Searchable abstracts of presentations at key conferences in endocrinology

ea0032p319 | Clinical case reports - Thyroid / Others | ECE2013

Everolimus. a new therapeutic target in the metastatic neuroendocrine carcinoma

Rodriguez Jose Perez , Hernandez Tomas Martin , Hernandez Cristina , Baz David Vicente , Manzano Virginia Martin , Baldrich Alfonso Gentil , Perez Angel Sendon

Introduction: Everolimus is a drug selective inhibitor of mTOR and approved by the FDA in 2011 for treatment of neuroendocrine tumors of pancreatic origin unresectable. Our objective was to evaluate the efficacy and safety of everolimus in a patient with malignant pancreatic head insulinoma.Case: This is a 31 year old man who complains of epigastric pain, dizziness, sweating and syncope related to exercise. During admission is objectively severe hypoglyc...

ea0032p1112 | Thyroid cancer | ECE2013

Ultrasound guided enolization as a therapeutic alternative in local recurrences of papillary thyroid carcinoma

Hernandez Tomas Martin , Rodriguez Jose Perez , Rivera Natividad Gonzalez , Cuadro Alberto Torres , Garcia Clara Garcia , Manzano Virginia Martin

Introduction and objectives: Multiple surgeries are associated with many complications in the local recurrence of papillary thyroid carcinoma. Our objective is to evaluate the efficiency of the enolization in the recurrent metastatic cervical lymph nodes in patients with limited nodal disease.Material and methods: We studied 13 patients (six males and seven females) with a mean age of 43±14.4 years with papillary thyroid carcinoma intervened (total ...

ea0090ep159 | Calcium and Bone | ECE2023

Atypical parathyroid adenomas and parathyroid carcinomas: Are there any differences?

Machuca Aguado Jesus , Rodriguez de Vera Gomez Pablo , Ocampo Pablo Ferreira , Domingo Alvaro Gutierrez , Idoate Gastearena Miguel Angel , Hernandez Tomas Martin

Introduction: Parathyroid carcinoma (PC) is a very rare neoplasm, which has histopathological features different from those of atypical parathyroid adenomas (APA). However, the clinical course of both tumour types is similar, with the exception of the unusual metastases of the carcinoma. With this study we aim to identify those clinical-analytical and anatomopathological variables that allow us to differentiate PCs from APAs.Material and Methods: Retrosp...

ea0037gp.23.04 | Thyroid – diagnosis | ECE2015

Impact of antithrombotic and/or anticoagulant treatment in cytological results of thyroid fine-needle biopsy

Molina Carlos Arana , Cuadro Alberto Torres , Rivera Natividad Gonzalez , Garcia Clara Garcia , Jimenez Virginia Hernando , Ojeda Luna Florencio , Hernandez Tomas Martin

Introduction: Fine-needle aspiration biopsy (FNAB) of the thyroid gland is an accurate diagnostic test used routinely in the initial evaluation of nodular thyroid disease. A sizeable subset of patients are found to be taking antithrombotic and/or anticoagulant (AT/AC) medications. This creates a dilemma for the endocrinologist, who must weigh the risk of withholding these medications (and the associated potential benefit of diagnosis) against the perceived increased risk of ia...

ea0035p51 | Adrenal cortex | ECE2014

The adrenal venous sampling is a difficult test in the localization of the primary hyperaldosteronism

Rodriguez Jose Perez , Jimenez Virginia Hernando , Hernandez Tomas Martin , Cuadro Alberto Torres , Rivera Natividad Gonzalez , Baldrich Alfonso Gentil , Cobos Manuel Malagon

Introduction and objectives: The localization of primary hyperaldosteronism is often difficult. The coexistence of nonfunctioning adenomas is common in patients older 40 years old and small adenomas undetectable by CT could confuse with bilateral hyperplasia. The AVS is considered the ‘gold standard’ test for the location of numerous guides. We describe our experience in a clinical case of primary aldosteronism.Clinical case: We present a 58 ye...

ea0035p498 | Diabetes therapy | ECE2014

Insulin infusers: 8 years experience

Jimenez Virginia Hernando , Rodriguez Jose Perez , Olmedo Isabel Serrano , Portillo Cristobal Morales , Molina Carlos Arana , Garcia Clara Garcia , Hernandez Tomas Martin

Objective: To evaluate the response to treatment with insulin infusion pumps by the evolution of HbA1c over 8 years of experience.Methods: Observational retrospective study. We evaluated the response to treatment in 122 patients with type 1 diabetes recruited between 2004 and 2012 in our area.Results: Between 2004 and 2012, 122 pumps have been implemented (average of 17.4 pumps/year). The number decreased to only four in 2012. Pres...

ea0035p597 | Endocrine tumours and neoplasia | ECE2014

Everolimus in monotherapy as a therapeutic option in paragangliomas/pheochromocytomas

Cuadro Alberto Torres , Rodriguez Jose Perez , Tamarit Ana Albero , Hernandez Tomas Martin , Rivera Natividad Gonzalez , Zoilo Juan Jose Reina , Carrasco Fernando Henao , Merino Luis De La Cruz

Introduction: Everolimus is a drug selective inhibitor of mTOR. In 2012 a Phase 2 study* of everolimus monotherapy demonstrated modest efficacy in patients with pheochromocytomas/paragangliomas. Our objective was to evaluate the efficacy and safety of everolimus in a patient with paraganglioma. (*Phase 2 study of everolimus monotherapy in patient with nonfunctioning neuroendocrine tumor or pheochromocytomas/paraglangliomas. Do-Young Oh et al. Cancer 2012 <str...

ea0049ep569 | Diabetes complications | ECE2017

Diabetic choroidopathy and renal function

Hermosilla Antonio Manuel Garrido , Muros Mariola Mendez , Portillo Cristobal Morales , Hernandez Tomas Martin , Rivera Natividad Gonzalez , Granda Maria Jesus Diaz , de la Rua Franch Enrique Rodriguez , Sanchez Estanislao Gutierrez

Objectives: Examine the relationship between choroidal thickness (CT) and renal function tests.Methods: Cross-sectional study with 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic and ocular data were analyzed as well as the following renal function tests: microalbuminuria, microalbumin/creatinine ratio and glomerular filtration rate (CKD-EPI and MDRD-4). Choroidal thickness was measured by swept-source ocular coherence tomography...