Endocrine Abstracts

There are controversial data on the beneficial/detrimental effects on the cardiovascular as well as on the metabolic system by the sex hormone testosterone. Recent data support the hypothesis that low levels of androgens are associated with adverse cardiovascular risk factors including an atherogenic lipid profile, obesity, insulin resistance and hypertension. AMPK is a sensor of energy balance at both the cellular and whole-body level. Once activated by low energy status, it ...

Research indicates that low testosterone is associated with CAD in men. Evidence suggests that men with hypotestosteronemia and concomitant CAD may benefit from physiological testosterone replacement therapy (PTRT). The mechanism by which testosterone produces these cardio-protective effects and the role of the androgen receptor remains largely unknown. The aim of this study was to determine whether testosterone modulates atheroma formation via its classical signalling pathway...

Research indicates that low testosterone is associated with CAD in men. Evidence suggests that men with hypotestosteronemia and concomitant CAD may benefit from physiological testosterone replacement therapy (PTRT). The mechanism by which testosterone produces these cardio-protective effects and the role of the androgen receptor remains largely unknown. The aim of this study was to determine whether testosterone modulates atheroma formation via its classical signalling ...