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ea0081ep152 | Calcium and Bone | ECE2022

Teriparatide for hypoparathyroidism after bariatric surgery

Maggio Ettore , Morgante Cesare , Ramunno Vittoria , Corsello Andrea , Cera Gianluca , Pontecorvi Alfredo , Corsello Salvatore Maria

Background: Hypoparathyroidism is an endocrine disorder characterized by hypocalcemia due to low levels of parathyroid hormone (PTH). Activated vitamin D (calcitriol) and calcium supplementation may be difficult in patients with malabsorption, as calcium requires an acid environment to dissolve. In this setting, subcutaneous administration of PTH analogues may be effective in reducing the dosage of oral calcium and vitamin D supplementation.Case report: ...

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ea0075m03 | Metabolic Bone | EYES2021

Management of a rare life-threatening parathyroid carcinoma

Zelano Lorenzo , Maggio Ettore , Veleno Miriam , Mura Chiara , Morgante Cesare , Antonio Rota Carlo , Pontecorvi Alfredo

Background: Parathyroid carcinoma (PC) is rare, usually presenting with hyperparathyroidism and severe hypercalcemia. A standardized diagnostic, prognostic and therapeutic approach has not been provided yet and TNM staging algorithm is not universally accepted. Surgery is the first-choice treatment and is the only effective therapy to control hypercalcaemia. Chemo- or radio-therapy, local treatments or novel drugs should be reserved to selected cases.Cas...

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ea0075m13 | Metabolic Bone | EYES2021

Hypoparathyroidism after total thyroidectomy in a woman who underwent to bariatric surgery: A case report

Maggio Ettore , Veleno Miriam , Rossi Laura , Novizio Roberto , Emanuele Rizzo Gaetano , Morgante Cesare , Locantore Pietro

Background: Hypoparathyroidism (HypoPT) is characterized by low calcium and parathyroid hormone (PTH), often secondary to thyroid surgery. Treatment consists in activated vitamin D and calcium supplementation. Such treatment may be difficult in patients with malabsorption as calcium usually requires an acid environmental to dissolve, while calcitriol needs an intact intestine for a full absorption.Case report: A 36-year old woman had a history of sleeve ...

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ea0075p05 | Pituitary and neuroendocrinology | EYES2021

A rare case of gonadotroph adenoma in a young woman

Veleno Miriam , Maggio Ettore , Morgante Cesare , Novizio Roberto , Laura Leo Maria , Policola Caterina , Locantore Pietro , Pontecorvi Alfredo

Background: Functioning gonadotroph adenomas (GA) account for 20 to 25% of all pituitary adenomas. Clinical presentation consists in multiple ovarian follicles and cysts, higher estradiol level and endometrial hyperplasia. The treatment of choice is transphenoidal tumor resection.Case Presentation: A 40 year old woman presented with abdominal pain and menstrual cycle dysfunctions. Hormonal evaluation showed: FSH:13.8 mU/ml, estradiol:1549 pg/ml, PRL:81.7...

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ea0075t04 | Thyroid | EYES2021

Management of Hyperthyroidism in Pregnancy: A single center experience

Morgante Cesare , Menotti Sara , Zelano Lorenzo , Veleno Miriam , Corsello Andrea , Locantore Pietro , Antonio Rota Carlo , Pontecorvi Alfredo

Background: Overt hyperthyroidism can have a negative impact on pregnancys outcome, if not correctly treated. Furthermore anti thyroid treatment are burned by possible side effects.Objectives: We describe the experience of our center in the management of endogenous hyperthyroidism in pregnancy. evaluating the effects of the disease and treatments on fetal and maternal health.Methods: We observed 36 pregnancies (4 twins and 1 ...