Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep273 | Calcium and Vitamin D metabolism | ECE2015

Bone mineral density evolution after parathyroidectomy in patients with primary hyperparathyroidism

Vicuna Alicia , Ramos-Levi Ana , Sampedro-Nunez Miguel , Campos Sandra , Zelada Magaly , Marazuela Monica

Introduction: Primary hyperparathyroidism results in increased bone resorption. The presence of osteoporosis is at present an established surgery criteria.Objective: The aim of this study was to evaluate the changes in bone mineral density (BMD) after surgery in patients with primary hyperparathyroidism.Material and methods: Retrospective study of 58 patients with primary hyperparathyroidism treated by parathyroidectomy from 2004 t...

ea0041ep1014 | Thyroid (non-cancer) | ECE2016

Is there seasonality in the month of birth of patients with autoimmune thyroid diseases?

Ramos-Levi Ana M , Serrano-Somavilla Ana , Martinez-Hernandez Rebeca , Sampedro-Nunez Miguel , Vicuna Alicia , Vitales-Noyola Marlen , Marazuela Monica

Background: Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) are common disorders with an autoimmune etiology, which are known as autoimmune thyroid diseases (AITD). A specific seasonal pattern of the month of birth has been suggested in several autoimmune disorders, supporting the hypothesis of a link between viral infections and the development of aberrant immune-regulatory mechanisms. However, there are few studies which specifically address this issue in AIT...

ea0037gp.28.09 | Endocrine tumours and neoplasia – NETS | ECE2015

Association of angiopoietin/TIE2 plasma level and VEGF system with progression in gastroenteropancreatic neuroendocrine tumors

Sampedro-Nunez Miguel , Ramos-Levi Ana , Vicuna Alicia , Campos Sandra , Serrano Ana , Rodriguez-Munoz Ana , Martinez-Hernandez Rebeca , Martin-Perez Elena , Adrados Magdalena , Marazuela Monica

Introduction: Angiopoietins (ANG) -1 and 2, their receptor TIE2, and the vascular endothelial growth factor (VEGF) are involved in the process of angiogenesis. However, their role in the pathogenesis and development of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) is not completely understood. In a previous study of 42 patients with GEP-NET, we observed an elevation of these serum markers, especially in those with metastatic disease. The objective of this study was ...

ea0037ep1059 | Thyroid (non-cancer) | ECE2015

Serum Galectins are increased in patients with Graves' disease hyperthyroidism

Ramos-Levi Ana M , Serrano Ana , Sampedro-Nunez Miguel A , Vicuna Alicia , Rodriguez-Munoz Ana , Martinez Rebeca , De la Fuente Hortensia , Marazuela Monica

Introduction: Patients with autoimmune thyroid disease (AITD) exhibit aberrant immune-regulatory mechanisms. Galectins (Gal) are a family of glycan-binding proteins, which have been involved in immune regulation. However, the association of Gal with AITD remains unknown. In this study, we evaluated serum Gal-1 and Gal-9 in patients with AITD.Methods: Peripheral blood samples from 31 patients with Graves’ disease (GD) (14 with untreated hyperthyroidi...

ea0049ep1072 | Pituitary - Clinical | ECE2017

Risk factors for progression of the surgical remnant of non-functioning pituitary adenomas in patients treated with dopamine agonists

Gonzalez Elena Fernandez , Nunez Miguel Sampedro , Levi Ana Ramos , Caon Ana Rabe , Hughet Isabel , Moreno Nerea Aguirre , Sanchez Clara Marijuan , Peris Begona Pla , Nieto Angeles Maillo , Andres Alicia Vicuna , Flores Pedro Martinez , Azpiroz Monica Marazuela

Introduction: Surgery is the treatment of choice for non-functioning pituitary adenomas (NFPA), but remnants are frequently observed. Management of these remnants include observation (OBS), radiotherapy (RT) and/or dopamine agonist (DA) therapy. In this study, we evaluate the progression-free survival (PFS) of NFPA with postoperative remnant and the potential factors involved.Methods: We performed a single-center ambispective study of a cohort of 72 pati...