Searchable abstracts of presentations at key conferences in endocrinology

ea0029p458 | Clinical case reports - Thyroid/Others | ICEECE2012

Noonan Syndrome in adulthood: two cases reports

Azriel S. , Ezquieta B. , Martin V. , Diaz Guardiola P. , Olivar J.

Introduction: Noonan syndrome (NS) is an autosomal dominant disorder or may occur on a sporadic basis, characterized by short stature, typical face dysmorphology and congenital heart defects. NS is a clinical diagnosis. Establishing the diagnosis can be very difficult, especially in adulthood. There is a great variability in expression and the phenotype become less pronounced with increasing age. The scoring system of Van der Burgt et al. has been devised to help the di...

ea0029p1260 | Obesity | ICEECE2012

Usefulness of preoperativee exenatide in control of risk factors for bariatric surgery on type 2 diabetic patients with morbid obesity

Martin-Hernandez T. , Clara G. , Gonzalez N. , Martin V. , Torres A. , Gentil A. , Morales A.

Introduction: The aim of this study was to evaluate effects on glycemic control, body weight and cardiovascular risk factors (BP, lipids and Epworth sleepiness scale) in diabetic patients with morbid obesity treated with exenatide.Material and methods: We studied consecutively 21 T2DM patients, all of them treated with metformin full dosage and insufficient metabolic control referred to our clinic for preoperative control of bariatric surgery. Twelve of ...

ea0029p1815 | Thyroid cancer | ICEECE2012

Calcitonin levels in washout of cytology needle on thyroid nodule without suspicion of medullary thyroid carcinoma

Martin T. , Garcia C. , Gonzalez N. , Sanchez P. , Barco A. , Martin V. , Sendon A.

Introduction: We study the calcitonin levels measurement in the washout of FNAB needles after sampling each thyroid nodule (FNAB-CT) as an approach to calcitonin normal value in them and distinguish of MTC and to correlate with serum CT (sCT) and cytology FNAB.Material & Methods: 109 consecutive subjects (mean age 53.7±13.4, range 18–85 yr, 79.8% females, 27.5% smokers, 18.3% autoimmune thyroid disease) initially no suspicious for MTC who u...

ea0063p1022 | Interdisciplinary Endocrinology 2 | ECE2019

Influence of type 2 diabetes on androgen levels in women with Alzheimer’s disease

Vaňkova Marketa , Vacinova Gabriela , Hill Martin , Včelak Josef , Vejražkova Daniela , Bendlova Běla

Introduction: Alzheimer’s disease (AD) is a neurodegenerative disease that is manifested by progressive loss of cognitive function. Neuroactive steroids and their metabolites have an important regulatory role in the nervous system, affect neuronal plasticity, response to stress, learning and memory and have a neuroprotective effect. One of the not fully elucidated risk factors for AD is impaired glucose tolerance/type 2 diabetes (T2D). It is well known that lower androgen...

ea0070aep372 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

The effect of SNP (rs174537) in FADS1 gene on fatty acid composition in serum lipids

Metelcová Tereza , Vaňková Markéta , Zamrazilová Hana , Hovhannisyan Milena , Tvrzická Eva , Staňková Barbora , Hill Martin , Včelák Josef , Kunešová Marie

Background: Fatty acid desaturase 1 (FADS1) gene controls the fatty acid metabolism pathway in the human body (Sergeant et al., 2012). Single nucleotide polymorphism (SNP) in FADS1 gene and percentage of polyunsaturated fatty acids inserum lipids was associated (Klingel et al., 2018). Genetically predisposition to higher plasma arachidonic and stearic acid levels were associated with incidence oflarge-artery stroke and venous thromboembolism...