Endocrine Abstracts

Introduction: With the increasing incidence of obesity worldwide, there is growing demand for bariatric surgery which carries its own risks. Post Bariatric hyperinsulinemic hypoglycaemia is rare but yet challenging condition to manage.Case Presentation: In this paper we are describing the case of a 54 years old female who presented with severe hypoglycaemia symptoms 10 months post her RYGB surgery. She underwent an oral glucose tolerance test through whi...

Chronic inflammation and oxidative stress have been described as crucial factors in the pathogenesis of atherosclerosis and the occurrence of cardiovascular diseases (CVD). Polyphenols are phytochemicals with established antioxidant properties, and dark chocolate (DC), a highly consumed food, is one of main food sources of polyphenols. Many human studies have suggested a lowering effect of DC on oxidized LDL levels, while its impact on high sensitivity CRP (hs-CRP) -one of the...

Background and aim: Biophenols can act as powerful antioxidants. Pomegranate (Punica granatum) provides a rich and varied source of biophenols with the most abundant being ellagitannins, tannins, anthocyanins, ellagic, and gallic acids. Recently, we have shown that pomegranate juice consumption may alleviate cardiovascular risk factors by reducing systolic and diastolic blood pressure and exercise-induced oxidative stress. The aim of study was to investigate the effec...

The triad of hypertriglyceridemia-induced acute pancreatitis with concurrent diabetic ketoacidosis (DKA) is rare in previously undiagnosed diabetic patients. Drug-induced diabetesis one of the main adverse effects of Risperidone, a second generation (atypical) class of antipsychotic used in the treatment of schizophrenia and bipolar disorder, however, Risperidone-induced diabetic ketoacidosis is rare. We are reporting a case of diabetic ketoacidosis associated with hypertrigly...

Background and Objectives: Different definitions for the metabolic syndrome (MS) exist.Established criteria for diagnosis includes: raised blood pressure, dysglycemia, dyslipidemia, and obesity, but the used thresholds differed. Individual patients with MS need to be identified to reduce future complications. We aimed to determine the characteristics of subjects identified from healthy population to have MS by NCEP-ATP III, IDF and the consensus definition by IDF and AHA/NHLBI...

Background: Through out history, pomegranate symbolizes fertility and has been postulated to enhance sexual function and drive. Recently, we have shown that pomegranate juice rich in polyphenolic antioxidants can alleviate stress and cardiovascular risk factors by reducing systolic and diastolic blood pressure and inhibiting 11βHSD1 activity. The aim of this study was to investigate whether pomegranate juice intake influences mood and salivary testosterone levels in healt...

Objective: Macronutrients such as protein and fat have been postulated to elicit post-prandial effects upon cortisol and testosterone concentrations. This pilot study was conducted to test the hypothesis that a meal high in protein content can elicit a positive effect on post-prandial cortisol levels whilst producing a negative effect on DHEA and testosterone levels. Methods: In 13 healthy female volunteers (aged between 19–29 years; BMI ranged from...

A 21-year-old gentleman, with known congenital adrenal hyperplasia (CAH) due to 21-hydroxylase-enzyme deficiency, presented to Genito Urinary Medicine clinic with dysuria. Examination of testes revealed bilateral firm lumps. Ultrasound scan showed bilateral testicular hypoechoic masses suspicious of malignancy. A second opinion ultrasound scan done at a tertiary care centre confirmed the same findings with the possibility of tumours being either seminoma or teratoma in origin....

We reviewed the outcomes of 40 patients (30F, 10M; mean age 56 years) with thyrotoxicosis who were referred for radioactive iodine treatment (RAI) via our department (catchment area of 130 000 people) over a period of 3 years (February 2004–March 2007). Twenty-three patients had Graves (GD); 6 had single toxic adenoma (STA); 11 had toxic multinodular goitre (MNG). Thirty-six patients (90%) had a preceding isotope scan, and 2 patients (5%) had previous partial thyroidectom...

There has been great interest in the effect of Glycaemic index (GI) of food on weight reduction, obesity, metabolic syndrome and general well being in women. The majority of research into GI was focussed towards improving blood glucose control in diabetes. Also, favourable changes in blood lipids and some beneficial effect in cancers have been reported. The aim of this pilot study is to investigate the impact of ingesting food with varying GI on salivary cortisol and testoster...