Searchable abstracts of presentations at key conferences in endocrinology

ea0067gp36 | Poster Presentations | EYES2019

Effective combined treatment of secondary hyperparathyroidism in patient on hemodialysis with ectopied parathyroid gland

Maganeva Irina S , Eremkina Anna K , Mokrysheva NG

Background: Secondary hyperparathyroidism (SHPT) is severe complication of chronic kidney disease, characterized by high serum parathyroid hormone (PTH), parathyroid gland hyperplasia, and disturbances in mineral metabolism. Effective management of SHPT includes measures to prevent hyperphosphataemia and excess PTH, to maintain serum calcium within the normal range. In dialysis patients with severe SHPT, medical treatment may fail and parathyroidectomy (PTX) is indicated for d...

ea0070aep124 | Bone and Calcium | ECE2020

«Angio Scan-01» for extraskeletal calcification assessment in patients with mineral and bone disorders in chronic kidney disease

Maganeva Irina , Volodicheva Victoria , Eremkina Anna , Aynetdinova Alina , Mokrysheva Natalia

Background: Mineral and bone disorders in chronic kidney disease (CKD-MBD) is a systemic disorder of mineral metabolism due to CKD, which is manifestedby abnormalities of calcium, phosphorus, parathormone (PTH) and vitamin D; renal osteodystrophy; extraskeletal calcification. In patients with CKD, vascular calcification occurs 10–20 years earlier than in the general population, and is highly prevalent (40–92%) in the hemodialysis population. «AngioScan-01&#187...

ea0070aep165 | Bone and Calcium | ECE2020

Primary hyperparathyroidism in multiple endocrine neoplasia type 1 (MEN-1) according to the online russian registry

Eremkina Anna , Mirnaya Svetlana , Maganeva Irina , Ajnetdinova Alina , Mokrysheva Natalia

Objective: Primary hyperparathyroidism (PHPT) is one of the most frequently diagnosed endocrine disorders. The Russian Registry of PHPT is an on-line web-based database with the aim to estimate the prevalence and main features of disease. PHPT in Multiple Endocrine Neoplasia type 1 (MEN-1) is associated with polyglandular and early involvement of parathyroid glands.Material and Methods: The database from The Russian Registry of PHPT was used for retrospe...

ea0056p236 | Calcium & Vitamin D metabolism | ECE2018

Primary hyperparathyroidism in Russian Federation: epidemiology according to the online register

Mokrysheva Nataliya , Maganeva Irina , Mirnaya Svetlana , Eremkina Anna

Objective: Primary hyperparathyroidism (PHPT) is one of the most frequently diagnosed endocrine disorders. The Russian Registry of PHPT is an on-line web-based database created in 2016 with the aim to estimate the disease prevalence and improve the quality of health care for such patients in Russian Federation. The Endocrinology Research Centre, Moscow represents The Head organization.Material and methods: We retrieved retrospective data submitted to the...

ea0090ep579 | Endocrine-related Cancer | ECE2023

Mathematical model for preoperative differential diagnosis for the parathyroid neoplasms

Krupinova Julia , Elfimova Alina , Kim Ekaterina , Eremkina Anna , Maganeva Irina , Kovaleva Elena , Mokrysheva Natalia

Backgrounds: Preoperative diagnosis of parathyroid carcinoma (PC) is critical for the determination of the scope of surgical intervention. Nowadays, specific diagnostic markers for differentiation of PC and benign tumors are unknown, and less than half of patients with PC undergo necessary en bloc surgery.Aims: To develop the instrument for preoperative diagnosis of PC.Materials and methods: A multi-center retrospective study inclu...

ea0070aep164 | Bone and Calcium | ECE2020

Increasing incidence of parathyroid carcinoma according to russian registry of the primary hyperparathyroidism

Krupinova Julia , Veretennikova Julia , Maganeva Irina , Eremkina Anna , Aynetdinova Alina , Mirnaya Svetlana , Mokrysheva Natalia

Introduction: Parathyroid carcinoma (PC) occurs in 0.005% of all malignant tumors and in less than 1% in primary hyperparathyroidism (PHPT), but recent reports indicate increasing incidence of PC.Aim: To estimate the prevalence of PC in Russia and to identify its distinctive characteristics relevant as preoperative markers.Material and methods: We conducted a retrospective study based on the online Russian Registry of 3061 patients...

ea0073aep106 | Calcium and Bone | ECE2021

Mineral and bone disorders in patients after combined kidney-pancreas or kidney transplantation

Maganeva Irina , Larina Irina , Severina Anastasia , Aynetdinova Alina , Eremkina Anna , Shamkhalova Minara , Mokrysheva Natalia

BackgroundThe kidney or kidney-pancreas transplantation corrects many of the metabolic or biochemical abnormalities associated with chronic kidney disease (CKD); however, mineral bone disease (MBD) and cardiovascular pathology remain frequent in transplant recipients. This happens especially in patients who have long history of secondary hyperparathyroidism (SHPT), as well immunosuppressive therapy plays an important role in the progression of MBD.<p...

ea0073aep128 | Calcium and Bone | ECE2021

COVID-19 and impaired calcium metabolism upon admission to the hospital

Maganeva Irina , Eremkina Anna , Bibik Ekaterina , Gorbacheva Anna , Kovaleva Elena , Aynetdinova Alina , Mokrysheva Natalia

IntroductionThere is evidence of the interaction between the main parameters of calcium-phosphorus metabolism, vitamin D and the course of a new coronavirus infection. Moreover, hypocalcemia is one of the most frequent biochemical disorders and is associated with severity of the disease, increased likelihood of hospitalization, need for mechanical ventilation, and poor prognosis in COVID-19.ObjectiveTo estima...