Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1088 | Clinical case reports - Pituitary/Adrenal | ECE2017

Hypogonadotropic hypogonadism, functional and transitory

Roque Catarina , Serra Filipa , Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Bello Carlos , Vasconcelos Carlos

Functional hypogonadism has been described in association with acute severe medical or surgical illness, subacute recovery and chronic disease. We present a case of transitory hypogonadism manifested during a peri-surgical period. A 42-year-old patient was sent to the endocrinology clinic due to hypertension and a solitary adrenal mass. He was treated with bisoprolol and telmisartan, that he maintains until today. The evaluation favoured non-functional adenoma but during the f...

ea0049ep1452 | Thyroid (non-cancer) | ECE2017

Malignant struma ovarii and synchronous tumour of thyroid gland in the same patient: a single pathway for two different tumours?

Capitao Ricardo , Saraiva Catarina , Santos Francisco , Ferrinho Catia , Roque Catarina , Bello Carlos , Vasconcelos Carlos

Background: Struma ovarii (SO) is the presence of thyroid tissue as a major cellular component in an ovarian tumour.Case report: A 35-year-old, Caucasian female, asymptomatic and with normal physical examination was submitted to left oophorectomy due to an ovarian mass (8.2×7.0×6.0 cm) detected in routine pelvic examination. Her mother also had history of oophorectomy for an ovarian tumour and partial thyroidectomy for benign thyroid nodule. Th...

ea0041gp63 | Clinical Case Reports | ECE2016

Triple X and premature ovarian insufficiency – case report

Roque Catarina , Moniz Catarina , Vasconcelos Carlos

Introduction: Premature ovarian insufficiency is characterized by precocious depletion of ovarian follicles, associated with amenorrhea, hypoestrogenism and high gonadotropin levels. It afflicts 1% of the female population and in 5% cases it is due to X chromosome abnormalities.Case report: A 22 year old previously healthy female, presented to the Endocrinology Clinic due to amenorrhea. She had no family history of amenorrhea, her menarche was at age 11 ...

ea0037ep1068 | Thyroid (non-cancer) | ECE2015

Graves' disease and HIV infection: bad response to antithyroid drugs due to interaction with HIV therapy

Moniz Catarina , Campos Maria Jose , Vasconcelos Carlos

Graves’ disease is one of the multiple autoimmune diseases that have been reported in HIV-infected patients. With the upsurge of highly active anti-retroviral therapy (HAART) the incidence of autoimmune diseases in HIV-infected patients is increasing, especially after immune reconstitution. We present a male, 51-year-old, who started complaining with anxiety, sudoresis and palpitations. The laboratory workout revealed hyperthyroidism: TSH <0.02 μU/ml (0.46–4...

ea0056p967 | Male Reproduction | ECE2018

Erectile Dysfunction – The hidden sickness we don’t seek

Roque Catarina , Capitao Ricardo , Ferrinho Catia , Duarte Sequeira , Vasconcelos Carlos

Introduction: Erectile dysfunction (ED) is highly prevalent and negatively impacts the patient’s and the partner’s quality of life. It is a well-established red flag for ongoing neuro-vascular disease and a predictor of coronary, cerebral and peripheral arterial disease (PAD). Our aim was to document how often do clinicians investigate ED and use it as a predictor of neuro-vascular pathology to trigger a thorough revision of cardiovascular risk factors (CVRF). This a...

ea0049ep951 | Pituitary - Clinical | ECE2017

Acute presentation of cushing disease: severe hyperglycemia and refractory hypokalemia

Bello Carlos Tavares , Santos Francisco Sousa , Ferrinhos Catia , Serra Filipa Alves , Duarte Joao Sequeira , Vasconcelos Carlos

Introduction: Cushing’s syndrome (CS) is a rare disease resulting from prolonged exposure to supraphysiological levels of glucocorticoids. Cushing’s Disease is the most frequent cause of endogenous CS. This disease has a broad spectrum of clinical manifestations and is associated with an increased morbi-mortality. Diabetes Mellitus (DM) and hypokalemic alkalosis affects up to 50 and 10% of CS patients respectively. Disease onset and severity reflects the magnitude of...

ea0049ep1207 | Clinical case reports - Thyroid/Others | ECE2017

Two case reports of amiodarone induced thyroid dysfunction: thyrotoxic and myxedematous crisis

Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Roque Catarina , Bello Carlos , Limbert Clotilde , Vasconcelos Carlos

Introduction: Amiodarone is a well-established antiarrhythmic drug frequently used in tachyarrhythmias. Side effects include hypothyroidism and hyperthyroidism. Extreme cases such as myxedematous and thyrotoxic crisis are very uncommon. Here we report one case of each of these presentations.Case Report no.1: A 73-year-old woman with history of atrial fibrillation under treatment with amiodarone presented to the emergency department with headache, nausea ...

ea0049ep1311 | Thyroid (non-cancer) | ECE2017

TSH normalization and negative anti-TSH receptor antibodies – Predictive value for remission in Graves’ disease

Roque Catarina , Santos Francisco Sousa , Capitao Ricardo , Bello Carlos , Ferrinho Catia , Vasconcelos Carlos

Graves’ disease is the most common cause of hyperthyroidism in non-endemic areas and antithyroid drugs are the preferred first-line therapy in many centers. The aim of this retrospective investigation was to verify the association of remission with the achievement of normal TSH and free-T4 during the first 18 months of treatment and to compare it with negative anti-TSH-receptor antibodies at 18 months, a marker with known prognostic value. All patients diagnosed with Grav...

ea0049ep1486 | Thyroid (non-cancer) | ECE2017

Timing to repeat thyroid fine-needle aspiration after a follicular lesion of undetermined significance result - does it matter?

Santos Francisco Sousa , Ferrinho Catia , Capitao Ricardo , Duarte Joao Sequeira , Chorao Martinha , Limbert Clotilde , Vasconcelos Carlos

Introduction: Regarding thyroid nodules, in case of follicular lesion of undetermined significance (FLUS), performing repeat fine-needle aspiration (FNA) is a common follow-up strategy. It has been suggested that a waiting period of at least 3 months between FNAs would increase the diagnostic yield. Our study aims to clarify the optimal time for repeat FNA in case of an initial FLUS result.Methods: We identified retrospectively all thyroid FNA FLUS resul...

ea0041ep258 | Clinical case reports - Pituitary/Adrenal | ECE2016

Thyrotoxicosis leading to adrenal crises reveals primary bilateral adrenal lymphoma – case report

Roque Catarina , Fonseca Ricardo , Bello Carlos , Sousa Santos Francisco , Capitao Ricardo , Vasconcelos Carlos

Introduction: Amiodarone use may be associated with secondary severe organ dysfunction. Thyrotoxicosis develops in 15% cases. Primary bilateral adrenal lymphoma is a rare malignancy. If frequently presents bilaterally and with symptoms of adrenal insufficiency. Symptomatology for both conditions is nonspecific, especially in the elderly, and a high suspicion index is necessary for appropriate diagnosis.Case report: A 78 year old female presented to the e...