Searchable abstracts of presentations at key conferences in endocrinology

ea0048p14 | Poster Presentations | SFEEU2017

Clinical outcomes of bariatric surgery in a specialist centre

Elkhenini Hanaa , Slater Chris , Ammori Basil , Ammori Basil , Akhtar Khurshid , Senapati Siba , Summers Lucinda , Summers Lucinda , New John , New John , Syed Akheel Syed Akheel

Background: Bariatric surgery is the most successful treatment for patients with severe and complex obesity.Aims: To assess clinical outcomes after bariatric surgery in a specialist centre.Setting: Specialist weight management service in a university teaching hospital.Methods: We performed an observational analysis of clinical outcomes for patients who underwent bariatric surgery during the period 31st</...

ea0050p340 | Obesity and Metabolism | SFEBES2017

Vitamin D status before and after bariatric surgery during 4 years of follow-up

Fox Alistair , Syed Akheel

Background: Bariatric surgery for severe obesity can lead to micronutrient/vitamin deficiencies.Aim: To study baseline and post-surgical prevalence of vitamin D deficiency in patients undergoing bariatric surgery.Setting: University teaching hospital in North-West England.Methods: We performed an observational cohort analysis of longitudinal data on vitamin D and related parameters in patients who underwent b...

ea0050p403 | Thyroid | SFEBES2017

Use of glucocorticoids in subacute thyroiditis

Kyriacou Angelos , Syed Akheel

Background: Subacute thyroiditis is a self-limited inflammatory thyroid disorder with a triphasic clinical course of thyrotoxicosis, hypothyroidism, and return to euthyroidism. Whilst glucocorticoid (GC) treatment is advocated for managing moderate-to-severe symptoms, the ideal initiating dose and titration regime is unclear. Traditionally, doses of up to 40 mg of prednisolone have been used. More recently, to minimize adverse effects, a 15 mg initiation dose of ...

ea0050p340 | Obesity and Metabolism | SFEBES2017

Vitamin D status before and after bariatric surgery during 4 years of follow-up

Fox Alistair , Syed Akheel

Background: Bariatric surgery for severe obesity can lead to micronutrient/vitamin deficiencies.Aim: To study baseline and post-surgical prevalence of vitamin D deficiency in patients undergoing bariatric surgery.Setting: University teaching hospital in North-West England.Methods: We performed an observational cohort analysis of longitudinal data on vitamin D and related parameters in patients who underwent b...

ea0050p403 | Thyroid | SFEBES2017

Use of glucocorticoids in subacute thyroiditis

Kyriacou Angelos , Syed Akheel

Background: Subacute thyroiditis is a self-limited inflammatory thyroid disorder with a triphasic clinical course of thyrotoxicosis, hypothyroidism, and return to euthyroidism. Whilst glucocorticoid (GC) treatment is advocated for managing moderate-to-severe symptoms, the ideal initiating dose and titration regime is unclear. Traditionally, doses of up to 40 mg of prednisolone have been used. More recently, to minimize adverse effects, a 15 mg initiation dose of ...

ea0069p25 | Poster Presentations | SFENCC2020

GCM2 variant – A rare genetic cause of Familial Isolated Hyperparathyroidism

Mathew Susan , Syed Akheel

Section 1: Case history: A 46-year-old woman was referred to the Endocrinology clinic for evaluation of persistently elevated parathyroid hormone levels despite correction of previous vitamin D deficiency. She had a history of calcific tendinitis of the left shoulder and iris pigment dispersion syndrome. Notably, her mother had undergone two parathyroid surgeries for primary hyperparathyroidism with removal of three parathyroid glands, revealing multiple parathyroid adenomas a...

ea0044p243 | Thyroid | SFEBES2016

Evaluation of clinical diagnosis of Graves’ or Non-Graves’ Hyperthyroidism Compared to Gold-Standard TRAb Test

Bell Lauren , Syed Akheel

Background: TSH receptor antibody (TRAb) measurement, with a sensitivity of >97% and specificity of 100%, is considered the gold standard investigation for diagnosing GravesÂ’ disease (GD).Aim: To evaluate clinical diagnosis of GD or non- GD hyperthyroidism at a University Teaching Hospital compared to TRAb result.Methods: Electronic records of patients who had a TRAb measurement between December 2009 and October 2015 were ...

ea0038p241 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

From the bronze age to the iron age

Grecian Sheila , Adam Safwaan , Syed Akheel

A 53 year old man, without any previous medical history, presented acutely to the Accident and Emergency Department with a 5 day history of vomiting and abdominal pain on a background of weight loss, fatigue, polyuria and polydipsia for 4 weeks. On examination he was obviously tanned and thin. He was clinically dehydrated and had palpable hepatomegaly. Immediate biochemical testing revealed hyperglycaemia with a venous blood glucose of 20.7 mmol/l, a metabolic acidosis with a ...

ea0034p225 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014

Outcomes of bariatric surgery in men versus women: a matched observational cohort analysis

Kennedy-Dalby Andrew , Ammori Basil , Syed Akheel

Background: The global uptake of bariatric surgery in men, despite high prevalence of morbid obesity and associated co-morbidities, is significantly lower compared to women. It is unclear if this is due to a perception of poorer outcomes in men. AimsTo compare weight loss and metabolic outcomes in men versus women after bariatric surgery.Design and methods: We performed a retrospective, observational cohort analysis of 80 men matched to 80 women for base...

ea0031p71 | Clinical practice/governance and case reports | SFEBES2013

Bariatric surgery in a patient with melanocortin 4 receptor mutation

Elkhenini Hanaa , New John , Syed Akheel

Whilst bariatric surgery is the most effective therapy for idiopathic morbid obesity in adults, little is known about its effectiveness in patients with monogenic obesity syndromes. We report 5-year outcome of gastric bypass surgery in a young man with severe super-obesity associated with melanocortin four receptor (MC4R) mutation.A 22-year-old male with a weight of 221.6 kg and BMI 76.7 kg/m2 was referred to our centre for bariatric surgery. ...