Endocrine Abstracts

Introduction: In acromegalic patients, the increased mortality and morbidity are generally due to cardiovascular, metabolic, respiratory and cerebrovascular diseases, so early diagnosis and treatment of cardiovascular lesions may save lives. The aim of this study is to find out the any possible difference in terms of carotid intima media thickness (CIMT), indices of arterial stiffness, soluble CD40 ligand (sCD40L) and some echocardiographic parameters between active and inacti...

Introduction: The most common cause of diabetes insipidus is idiopathic. However, it may be also seen after metastasis to hypothalamic–pituitary region.Case: Fifty year old female patient with breast cancer was referred to our clinic with complaints of polyuria and polydipsia. Two years ago, she had diagnosed and after surgery, she has taken three cycles of cyclophosphamide+adriamycin+5-flurourasil than three cycles dosetaxel and finally seventeen c...

Objective: Acquired partial lipodystrophy (APL) is a rare disorder characterized by progressive selective fat loss. In previous studies, metabolic complications were reported to be relatively rare in APL, while they were quite common in other types of lipodystrophy syndromes. However, so far, there has been no systematic study on metabolic complications in APL.Methods: We have systematically evaluated 21 APL patients in the Turkish Lipodystrophy Study Gr...

Hypoparathyroidism is a rare endocrine disorder whose epidemiologic characteristics regarding the cause, clinical course, acute and chronic complications have not been well defined. There is also a substantial geographic variability regarding those parameters, and country-specific local data is scarce.This study was conducted to assess the baseline characteristics, including the demographics, etiologic distribution, disease severity, medications use...

Objective: Data on gender comparisons of diagnosis, management and prognostic factors in Cushing’s disease are very limited, however, there is no such a comparison in ectopic ACTH syndrome (EAS) in the literature. The aim of this study is to compare clinical and hormonal data, neuroendocrine tumor (NET) localization, treatment and survival outcomes in Cushing’s syndrome due to EAS by gender.Material-Methods: Eleven experienced centers from our ...

Objective: SAGIT, a new instrument designed for therapeutic decision, is not routinely used yet. While the medical treatment was mostly planned according to disease activity by hormonal evaluation, the therapeutic decision has tried to be standardized with the SAGIT instrument. The aim of this study is to reassess the therapeutic decisions by clinicians in the management of acromegaly according to the SAGIT instrument.Material and Method: This multicente...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessively inherited disorders that are characterised by inactivating mutations at various steps of adrenal steroidogenic pathways causing defective cortisol biosynthesis. 21-Hydroxylase enzyme deficiency (21-OHd) constitutes more than 95% of all CAH cases.Material & Methods: Medical records of patients with all forms of CAH from 19 adult endocrinology clinics located at six ...