Searchable abstracts of presentations at key conferences in endocrinology

ea0026p416 | Thyroid (non cancer) | ECE2011

N-terminal pro B type natriuretic peptide levels in thyroid dysfunctions

Baser Husniye , Baser Salih , Kirnap Nazli Gulsoy , Sakaci Murat , Gursoy Gul

Introduction: Aminoterminal pro B type natriuretic peptide (NT-pro BNP) is the inactive degradation product of pro BNP. Thyroid diseases are known to have effect on NT-pro BNP levels. In this study, we aimed to determine possible changes in NT-pro BNP levels in patients with thyroid dysfunctions.Material and method: Fifteen patients with hyperthyroidism, 8 with subclinical hyperthyroidism, 12 with hypothyroidism, 15 with subclinical hypothyroidism and 35...

ea0041ep674 | Female Reproduction | ECE2016

Pregnancy by Treatment for Graves Disease in a Patient with Primary Ovarian Failure

Evranos Berna , Polat Sefika Burcak , Baser Husniye , Bestepe Nagihan , Cakir Bekir

Introduction: Premature ovarian failure (POF) is a disorder associated with female infertility, and it affects approximately 1% of women under the age of 40 year. It is considered a multifactorial, heterogeneous condition, for which the exact underlying cause remains unclear. Associations with autoimmune diseases, environmental factors and genetic causes have been described. Herein we presented a case with POF who regained fertility after the treatment of Graves disease.<p...

ea0041ep987 | Thyroid (non-cancer) | ECE2016

Evaluation of TSH receptor antibodies and histopathological features in patients with toxic multinodular and toxic nodular goiter

Aydin Cevdet , Baser Husniye , Neslihan Cuhaci Fatma , Ozdemir Didem , Yalcin Samet , Ersoy Reyhan , Cakir Bekir

Introduction: Association between high thyrotrophin receptor antibodies (TRAb) and relapse of thyroid cancer in Graves’ patients was reported previously. In this study, we aimed to investigate possible relation between TRAb and thyroid malignancies in patients with toxic multinodular (TMNG) and toxic nodular goiter (TNG).Methods: Thyroidectomized patients with a preoperative diagnosis of TMNG, TNG and euthyroid multinodular or nodular goiter (MNG/NG...

ea0041ep988 | Thyroid (non-cancer) | ECE2016

Malignancy is associated with microcalcification and AP/T ratio in ultrasonography, but not with Hashimoto’s thyroiditis in histopathology in patients with thyroid nodules evaluated as Bethesda Category III (AUS/FLUS) in cytology

Topaloglu Oya , Baser Husniye , Cuhaci Neslihan , Sungu Nuran , Yalcin Abdussamed , Ersoy Reyhan , Cakir Bekir

Introduction: The predictors of malignancy are important for decision of appropriate management in nodules with atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS). Our aim was to determine the ultrasonographical, clinical and biochemical predictors of malignancy in these patients.Methods: A total of 427 patients with Bethesda Category III (AUS/FLUS) thyroid nodules were included in this retrospective study. We d...

ea0041ep1099 | Thyroid cancer | ECE2016

Are there any differences between demographic characteristics, preoperative ultrasonographic findings, and cytological results of patients with thyroid tumors of uncertain malignant potential and papillary thyroid carcinoma of classical and non-encapsulated follicular variants?

Baser Husniye , Topaloglu Oya , Tam Abbas Ali , Alkan Afra , Kilicarslan Aydan , Ersoy Reyhan , Cakir Bekir

Introduction: Thyroid tumors of uncertain malignant potential (TT-UMP) has been accepted as a subgroup of follicular-patterned thyroid tumors for which benignancy or malignancy cannot be assessed exactly. We aimed to evaluate demographic characteristics, ultrasound (US) findings, and cytological results of patients with TT-UMP and compare these findings with the classical variant of papillary thyroid carcinoma (CV-PTC) and non-encapsulated follicular variant of PTC (NEFV-PTC) ...

