Endocrine Abstracts

Introduction: Young people with type 1 diabetes (T1DM) face great challenges in managing their disease. Puberty poses strains on glycaemic control. Transferring from paediatric to adult diabetic services is another obstacle. The study aims to evaluate our local transition and transfer service provision and monitoring of the young people’s HbA1c control during this challenging period.Methods: T1DM patients transferred from our hospital’s paediat...

Introduction: Sensitive neuropathy is a degenerative complication of diabetes, precipitated by chronic glycemic imbalance. It is estimated that it is present in 50% of diabetics, and that it requires treatment in 10 to 20% of cases.This study aimedto assess the prevalence of sensitive neuropathy and to identify the factors associated with it in a population of patients with diabetes.Patients and Methods: This is a descriptive and a...

Aims: To assess the knowledge of diabetic patients on the health of their feetand to identify the associated factors with good knowledge, while providing podiatric advice.Methodology: It was a descriptive and analytical transversal prospective studyabout 100 diabetic patients (44 men, 56 women; age range 29–87 years). They had an evaluation of their knowledge on the diabetic foot, using a pre-established questionnaire as well as a metabolic evaluat...

Introduction: The American Diabetes Association (ADA) recommends an annual foot screening of patients podiatric risk for ulceration and amputation, to take effective preventive measures. However, the gradation of the podiatric risk remains insufficient, particularly in Tunisia, where epidemiological references remain missing. The aim of this study was to classify a population of diabetic patients according to the grade of podiatric risk by referring to the recommendations of t...

Introduction: We would like to highlight an interesting case of 12 year-old boy with GH deficiency and its diagnostic dilemma.Case report: A 12 year-old boy was referred for growth failure. Over the last 3 years, his height and weight fell to the 2nd centile from the 25th and 9th centiles respectively. His poor growth was initially attributed to his Attention Deficit Hyperactive Disorder medication which was optimised wit...

Introduction: Continuous subcutaneous insulin infusion (CSII) can improve glycaemic control and quality of life in Type 1 Diabetes patients. It is uncommon for paediatric patients to discontinue CSII and return to multiple daily insulin injections (MDI) often due to concerns regarding worsening metabolic control. However a trial off CSII is a requirement before transition to the adult clinic. We review the outcomes of those who discontinued CSII in our centre (total 248 patien...

Introduction: Recently a serious incident due to failure in rechecking blood glucose (BG) after hypoglycaemia treatment was reported in an adult inpatient. We evaluated adherence to network guidance on hypoglycaemia management in inpatients and changes in practice following an intervention based on education and system changes.Methods: In an audit (audit-1), hypoglycaemia episodes (BG level <4 mmol/l) were identified in paediatric inpatients (age &#6...

Introduction: IIH is associated with hypo and hyperthyroidism. We report a case of IIH where the likely precipitant was the treatment for hypothyroidism itself, levothyroxine, and the challenges this presents.Case: A 14-year-old girl was diagnosed with primary hypothyroidism following investigations for short stature (height 137 cm < 0.4th centile). Serum assay showed TSH 538 mU/l (0.55–4.78 mU/l), T4 0.68 pmol/l, (1.7–22.7 pmol/...

Introduction: The management of type 1 diabetes (T1D) in young children can be extremely challenging due to high insulin sensitivity, unpredictable eating and activity and difficulty recognizing symptoms of hypoglycaemia. Continuous subcutaneous insulin infusion (CSII) therapy is beneficial in managing young children, however the small insulin doses required challenge the accuracy of standard concentration (100 IU/ml) CSII.Case report and literature revi...

Background and aims: Non-alcohol fatty liver disease (NAFLD) is increasingly recognised in diabetic patients with metabolic syndrome. Patients with poorly-controlled diabetes and metabolic syndrome are likely to have significant liver inflammation leading to fibrosis. NAFLD fibrosis score (NFS) is a validated non-invasive scoring system that identifies liver fibrosis in patients with NAFLD. The aim of this study is to examine the glycaemic control in patients with or without s...