Searchable abstracts of presentations at key conferences in endocrinology

ea0035p684 | Male reproduction | ECE2014

The effects of improving testosterone levels on cardiovascular risk markers in young men with idiopathic hypogonadotropic hypogonadism: preliminary findings from a prospective study

Dogan Bercem Aycicek , Karakilic Ersen , Tuna Mazhar Muslum , Arduc Ayse , Berker Dilek , Guler Serdar

Association between idiopathic hypogonadotropic hypogonadism (IHH) and atherosclerotic disease in young males remains unclear. The present study aimed to determine the effect of improving the testosterone level on cardiovasculary (CV) risk markers in young males with IHH.Materials and methods: The study included 19 non-obese males with IHH and 17 healthy controls. The patients were treated with hCG therapy (n=8) or testosterone replacement (...

ea0035p991 | Thyroid (non-cancer) | ECE2014

Multifocal sclerosing thyroiditis: a case report

Guresci Servet , Dogan Bercem Aycicek , Erkilinc Gamze , Tuna Mazhar Muslum , Kulacoglu Sezer , Guler Serdar

Introduction: Multifocal sclerosing thyroiditis (MST) is a recently proposed histopathological diagnosis for thyroidectomy specimens that have ≥1 radial scar-like foci. Despite the inclusion of the term thyroiditis, MST is not related to other well-known types of thyroiditis and does not have a specific clinical presentation.Case report: A 30-year-old female presented clinic due to thyrotoxicosis. She did not have any symptoms related to thyrotoxic...

ea0035p1137 | Thyroid Cancer | ECE2014

Gardner syndrome; a case of presenting with agressive varyant papillary thyroide cancer

Basaran Mehtap Navdar , Dogan Bercem Aycicek , Tuna Mazhar Muslum , Unal Mustafa , Berker Dilek , Guler Serdar

Introduction: Gardner syndrome (GS) have very different extraintestinal manifestations such as include osteomas and thyroid cancers. Thyroid carcinomas associated with familial adenomatozis polyposis coli (FAP), are typically bilateral and multifocal. Our case presenting that GS included Graves’ disease (GD) and aggressive varyant of PTC.Case report: A 43-year-old men admitted to our out patient clinic for thyrotoxicosis investigation. He was compla...

ea0049ep56 | Adrenal cortex (to include Cushing's) | ECE2017

The frequency of incidental liver and renal masses in patients with adrenal incidentalomas

Nasiroglu Imga Narin , Tutuncu Yasemin , Unal Mustafa , Tuna Mazhar Muslum , Aycicek Bercem , Isik Serhat , Berker Dilek , Guler Serdar

Purpose: Adrenal incidentalomas (AIs) are adrenal masses, which are found on imaging studies not performed related to an adrenal problem. Hepatic incidental masses and renal incidental masses are usually seen in abdominal imaging methods. We aim to investigate the frequency and the kind of hepatic and renal incidental masses in patients with AIs.Methods: Retrospective evaluation of 381 (245 female and 136 male) AI patients and 285 (168 female and 117 mal...

ea0035p42 | Adrenal cortex | ECE2014

Could DHEA-S be a novel marker at distinguishing adrenal and pituitary Cushing?

Basaran Mehtap Navdar , Karakilic Ersen , Tuna Mazhar Muslum , Dogan Bercem Aycicek , Isik Serhat , Berker Dilek , Guler Serdar

Introduction: Endogenous Cushing’s syndrome (CS) results from chronic excessive cortisol secretion. Discovering the source of disease is very important, but non-invasive tests cannot always be enough at the determination of correct location. We need more novel markers for distinguishing adrenal Cushing (AC) and pituitary Cushing (CD). We conducted this study for evaluating usefullness of preoperative DHEA-S levels at differentiating AC and CD.Materi...

ea0035p703 | Male reproduction | ECE2014

Evaluation of adipocytokine levels and vascular reactivity in hypogonadotropic hypogonadal males

