Endocrine Abstracts

Association between idiopathic hypogonadotropic hypogonadism (IHH) and atherosclerotic disease in young males remains unclear. The present study aimed to determine the effect of improving the testosterone level on cardiovasculary (CV) risk markers in young males with IHH.Materials and methods: The study included 19 non-obese males with IHH and 17 healthy controls. The patients were treated with hCG therapy (n=8) or testosterone replacement (...

Introduction: Multifocal sclerosing thyroiditis (MST) is a recently proposed histopathological diagnosis for thyroidectomy specimens that have ≥1 radial scar-like foci. Despite the inclusion of the term thyroiditis, MST is not related to other well-known types of thyroiditis and does not have a specific clinical presentation.Case report: A 30-year-old female presented clinic due to thyrotoxicosis. She did not have any symptoms related to thyrotoxic...

Introduction: Gardner syndrome (GS) have very different extraintestinal manifestations such as include osteomas and thyroid cancers. Thyroid carcinomas associated with familial adenomatozis polyposis coli (FAP), are typically bilateral and multifocal. Our case presenting that GS included Graves’ disease (GD) and aggressive varyant of PTC.Case report: A 43-year-old men admitted to our out patient clinic for thyrotoxicosis investigation. He was compla...

Purpose: Adrenal incidentalomas (AIs) are adrenal masses, which are found on imaging studies not performed related to an adrenal problem. Hepatic incidental masses and renal incidental masses are usually seen in abdominal imaging methods. We aim to investigate the frequency and the kind of hepatic and renal incidental masses in patients with AIs.Methods: Retrospective evaluation of 381 (245 female and 136 male) AI patients and 285 (168 female and 117 mal...

Introduction: Endogenous Cushing’s syndrome (CS) results from chronic excessive cortisol secretion. Discovering the source of disease is very important, but non-invasive tests cannot always be enough at the determination of correct location. We need more novel markers for distinguishing adrenal Cushing (AC) and pituitary Cushing (CD). We conducted this study for evaluating usefullness of preoperative DHEA-S levels at differentiating AC and CD.Materi...

Introduction: Hypogonadism have major affect on urogenital system also have several affect on other systems like cardiovascular and skeletal systems. There are very few study conducted on markers of atherosclerosis such as flow mediated dilatation (%FMD), carotis intima-media thickness(CIMT) and adipocytokine levels in idiopatic hypogonadotropic hypogonadal(IHH) males. The aim of this study was to evaluate this atherosclerotic risk factors in adult IHH male.<p class="abste...

Introduction: Differentiated thyroid cancers (DTC) are the most frequently occuring endocrine malignancies. The factors determine the recurrences and metastases are whole body scanning (WBS) and either suppressed or stimulated thyroglobulin (sTg) levels. The aim of this study to evaluate the preablative factors predict of radioiodine remnant ablation (RRA) therapy success.Patients and methods: One hundred consecutive patients with DTC (94 papillary and s...

Introduction: The frequency of thyroid surgery for suspected malignancy but postoperative resulted with benign pathology tends to increase in the worldwide. Therefore, additional preoperative markers are needed to prevent excessive surgery. Neopterin is a new molecule secreted by monocytes and macrophages and indicates the activation of cellular immunity. Therefore it can be used as a marker of immune activation. We aimed to evaluate the diagnostic value of serum neopterin lev...

Aim: The aim of the present study was to evaluate the characteristic features of computerized tomography (CT) and magnetic resonance imaging (MRI) among functioning and non-functioning adrenal lesions.Materials and methods: We retrospectively reviewed the medical records of patients with adrenal mass. CT or MRI findings were available in 89 functioning and 148 non-functioning adrenal lesions (NFAL). Of the patients with functioning adrenal mass, 34 were ...

Introduction: Hypopituitarism is commonly acquired in adult life and its main causes are pituitary tumors and/or their treatments, empty sella syndrome and etc.Patients and methods: A double centre, cross-sectional database study was performed in Turkish population for last 10 years to investigate the etiology of hypopituitarism. One-hundred forty nine patients were included (53% female and 47% male) with a mean age of 47.9±15.6 years (ranging from ...