Endocrine Abstracts

Objective: Ionized calcium via calcium sensing receptors (CaSR) mediates feedback inhibition of parat hormone (PTH) secretion. The aim of this study is to evaluate the difference in PTH response during calcium infusion test (CIT), between patients with primary hyperparathyroidism (PHPT) and healthy control (HC).Methods: Study consisted of 15 patients with confirmed PHPT and parathyroid adenoma (57.20±11.38yrs) and 15 healthy subjects-HC (57.20±...

Introduction: Adrenocortical carcinoma is a rare tumor with an incidence of 1 per million per year. It occurs in two age groups: in children under 5 years old and in adults from 4th to 6th decade of life. It is potentially curable at an early stage, unfortunatelly, about 70% of these tumors are detected late. Functional carcinomas are present with about 60% with endocrine syndrom: Cushing syndrome (30%); Virilization and premature puberty (22%); Feminization (10%); Primary hyp...

Hypercholesterolemia is associated with athero-thrombotic disease, a leading cause of mortality worldwide. Advances in both dietary and pharmacological interventions contribute to prevention and treatment of modifiable risk factors.Purified soybean phytoestrogens, isoflavones genistein (GEN) and daidzein (DAI), were reported to exert moderate cholesterol-lowering effect. In this research first we studied age-related modifications in hepatic cholesterol metabolism and serum est...