Endocrine Abstracts

An 22-year-old patient with a history of homozygous sickle cell disease (complicated by multiple vaso-occlusive attacks) was referred to the endocrinologist for persistent hypercalcemia for more than one year (between 2.63 and 2.82 mmol/l, N: 2.15–2.50 mmol/l), associated with hypophosphoremia (0.71 mmol/l, N: 0.75–1.39 mmol/l) and elevation of parathyroid hormone (170 ng/l, N <49 ng/l). Cervical ultrasound did not show parathyroid adenoma, but parathyroid MIBI s...

An 82-year-old woman with a history of breast carcinoma and hypertension underwent right laparoscopic adrenalectomy for a large mass (7×5 cm) of high density without contrast (>30 UH), non-secreting. Anatomapathological examination concluded to an adrenocortical adenoma without signs of malignancy: Weiss score of 2 and Ki67 <2%. Two years later, she developed polycythemia (Hb: 17.9 g/dl (N: 11.8–15.5); hematocrit: 53.5% (N: 35.3–46.1)) without involvemen...

Introduction: Hypophysitis is a rare condition corresponding to a chronic inflammation of the pituitary gland, The clinical and radiological signs are not specific and the pathogenesis remains poorly elucidated. The aim of our work is to report the clinico-radiological aspects of hypophysitis.Material and Methods: This is a retrospective descriptive study of 09 patients hospitalized in the department of Endocrinology-Diabetology-Nutrition of Mohammed-VI ...

Introduction: Cushing’s disease represents the most frequent etiology of endogenous cushing’s syndrome. It is a severe condition associated to many comorbidities and increased mortality that occurs a long-term management to optimize these patients outcomes. This study aims to describe the phosphocalcium profile and to assess the prevalence of osteporosis in patients with cushing’s disease.Materiels and Methods: Retrospective and descriptiv...

Objective: To estimate the prevalence of malnutrition in elderly patients with diabetes mellitus (DM) in hospital settings.Patients and Methods: A retrospective descriptive study of 55 patients over 65 years of age who were hospitalized in the Endocrinology Department. The diagnosis of malnutrition was established according to the criteria proposed by the HAS 2021.Results: The mean age of the elderly included was 71.4&pm;6.6 years ...

Introduction: Cushing’s disease is a rare condition that represents the most common cause of endogenous Cushing’s syndrome. Its severity is due to cardiovascular complications, with high morbi-mortality rates. This study aims to evaluate the specific features of metabolic disorders in females having Cushing’s disease and presenting a clinical hyperandrogenism.Materials and methods: Retrospective and descriptive study, including 12 female p...

Introduction: Central diabetes insipidus reflects a serious underlying pathology in children. The etiologies are dominated in pediatric population by: central nervous system (CNS) tumors and malformations, histiocytosis, postoperative, radiation, and trauma injury to the hypothalamic-pituitary region. We report in this work three observations illustrating rare etiologies of pediatric central diabetes insipidus in the endocrinology-diabetology and nutrition department of the Mo...

Introduction: Secondary or primo-secondary amenorrhea suggests central damage of the hypothalamic-pituitary axis or peripheral damage of the reproductive system. It must be carefully investigated with an essential hormonal workup to determine the etiology and initiate the appropriate treatment.Observation: We report the case of a 21-year-old patient, admitted for exploration of a primo-secondary amenorrhea associated with a pituitary tumor syndrome made ...

Introduction: Masked hypertension (MH) is a relatively recent description leading to a similar cardiovascular risk as permanent hypertension. Masked hypertension is more common among diabetic patients.Methods: This was a case-control study. We performed 24-hour ambulatory BP in 53 type 2 diabetic patients normotensive in clinical measurement. We compared both Masked Hypertension and Normotensive groups according to clinical/laboratory parameters and targ...

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. PA is a clinical syndrome characterized by the sudden onset of headache, vomiting, visual impairment and decreased consciousness in some cases. The objectives of our study are to describe its clinical, biological and imaging features as well as the management of PA in the region of Sfax.Patients and methods: It is a re...