Endocrine Abstracts

Background: Type 1 diabetes mellitus (T1DM) management profoundly changed across years, with increasing emphasis on stringent glycaemic control. While it is well demonstrated that the progressive improvement of glycaemic control allows a tighter command of diabetes-related complications, the positive implications thereof on reproductive functions are still unclear. Indeed, it is well known that oligomenorrhea and amenorrhea are more frequently detected in young women with T1DM...

Introduction: The prevalence of diabetes mellitus (DM) in patients with coronavirus disease (COVID)-19 varies widely, depending on population characteristics, country, age and disease severity. Moreover, pre-existing DM seems to double the risk of both critical COVID-19 and mortality.Aim: To evaluate incidence and mortality risk of COVID-19 in a large diabetic population in Northern Italy.Methods: A retrospective, observational, bi...

Background: Screening serum calcitonin (sCT) measurement in patients with thyroid nodules is still debated. Moreover, sCt cutoffs for medullary thyroid carcinoma (MTC) are not univocally defined. Also, sensitivity of cytology by fine needle aspiration biopsy (FNAb) has been demonstrated to detect approximately half of MTCs. Ct measurement in fine-needle aspiration washout fluid (Ct-FNAb) has high sensitivity and specificity and is helpful in case of non-diagnostic cytology&#18...

Introduction: COMPASS 31 questionnaire is widely employed for screening of cardiac autonomic neuropathy (CAN) in diabetes, yet its diagnostic performance varies across studies. The aims of the study are to evaluate the relation between score of the COMPASS 31 and CAN Risk Score in type 2 diabetes (T2D); additionally, to assess its performance in diagnosing diabetic peripheral neuropathy (DPN).Methods: The study involved 68 participants with T2D (mean age...

Background: HIV is associated with decreased bone mineral density (BMD) and decreased muscle mass. Osteoporosis and sarcopenia often co-exist and their onset is multifactorial. Sex steroids play a key role in the homeostasis of bone health and body composition in HIV-uninfected men, but data in MLWH are scanty.Aim: To investigate the frequency of low BMD and sarcopenia and their relationship with gonadal function in MLWH younger than 50.<p class="abs...

Background and Aim: Potential adverse effects of metabolic surgery on skeletal integrity remains an important concern. Bone loss is common after surgery due to multiple factors including vitamin D deficiency, altered calcium metabolism, mechanical load reduction and hormonal pattern changes. It is still not clear if the effects on bone health and calcium homeostasis vary according to each surgical technique. Further, long-term data of different surgical approaches are poor. Th...