) and smokers (S-PCOS=260). 119 healthy women were studied as controls (NS-Control=105, S-Control=14)....