Endocrine Abstracts

Background: Multimorbidity, presence of 2 or more chronic conditions, is a growing issue for patients as well as health systems. Reported prevalence of multimorbidity in females in a UK study was 23%. Presence of an additional chronic condition adds challenges to an existing condition. The difficulties of living with polycystic ovary syndrome (PCOS) have been well described both in terms of dealing with the symptoms as well as the potential metabolic and men...

Background: Multimorbidity, presence of 2 or more chronic conditions, is a growing issue for patients as well as health systems. Reported prevalence of multimorbidity in females in a UK study was 23%. Presence of an additional chronic condition adds challenges to an existing condition. The difficulties of living with polycystic ovary syndrome (PCOS) have been well described both in terms of dealing with the symptoms as well as the potential metabolic and men...

Methodology: Polycystic ovary syndrome (PCOS) has a variety of signs and symptoms compromising different phenotypic presentations. Insulin resistance is a known association of PCOS. Despite the documented effect of ethnicity on insulin resistance, there is little known about the effect of ethnicity on the clinical presentations of PCOS. We compared the clinical presentations of white and South Asian (SA) women with PCOS.Methodology: Retrospective analysi...

Introduction: Women with PCOS share the underlying pathology of insulin resistance with diabetes, metabolic syndrome and have increased prevalence of obesity. Despite these well established risk factors data on long term cardiovascular outcomes are limited and conflicting.Methodology: Retrospective analysis of a multi-ethnic database of all women with PCOS attending one UK endocrine unit between 1988 and 2009. Cardiovascular (CV) events were identified b...

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine abnormality in women with an estimated prevalence of 6–8%. Women with PCOS have a known increased prevalence of prediabetes (30–40%), type 2 diabetes (T2DM 10%), and metabolic syndrome (40%). We determined the prevalence of recorded PCOS through a structured primary care based T2DM screening programme.Methodology: Eligibility criterion for a structured and systematic sc...

Background: Structured education programmes (SEP) have proved effective in changing illness perception and increasing physical activity (PA) in those with or at risk of diabetes. The SUCCESS–RCT was designed to test such a programme in women with polycystic ovary syndrome (PCOS).Methods: This was a single centre, randomised controlled trial in overweight and obese women with PCOS aimed at increasing their walking activity by 2000 steps/day after 12 ...