Searchable abstracts of presentations at key conferences in endocrinology

ea0063ep121 | Pituitary and Neuroendocrinology | ECE2019

Delayed diagnosis of acromegaly: a two-year journey

Bitar Asma Amalia , Stojanovic Nemanja , Mlawa Gideon

Aims: To present the case of a 69-year-old female patient who was diagnosed with acromegaly two years following the initial onset of facial and acral symptoms, having already developed colonic hyperplastic polyps, one of the complications associated with acromegaly, one year prior to diagnosis.Material: Case report and literature review.Method: Acromegaly was diagnosed based on clinical suspicion, raised IGF-1 level, absence of GH ...

ea0056p636 | Clinical case reports - Thyroid/Others | ECE2018

Primary haemoglobinopathies as a cause of secondary endocrinopathies

Subramaniam Yuvanaa , Mlawa Gideon , Stojanovic Nemanja

Background: Haemoglobinopathies are inherited disorders of haemoglobin that predispose to endocrinopathies. The common ones include growth delay, hypogonadism and subsequent osteopaenia. Less commonly seen are diabetes mellitus, thyroid and adrenal disorders. Aetiology is multifactorial and includes tissue hypoxia, chronic anaemia, iron overload, high energy demand, genetic influence and malnourishment. We present three case reports which illustrate the endocrinopathies amongs...

ea0044ep46 | (1) | SFEBES2016

Management of Thyrotoxicosis with Chronic Neutropenia; Case Report

Pasha Nida , Hodson Kathryn , Vidarthyi M , Stojanovic Nemanja , Nkonge Frederick

The new patient with Thyrotoxicosis and neutropenia is not uncommon and requires focussed deliberations on avoidance of iatrogenic neutropenic injury and raises a clinical dilemma when treating patients with pre-existing neutropenia.There is a paucity of published experience on the safety of Carbimazole and Propylthiouracil in defined neutropenic Thyrotoxic patientÂ’s preparation for definitive ablative RAI therapy or thyroidectomy.<p class="abst...

ea0044ep49 | (1) | SFEBES2016

A case of Euglycaemic Diabetic Ketoacidosis in a patient treated with Canagliflozin

Hodson Katherine , Pasha Nida , Casey Edel , Yakandawala Gangani , Stojanovic Nemanja

Canagliflozin is an oral hypoglycemic agent from the novel class of Sodium Glucose co-Transporter 2 (SGLT2) inhibitors, used in the treatment of patients with Type 2 Diabetes Mellitus (T2DM). Although effective in treatment of hyperglycemia, these medications have been linked to development of diabetic ketoacidosis (DKA) in patients with T2DM. We describe the case of a patient with T2DM, who presented with severe metabolic acidosis while taking Canagliflozin.<p class="abst...

ea0073ep167 | Pituitary and Neuroendocrinology | ECE2021

Delayed diagnosis of acromegaly: a two-year journey

Asma Bitar De Zayas-Enriquez , Stojanovic Nemanja , Mlawa Gideon

AimsTo present the case of a 69 year-old female patient who was diagnosed with acromegaly two years following the initial onset of facial and acral symptoms, having already developed colonic hyperplastic polyps, one of the complications associated with acromegaly, one year prior to diagnosis.MaterialCase report and literature review.MethodAcromegaly was diagnosed ...

ea0090ep833 | Pituitary and Neuroendocrinology | ECE2023

Case Series of Cranial Diabetes Insipidus secondary to Presumed Lymphocytic Hypophysitis Presenting During Pregnancy

Sahota Shaan , Sinclair Lydia , Casey Edel , Mlawa Gideon , Otigbah Chineze , Akinlade Funmi , Pollock Jonathan , Stojanovic Nemanja

Introduction: We present two pregnant women who were referred to obstetric endocrinology service with polyuria and polydipsia. They were investigated and treated for diabetes insipidus (DI). In both cases, the underlying pathophysiology was ADH insufficiency secondary to autoimmune lymphocytic hypophysitis. There are currently no consensus guidelines on the diagnosis of DI during pregnancy. These cases highlight best practice and endorse MDT management of chronic hypopituitari...

ea0090ep873 | Pituitary and Neuroendocrinology | ECE2023

Diabetes Insipidus caused by autoimmune lymphocytic hypophysitis resulting in diagnosis and cure of Diffuse Large B-Cell Lymphoma

Sinclair Lydia , Sahota Shaan , Chawda Sanjiv , Heath Maureen , Dulley Louise , Pollock Jonathan , Clough Victoria , Stojanovic Nemanja

Introduction: Association between lymphoma and pituitary dysfunction is well documented, though most commonly through mechanism of infiltrative pituitary metastasis, or primary lymphoma of the pituitary, rather than autoimmune lymphocytic hypophysitis. Here we present a highly unusual case whereby investigation into the cause of Diabetes Insipidus with radiological features of lymphocytic hypophysitis, led to diagnosis and cure of Diffuse Large B-cell lymphoma (DLBCL). Diabete...

ea0059ep79 | Neuroendocrinology and pituitary | SFEBES2018

Atypical presentation of Pituitary Apoplexy with fevers and gradual onset of headaches -Would you miss it?

Lunda Ngandu Danny , Subramaniam Yuvanaa , Rehmani Hassan , Stojanovic Nemanja , Hossain Belayat , Mlawa Gideon

Introduction: Pituitary apoplexy is both an endocrine and a neurosurgical emergency, and can typically present with sudden onset of headaches, impaired level of consciousness, fever, visual disturbances, nausea or vomiting. Apoplexy ensues when pre-existing pituitary tumour presumably outgrows its blood supply leading to ischaemia, necrosis and haemorrhage or infarction.Case: A 31-year-old man presented to the hospital with 3 monthsÂ’ history of grad...

ea0081p540 | Adrenal and Cardiovascular Endocrinology | ECE2022

Challenges and anxiety of fluctuating normal to mild/moderate elevations of urinary catecholamines and metanephrines in clinical practice

Grant Bonnie , Emami Mohammadreza , Adam Siraj , Casey Edel , Tanday Raj , Hawkins Anna , Stojanovic Nemanja , Syed Imran , Nikookam Khash

We present a 70-year-old female who was initially referred to the endocrinology clinic for an assessment of her type 2 diabetes mellitus. She has a complex medical history including treated hypothyroidism, mastectomy for breast cancer and ongoing yearly surveillance for an excised benign lung lesion. On further questioning she acknowledged feeling generally unwell in the days prior to her appointment and had self-presented to the emergency department with undiagnosed hypertens...

ea0070ep288 | Pituitary and Neuroendocrinology | ECE2020

From visual disturbance to thyroid cancer: An unexpected journey

Barker Florence , Grant Bonnie , Stojanovic Nemanja , Hossain Belayat , Casey Edel , Hawkins Anna , Chawda Sajiv , Syed Imran , Pollock Jonathan , Pittathankal Antony , Nikookam Khash

A 28-year-old female presented to the optician with visual disturbance, lethargy and headaches, which were initially attributed to long hours of IT work. Despite a trial of eye exercises she experienced worsening colour vision and acuity in the right eye, hence a further consultation with an optometrist. Examination did not reveal a visual field defect. Visual acuity was 6/6 with 9/17 ishihara plates in the right eye and 5/6 with 17/17 ishihara plates in the left. A further re...