Endocrine Abstracts

Background: Pituitary prolactin secretion is physiologically supressed by dopaminergic tonus from hypothalamus, which itself is under regulation by various hypothalamic releasing factors. We Disturbed dopaminergic tonus in patients with liver cirrhosis is suspected.The aim of our study was to measure prolactin levels in patients with cirrhosis and to investigate the relatioship between the severity of liver disease and other clinical and laboratory param...

There have been many discussions about testosterone role in inflammation and autoimmunity. Inflammatory bowel disease (IBD) is a chronic autoimmune disease in younger age groups. The aim ouf our study was to evaluate testosterone concentration and it’s influence on disease acitivity and the quality of life.In our cross-sectional study we measured total testosterone levels in males with IBD (Crohn’s Disease, Ulcerative colitis). Age, BMI, main c...

Background: Hyponatremia is the most common electrolyte abnormality, it increases morbidity and mortality, but it is not clear if this condition influences mortality independently of other contributing factors. The aim of our study was to assess the relative contribution of hyponatremia to in-hospital mortality and to determine predictive factors associated with hyponatremia-related mortality.Materials and methods: A database search was conducted for all...

Introduction: Impaired fertility in women with Crohn’s disease compared to healthy women seems to be a consequence of Crohn’s disease, according to older studies. However, data are not consistent, and it is not clear why could the reduced fertility occur. Influence on ovarian reserve might be one of the answers.Patients: The study group consisted of women with Crohn’s disease. The control group consisted of age and BMI matched healthy wome...