Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp144 | Interdisciplinary Endocrinology 1 | ECE2019

Bilateral femoral head necrosis with low dose oral corticosteroid therapy for pan-hypopituitarism

Velloso Renata , Aquino Monica , Souza Andre

Introduction: Femoral head avascular necrosis is a dangerous complication that can occur during glucocorticoid therapy, its frequency having been counted up to 40% of patients using corticoids. Even though the complete mechanism involved in this steroid-induced injury is not completely elucidated, studies have shown there’s some relation to bone remodelling, bone vasculature disfunction and apoptosis. We report here a case of femoral osteonecrosis associated to a very low...

ea0056p603 | Obesity | ECE2018

Benign symmetric lipomatosis (Madelung’s disease)

Oliveira-Filho Antonio F , Velloso Renata N , Oliveira Sofia NP , Medeiros Paula FV , Nunes Adriana B

Multiple benign symmetric lipomatosis (Madelung’s disease, Launois–Bensaude syndrome) is significantly rare disease characterised by symmetrical focal deposition of adipose tissue in the neck, upper part of the arms, back, pelvis, and thigh. Although its etiology is uncertain, it has been associated with genetic factors, mitochondrial inheritance and alcoholism. Its pathogenesis seems to include a dysfunction of cAMP and levels of catecholamines in adipocytes. This c...

ea0063p895 | Diabetes, Obesity and Metabolism 3 | ECE2019

Neuroendocrine neoplasia and obesity

Nunes Adriana , Medeiros Gertrudes M , Velloso Renata N , Gurjao Edmar C , Nunes Adriana B , Barbosa Paulo E S

Neuroendocrine neoplasia (NENs) are rare tumours that show features of neuroendocrine differentiation. Generally, NENs can be subdivides into high-grade neuroendocrine carcinomas (NECs) and low-to-intermediate grade neuroendocrine tumours (NETs). The most common Endodermal NETs’ localisations are the lungs, ileum, appendix, and rectum. Neuroectodermal NETs include medullary thyroid cancer (MTC), pheochromocytoma (PHEO), and paraganglioma (PGL). Nets are estimated to occur...

ea0049ep389 | Clinical case reports - Thyroid/Others | ECE2017

Improved xanthomas after leptin replacement short therapy in congenital lipodystrophy patient

Oliveira-Filho Antonio F , Dantas Irla A , Velloso Renata N , de Oliveira Sofia N P , Candido Diego F F , Nunes Adriana

Berardinelli-Seip syndrome is an autosomal recessive disorder characterized by generalized lipoatrophy, extreme insulin resistance with dyslipidaemia in childhood and development of diabetes and hepatic steatosis in adolescence. The metabolic derangements can be severe and lead to substantial comorbidities, including acute pancreatitis, hepatic cirrhosis, and premature cardiovascular disease. Other manifestations can include polycystic ovarian syndrome, acanthosis nigricans, a...