Searchable abstracts of presentations at key conferences in endocrinology

ea0081oc9.1 | Oral Communications 9: Environmental Endocrinology | ECE2022

Higher free thyroxine associated with pfas exposure in first trimester. The odense child cohort

Jensen Richard Christian , Glintborg Dorte , Timmermann Clara Amalie Gade , Nielsen Flemming , Boye Henriette , Bilenberg Niels , Madsen Jeppe Buur , Grandjean Philippe , Jensen Tina Kold , Andersen Marianne

Background: Perfluoroalkyl substances (PFAS) are endocrine disrupting chemicals, with elimination half-lives ranging from four to eight years. Experimental studies found PFAS able to interfere with thyroid hormone-binding proteins. During the first 20 weeks of gestation (GW), the fetus is reliant on placental transfer of maternal thyroid hormones, mainly free thyroxine (FT4). However, previous studies investigating associations between exposure to PFAS and thyroid hormone stat...

ea0081ep855 | Reproductive and Developmental Endocrinology | ECE2022

Maternal prolactin-levels in pregnancy and offspring body composition at 7 years. Odense Child Cohort

Pelck Hansen Freja , Grontved Anders , Jensen Richard C , D Hojsager Frederik , Brandslund Ivan , Boye Henriette , Jensen Tina Kold , Andersen Marianne , Glintborg Dorte

Background: Prolactin is associated with metabolic risk inside and outside of pregnancy. Maternal prolactin levels could be associated with offspring body composition.Aim: To investigate if maternal prolactin-levels were linked to offspring body composition at seven years of age.Design: Prospective observational cohort study (the Odense Child Cohort).Methods: Maternal fasting blood samples were assessed durin...

ea0090rc9.5 | Rapid Communications 9: Adrenal and Cardiovascular Endocrinology 2 | ECE2023

Higher maternal cortisol associated with lower blood pressure in offspring from 3 months to 5 years of age in the odense child cohort

Al-Jorani Hajir , Christian Jensen Richard , Jonasson Mikaela , Birukov Anna , Schmedes Anne Vibeke , Christesen Henrik Thybo , Dreyer Anja Fenger , Jensen Tina Kold , Glintborg Dorte , Jensen Boye Lagerbon , Andersen Marianne

Background: Synthetic glucocorticoid exposure in late pregnancy may be associated with higher blood pressure in offspring. We hypothesized that endogenous cortisol in pregnancy relates to offspring blood pressure (OBP).Objective: To investigate associations between maternal cortisol status in 3rd trimester pregnancy and OBP.Methods: We included 1,317 mother-child pairs from Odense Child Cohort (OCC), an observational prospective co...