Endocrine Abstracts

Background & aims: Impaired glucose tolerance and diabetes as well as cardiac dysfunction are known complications in homozygous beta-thalassemic transfused patients due to iron overload. We aimed to study pancreatic alpha and beta-cell function in regularly transfused patients with homozygous beta-thalassemia and to investigate if cardiac dysfunction may correlate with the development of impaired glucose metabolism.Methods: An oral glucose tolerance ...

Background and aims: It is well recognized that insulin resistance and type 2 diabetes (T2DM) are associated with an increased risk for cardiovascular disease especially in women, while the role of sex steroids is still controversial. Women with polycystic ovary syndrome (PCOS) represent a unique biological model for the study of the impact of all these factors on cardiovascular system. We aimed to evaluate the degree of low-grade inflammation and atherosclerosis in premenopau...

Vitamin D deficiency is increasingly recognized today having taken the form of a modern epidemic. Vitamin D, being synthesized in the skin under the effect of ultraviolet light has been originally thought of as occurring only in areas of the world where people are not exposed to the sun. However, it has recently been observed that vitamin D deficiency exists even in sunny areas. Recent observations suggest that vitamin D deficiency is related to significant comorbidity, specif...

Introduction: Research results from different countries show that vitamin D deficiency is a modern reality, affecting even sunny countries. Vitamin D deficiency has been related to predisposition to the development of diabetes mellitus type 2 and it may affect the secretion and action of insulin.Aim: The aim was to study the effect of vitamin D on glycaemic control in patients with diabetes mellitus type 2.Materials and methods: Th...