Searchable abstracts of presentations at key conferences in endocrinology

ea0019p242 | Pituitary | SFEBES2009

An analysis of the dose of levothyroxine in patients with central hypothyroidism

Diacono Fabrizio , Bilbao Ismene , Karavitaki Niki , Wass John AH

Background: Levothyroxine is the standard treatment for central hypothyroidism (CH). Studies assessing the optimal dose are limited and include subjects with other untreated pituitary hormone deficits, affecting the interpretation of results. A reliable comparison with the dose used in primary hypothyroidism (PH) has not been reported.Aims: To evaluate daily and body-weight-adapted levothyroxine dose (BWA-dose) in a cohort of patients with CH on appropri...

ea0019p289 | Reproduction | SFEBES2009

The importance of a specialized adult Turner Syndrome clinic

Aung Theingi , Meston Niki , Bilbao Ismene , Karavitaki Niki , Wass JAH

Background: Turner syndrome (TS) affects 1:2500 live births. Mean age of death is reported 27.9±25.5 years due to cardiovascular complications. Expert care is required for better outcome.Aim: To review data on presentation and follow-up of a large series of patients with TS attending our Adult TS clinic.Patients and methods: The records of 64 out of 72 patients were available for review.Results: About 56...

ea0037ep1273 | Clinical Cases–Thyroid/Other | ECE2015

Adrenal embolisation in severe ectopic Cushing: unusual case and extraordinary measures

Bilbao Ismene , Antunano Luisa , Olaizola Izaskun , Chacon Ana , Elias Estela , Egana Nerea , Garcia Cristina , Aranburu Maite , Yoldi Alfredo , Goena Miguel

Introduction: Pancreatic ACTHomas have a poor prognosis with severe and rapidly progressive clinical courses, influenced by hypercortisolaemia thus whenever possible, control of the cortisol levels should be obtained to reduce complications. We report the use of adrenal embolisation in a case of a life threatening paraneoplastic Cushing.Case: A 51-year-old woman with a negative past medical history complained of general weakness. Cushing’s syndrome ...

ea0035p234 | Clinical case reports Pituitary/Adrenal | ECE2014

Takotsubo cardiomyopathy triggered by pheocromocytoma crisis

Bilbao Ismene , Yoldi Alfredo , Garcia Cristina , Egana Nerea , Aranburu Maite , Luisa Antunano Maria , Olaizola Izaskun , Elias Estela , Goena Miguel

Introduction: Pheochromocytomas are a rare catecholamine secreting tumours that can mimic numerous stress-associated disorders, such as Takotsubo cardiomyopathy, or transient left ventricular apical ballooning which is brought on by an acute coronary vasospasm due to an excessive sympathetic stimulation.Case ReportA 68-year-old woman, with previous medical history of hypertension and type 2 diabetes, who was on 30 units of isuline ...

ea0070ep107 | Bone and Calcium | ECE2020

Ectopic parathyroid hormone secretion by a squamous cell carcinoma of the floor of the mouth with poor response to cinacalcet

Bilbao Ismene , Egaña Nerea , Rojo Jorge , Garcia Cristina , Olaizola Izaskun , Agea Leire , Aranburu Maite , Yoldi Alfredo , Goena Miguel

Introduction: Ectopic PTH secretion is rare, to our knowledge, with only 27 cases reported in the literature and 3, ( a tonsil, a lung and a penile) due to squamous cell carcinoma .In the few cases reported to date it appears to be more common in males and in those over the age of 60. The management of the hypercalcemia in this setting is complicated. We are aware of 2 other case reports in which cinacalcet was used in this context, but as in our case, unsuccessfully.<p cl...

ea0032p233 | Clinical case reports – Pituitary/Adrenal | ECE2013

Good response to temozolamide therapy in a man with a prolactin secreting pituitary carcinoma

Bilbao Ismene , Coca Mariano Alvarez , Garcia Cristina , Egana Nerea , Aranburu Maite , Yoldi Alfredo , Antunano Luisa , Goena Miguel

Introduction: Pituitary carcinomas are rare and their management is difficult, because they exhibit a continued growth and metastatic dissemination despite of multimodal and aggressive treatments. Temozolamide, has shown a substantial response rates in pituitary carcinomas.We report the case of a patient with a malignant prolactinoma successfully treated with temozolamide.Case report: The patient, a 62-year-old male, consulted with...

ea0032p714 | Neuroendocrinology | ECE2013

Central diabetes insipidus, as the first sign of Langerhans cell histiocytosis in an adult

Egana Nerea , Ruiz Irune , Bilbao Ismene , Aramburu Maite , Yoldi Alfredo , Garcia Cristina , Alvarez Coca Mariano , Luisa Antunano Maria , Goena Miguel

Introduction: Langerhans cell histiocytosis (LCH) is a rare granulomatous disease of unknown etiology. LCH may be localized or be a systemic disease. The diagnosis is frecuent in pediatric age. In adults, infiltration is most frecuently in bones, lungs and skin, and shows particular predilection for hypothalamo-pituitary axis.Case: A 51 years old man was referred due to polyuria of ~15 l of daily urine output. His past medical history revealed bronchiect...

ea0056p846 | Pituitary - Clinical | ECE2018

The use of colonoscopic screening in acromegaly in our everyday practice revisited: how compliant with guidelines have we been?

Bilbao Ismene , Egana Nerea , Ciriza Maite Perez de , Olaizola Izaskun , Garcia Cristina , Agea Leire , Aranburu Maite , Yoldi Alfredo , Goena Miguel

Introduction: Although it has been suggested that there is a strong association between acromegaly and premalignant colonic lesions and colon cancer, it seems that in real – life practice the adherence to ACRO colonoscopy guidelines might be lower than expected (as recently shown by M.Parolin et cols).Methods: We retrospectively reviewed the case records of the 54 patients with acromegaly seen in our center since 1994.We analyzed the findings of 27 ...

ea0081ep690 | Pituitary and Neuroendocrinology | ECE2022

Complete remision of nelson´s syndrome with cabergoline treatment

Egana Zunzunegui Nerea , Ortega Cristina Elias , Nebreda Inmaculada Venegas , Achucarro Ane Amilibia , Garay Ismene Bilbao , Calafell Maite Aramburu , Delgado Cristina Garcia , Arrieta Alfredo Yoldi

Introduction: Nelson´s Syndrome is defined as the presence of an enlarging pituitary tumor associated with elevated fasting plasma ACTH levels and hyperpigmentation in patients submitted to bilateral adrenalectomy for the treatment of Cushing´s disease. Case Report: We present a case of a 48 y/o woman who in 2015, was diagnosed of Cushing’s disease and underwent transsphenoidal adenomectomy but remission was not achieved, so the patient wa...

ea0081ep1080 | Thyroid | ECE2022

Neutropenia in hyperthyroidism

Elias Ortega Cristina , Zunzunegui Nerea Egan a , Delgado Cristina Garcia , Calafell Maria Teresa Aramburu , Alvaro Jorge Rojo , Nebreda Inmaculada Venegas , Achucarro Ane Amilibia , Garay Ismene Bilbao , Arrieta Alfredo Yoldi

Introduction: Neutropenia can indicate infectious and hematological pathology but it can also be a sign of hyperthyroidism. For this reason, it has been suggested to perform a complete blood count before starting treatment with antithyroid drugs in case of new-onset hyperthyroidism. Antithyroid drugs can cause severe neutropenia, also called agranulocytosis, when the neutrophil count is less than 500/µl. Therefore, the use of these drugs should be reconsidered if it is le...