Endocrine Abstracts

Introduction: Malignant phaeochromocytomas are rare tumours, developed at the medulla and paraganglia. Their diagnosis is established by the presence of metastases of organs devoid of chromaffin tissue or by the appearance of neoplastic recurrence. They are characterized by a morbidity and mortality due to the effects of uncontrolled and important hypersecretion cathécolaminergique and resistance to conventional cancer treatments.Aim: Report the obs...

Introduction: Impact of suppressive therapy with LH RH analogues is more stop the premature pubertal development, reduce the acceleration of bone maturation that compromises the final size and avoid psychological disturbances caused by hormonal imbalance.Aim: To study the effects of treatment on pubertal development, bone maturation and evolution of the size during and at the end of treatment and final height in 20 patients with central precocious pubert...

Introduction: The inflammatoirs background processes, and infiltrating tumour of the pituitary stalk are rare. They are a heterogeneous group of lesions responsible of partial or global hypopituitarism.Aim: Search for thickening of the pituitary stalk aetiologies and specify the clinical aspects.Population methodology: This is a retrospective study of 24 patients with thickening of the pituitary stalk. All patients benefited from a...

Introduction: Micropenis is defined as a stretched penile length of <2.5 S.D., which can be diagnosed from birth to adolescence. It is idiopathic or associated with a chromosomal abnormality, hypogonadism, pituitary abnormality or a complex malformation syndrome. The therapeutic management of this disease should be early to get a favorable response and absence of impact objective. Clarify the clinical and etiological aspects of micropenis of patients followe...

Introduction: Neuroendocrine tumours or TNE form from cells of the endocrine and neurological system at any point in the body and are characterised by their ability to secrete hormones and express protein markers. They are often benign, but some are malignant and can easily metastasise.Objective: To describe the clinical, paraclinical and scalable of TNE endocrinology observed outside medullary carcinoma and phaeochromocytoma.Popul...

A 31-year gentleman presented with a four day history of anxiety and confusion. Over several months, he had noticed red eyes and a ‘stomach-ache’. A collateral history revealed a previous episode of confusion and concern about excessive alcohol intake. He denied any current medication. On examination, he had bilateral conjunctivitis. Investigations demonstrated severe hypercalcaemia of 3.54 mmol/l (NR 2.15–2.6 mmol/l). He was treated with intravenous fluids and ...

Introduction: Cardiac complications are one of the most important long-term adverse effects of diabetes mellitus (DM), which is usually under diagnosed, as it is frequently asymptomatic. As it seems that the control of DM in developing nations is not optimal, it can be predicted that the prevalence of cardiac complications of DM is subsequently high. We assessed the prevalence of such complications in a developing community in the north of Iran.Method: T...

Background: Obesity is increasing in prevalence in younger people, including children and adolescents. Bariatric surgery (BS) is well-established and efficacious treatment for morbid obesity in adults. BS is being performed in younger age groups more frequently.Objective: To describe outcomes of BS under the age of 25 in Emirati individuals having follow-up at Imperial College London Diabetes Centre (ICLDC).Methods: Patients recrui...

Introduction: Levothyroxine is the first choice treatment for patients with hypothyroidism However, some people would continue to have symptoms of thyroid disease despite biochemical control on levothyroxine. Others might be intolerant to levothyroxine.Aim: The aim of this audit is to evaluate UHL endocrinology practice against local and national guidelines with regards to prescribing and monitoring of liothyronine treatment in 2019.<p class="abstext...

The VHL gene is a tumor suppressor gene located on chromosome 3p25.3. Mutations in this gene prevent production of the VHL protein and as a result, cells grow and divide uncontrollably to form the tumors and cysts. Germline VHL gene mutations predispose to a variety of tumors, most commonly retinal and cerebellar haemangioblastomas, renal cell carcinoma and phaeochromocytoma. Papillary cystadenomas of the epidididymis are seen in 10–26% of men are rarely...