Tuna Mazhar Muslum , Dogan Bercem Aycicek , Karakilic Ersen , Isik Serhat , Yilmaz Fatma Meric , Topcuoglu Canan , Berker Dilek , Guler Serdar

Introduction: Hypogonadism have major affect on urogenital system also have several affect on other systems like cardiovascular and skeletal systems. There are very few study conducted on markers of atherosclerosis such as flow mediated dilatation (%FMD), carotis intima-media thickness(CIMT) and adipocytokine levels in idiopatic hypogonadotropic hypogonadal(IHH) males. The aim of this study was to evaluate this atherosclerotic risk factors in adult IHH male.<p class="abste...

ea0035p1130 | Thyroid Cancer | ECE2014

Evaluation of factors predict the efficacy of thyroid remnant ablation in patients with differentiated thyroid carcinoma

Imga Narin Nasiroglu , Isik Serhat , Basaran Mehtap Navdar , Dogan Bercem Aycicek , Tuna Mazhar Muslum , Unal Mustafa , Berker Dilek , Guler Serdar

Introduction: Differentiated thyroid cancers (DTC) are the most frequently occuring endocrine malignancies. The factors determine the recurrences and metastases are whole body scanning (WBS) and either suppressed or stimulated thyroglobulin (sTg) levels. The aim of this study to evaluate the preablative factors predict of radioiodine remnant ablation (RRA) therapy success.Patients and methods: One hundred consecutive patients with DTC (94 papillary and s...

ea0049ep1453 | Thyroid (non-cancer) | ECE2017

Does Preoperative Serum Neopterin Level Predict Differentiated Thyroid Carcinoma?

Tuna Mazhar Muslum , İmga Narin Nasıroğlu , Başaran Mehtap Navdar , Doğan Bercem Aycicek , Topcuoğlu Canan , Berker Dilek , Guler Serdar

Introduction: The frequency of thyroid surgery for suspected malignancy but postoperative resulted with benign pathology tends to increase in the worldwide. Therefore, additional preoperative markers are needed to prevent excessive surgery. Neopterin is a new molecule secreted by monocytes and macrophages and indicates the activation of cellular immunity. Therefore it can be used as a marker of immune activation. We aimed to evaluate the diagnostic value of serum neopterin lev...

ea0041ep10 | Adrenal cortex (to include Cushing's) | ECE2016

Computerized tomography and magnetic resonance imaging features for differentiating functioning adrenal lesions from non-functioning adrenal lesions

Koseoglu Derya , Tuna Mazhar Muslum , Imga Narin Nasiroglu , Dogan Bercem Aycicek , Basaran Mehtap Navdar , Senel Cagdas , Tuncel Altug , Berker Dilek , Guler Serdar

Aim: The aim of the present study was to evaluate the characteristic features of computerized tomography (CT) and magnetic resonance imaging (MRI) among functioning and non-functioning adrenal lesions.Materials and methods: We retrospectively reviewed the medical records of patients with adrenal mass. CT or MRI findings were available in 89 functioning and 148 non-functioning adrenal lesions (NFAL). Of the patients with functioning adrenal mass, 34 were ...

ea0037ep801 | Pituitary: clinical | ECE2015

Analysis of the aetiology of hypopituitarism: the results from double centre study

Caliskan Mustafa , Basaran Mehtap Navdar , Beysel Selvihan , Arslan Muyesser Sayki , Ucan Bekir , Tuna Mazhar Muslum , Cakal Erman , Berker Dilek Sensoz , Guler Serdar , Delibasi Tuncay

Introduction: Hypopituitarism is commonly acquired in adult life and its main causes are pituitary tumors and/or their treatments, empty sella syndrome and etc.Patients and methods: A double centre, cross-sectional database study was performed in Turkish population for last 10 years to investigate the etiology of hypopituitarism. One-hundred forty nine patients were included (53% female and 47% male) with a mean age of 47.9±15.6 years (ranging from ...