ea0041ep1108 | Thyroid cancer | ECE2016

Ultrasonographical, clinical and histopathological features of 1264 nodules with papillary thyroid carcinoma and microcarcinoma based on tumor size

Cuhaci Neslihan , Baser Husniye , Topaloglu Oya , Ozdemir Didem , Kilicarslan Aydan , Ersoy Reyhan , Cakir Bekir

Introduction: In recent years, due to the improvements in ultrasonography (US), it has become possible to gain more information about the papillary throid carcinoma (PTC) and papillary tyroid microcarcinoma (PTMC). However, whether PTC and PTMC exhibit the same ultrasonographic features and behave same features is controversial. We aimed to evaluate the patients diagnosed with PTC and PTMC in terms of clinical, ultrasonographical (US) and histopathological features and their r...

ea0041ep1114 | Thyroid cancer | ECE2016

Markers predicting the contralateral lobe involvement in patients with multifocal papillary thyroid carcinoma: An instutional case series of 914 patients

Polat Sefika Burcak , Cakir Bekir , Ogmen Berna , Baser Husniye , Cuhaci Neslihan , Aydin Cevdet , Ersoy Reyhan

Background: The characteristics of multifocal PTC remain controversial. Surgical approach to multifocal tumor changes between centers. In cases that the initial procedure was lobectomy, most clinicians would suggest for completion thyroidectomy since the risk of PTC in the contralateral lobe is significant. This study aimed to evaluate the incidence of bilateral involvement, predictive factors for bilaterality and whether or not bilaterality was related with more aggressive hi...

ea0041ep1148 | Thyroid cancer | ECE2016

Preoperative predictors of malignancy in lesions classified as BETHESDA IV

Polat Sefika Burcak , Ogmen Berna , Baser Husniye , Sungu Nuran , Dumlu Gurkan , Ersoy Reyhan , Cakir Bekir

Background: Differential diagnosis of a thyroid nodule is difficult if it is a follicular lesion. Follicular lesions include follicular adenoma (FA) or a malign neoplasm (follicular cancer (FC) or follicular variant of papillary thyroid carcinoma (FVPTC)). Cytology can’t separate benign from malignant condition in follicular lesions. Differential diagnosis is important because patients often undergo less than ideal interventions, such as a total thyroidectomy for a benign...

ea0037ep65 | Adrenal cortex | ECE2015

Urinary metanephrine levels can be spurious in the diagnosis of patients with phaeochromocytoma: preliminary results from a single centre

Topaloglu Oya , Baser Husniye , Aydin Cevdet , Dirikoc Ahmet , Ersoy Reyhan , Erel Ozcan , Cakir Bekir

Introduction: Phaeochromocytomas (PHEO) are diagnosed with classic findings and symptoms but biochemical confirmation must be made. Either urinary or plasma chatecholamines and metanephrines can be used for biochemical evaluation. Normal values rule out the diagnosis, whereas fourfold increase above the upper limit of normal confirm the diagnosis. But value of borderline or less than fourfold elevations in the diagnosis is not clear. We aimed to determine the urinary fractiona...

ea0037ep227 | Calcium and Vitamin D metabolism | ECE2015

The evaluation of oxidative status via the measurements of total oxidant status, total anti-oxidant status, ischaemia-modified albumin and oxidised-low density lipoprotein in patients with vitamin D deficiency

Baser Husniye , Can Ummugulsum , Baser Salih , Hidayetoglu Bahauddin Taha , Aslan Uysaler , Buyuktorun Ilker , Yerlikaya Fatma Humeyra

Introduction: Oxidative damage may be responsible for pathogenesis and complications of many diseases. Vitamin D deficiency has been suggested as a potential mediator of various extra-skeletal pathologies. However, there are limited data on anti-oxidant properties of vitamin D.Methods: Forty-one subjects with vitamin D deficiency and 30 healthy controls were enrolled in the study. The levels of total anti-oxidant status (TAS), total oxidant status (TOS),...