Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep335 | Clinical case reports - Thyroid/Others | ECE2016

Orbitopathy as a manifestation of Immunoglobulin-G4-related disease – case report

Zwolak Agnieszka , Dudzinska Marta , Swirska Joanna , Malicka Joanna , Daniluk Jadwiga , Tarach Jerzy S

Introduction: Immunoglobulin-G4-related disease (IgG4RD) is a multidisciplinary problem due to plasmatic cells infiltration and areas of fibrosis in the affected tissues. In IgG4RD, elevation of serum IgG4 immunoglobulins is present. Clinically, the disease is mainly manifested as: autoimmune pancreatitis, salivary gland involvement, sclerosing cholangitis, lymphadenopathy, lachrymal gland enlargement, retroperitoneal fibrosis or orbital pseudotumor. The simultaneous involveme...

ea0049ep831 | Adrenal cortex (to include Cushing's) | ECE2017

ACTH-independent subclinical Cushing’s syndrome in patient with acromegaly and adrenal incidentaloma

Kurowska Maria , Malicka Joanna , Tarach Jerzy

Introduction: It is well established that acromegaly is associated with increased risk of cancer. However, it is currently unclear whether patients with acromegaly are at increased risk of developing adrenal tumors and little is known about the association between acromegaly and adrenal adenomas. The simultaneous occurrence of preclinical Cushing’s syndrome in patients with acromegaly and adrenal adenoma is extremely rare, and to our knowledge, so far only 5 such cases ha...

ea0049ep850 | Clinical case reports - Pituitary/Adrenal | ECE2017

Temozolomide alone or in combination with bevacizumab and capecitabine in the treatment of atypical pituitary adenomas – own experience

Kurowska Maria , Malicka Joanna , Tarach Jerzy

Introduction: Atypical pituitary adenomas are tumors refractory to conventional therapy and characterized by a tendency to rapid progression and high recurrence rate. The aim of the study was to summarize our experience in treatment of atypical pituitary adenomas with temozolomide (TMZ).Material: 5 patients (3F;2M) aged 44–58 (mean 52.4±5.4) years treated in 2013–2016. We analyzed the results, tolerance and side effects of TMZ.<p class...

ea0037ep776 | Pituitary: clinical | ECE2015

High diversity of Cushing's disease in patients with corticotrophic macroadenoma

Kurowska Maria , Malicka Joanna , Tarach Jerzy S

Introduction: In 7–20% of cases, Cushing’s disease is due to ACTH-producing macroadenoma. Aim of the study was to present our observations concerning etiologic, clinical, and therapeutic diversity of Cushing’s disease in patients with macrocorticotropinomas.Material and methods: Retrospective analysis of medical records of nine patients (5F; 4M) hospitalized in 2002–2015.Results: Four of the patients (2F; 2M) we...

ea0037ep1264 | Clinical Cases–Thyroid/Other | ECE2015

Severe hyponatremia in the course of autoimmune polyglandular syndrome type 2 of atypical clinical picture

Kurowska Maria , Malicka Joanna , Jerzy , Tarach Stanislaw

Introduction: Severe hyponatremia defined as the blood sodium concentration below 115 mmol/l is rarely recognised in the course of autoimmune polyglandular syndrome type 2 (APS t.2). The aim of the paper is to present the female patient with severe hyponatremia preceding the diagnosis of APS t.2 of atypical clinical picture.Case report: A 54-year-old woman with the diagnosis of psoriasis established 10 years earlier and treated for psoriatic arthritis fr...

ea0035p227 | Clinical case reports Pituitary/Adrenal | ECE2014

Meningitis coexisting with pituitary macroadenoma: report of two cases

Malicka Joanna , Kurowska Maria , Tarach Jerzy S

Background: Meningitis coexisting with pituitary macroadenoma is rarely observed. It occurs either as a primary meningitis (primary tumor manifestation), or as a secondary meningitis (after neurosurgery or reduction of the volume of the tumor which has destroyed the sellar floor or the skull base).Objective: Case reports of two patients with the concomitance of secondary meningitis and pituitary macroadenoma.Case 1: A 36-year-old m...

ea0041ep85 | Adrenal medulla | ECE2016

Clinical review of patients with pheochromocytoma diagnosed between 2011 and 2015

Kurowska Maria , Oszywa-Chabros Anna , Malicka Joanna , Tarach Jerzy S

Introduction: WHO classification of endocrine tumors defines pheochromocytoma as a tumor arising from chromaffin cells in the adrenal medulla. Almost all pheochromocytomas produce catecholamines. An annual incidence of this tumor in the general population is estimated at 3–8 cases/million/year. 40–50% of patients with pheochromocytoma are characterized by sustained hypertension, a similar percentage – only by paroxysmal hypertension and up to 10% are normotensiv...

ea0041ep263 | Clinical case reports - Pituitary/Adrenal | ECE2016

Cushing’s disease – medical chameleon – case report of the patient with cyclic, ACTH-dependent Cushing’s syndrome due to atypical pituitary macroadenoma

Malicka Joanna , Dudzinska Marta , Kurowska Maria , Tarach Jerzy S

Introduction: ACTH-secreting macroadenomas account for about 4–10% of Cushing’s disease and are often resistant to surgical treatment and radiotherapy. The aim of the study was to present diagnostic and therapeutic difficulties in a case of cyclic recurrent ACTH-dependent Cushing’s syndrome due to atypical pituitary adenoma.Case report: 50-year-old man with visceral obesity was referred to hospital because of poor control of diabetes and h...

ea0041ep374 | Clinical case reports - Thyroid/Others | ECE2016

From Horner’s syndrome to primary hyperparathyroidism: a case report

Kurowska Maria , Malicka Joanna , Chudzinski Witold , Tarach Jerzy S.

Introduction: Horner’s syndrome represents a clinical symptom that may result from a variety of lesions both in the central and peripheral nervous system. It is a combination of ipsilateral ptosis, pupillary miosis and anisocoria, enophthalmos and facial anhydrosis induced by disruption of the sympathetic innervation of the eye anywhere along its three-neuron trail. Tumors are the most frequent causes of Horner’s syndrome.Aim: Aim of the study ...

ea0037ep736 | Pituitary: clinical | ECE2015

Persistent hyponatremia in patient with acromegaly, congestive heart failure and diabetes insipidus

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Increased production of vasopressin plays a key role in the development of fluid retention and hyponatremia in patients with decompensated heart failure. Antidiuretic hormone deficiency in the course of diabetes insipidus leads to the loss of water, dehydration and hypernatremia. The aim of the study was to present difficulties in successful treatment of hyponatremia in a patient with cardiomyopathy and heart failure, receiving desmopressin because of postoperati...