Endocrine Abstracts

Introduction: Hirsutism is often caused by hormonal disorders such as high levels of circulating androgens, hormonal changes related to menopause or disorders of the ovarian or adrenal gland. The aim of our study was to evaluate the clinical and etiological profile of hirsutism.Methods: A retrospective study was conducted at the endocrinology department of Rabta Hospital in Tunis including 100 patients who presented with hirsutism between January 2009 an...

Introduction: Hirsutism is described as excessive development of facial and body hair in women in androgen-dependent areas. Our aim was to determine the clinical and metabolic aspects of hirsutism and its relationship with the metabolic syndrome.Methods: We conducted a retrospective descriptive study at the endocrinology department of Rabta Hospital in Tunis. We recruited 100 women who presented with hirsutism between January 2009 and December 2020 Clini...

Introduction: Hirsutism is defined as excessive hair growth in androgen-dependent areas in women, related to an increased exposure androgen action in pilosebaceous follicles. It may be isolated, or associated to cutaneous manifestations from acne to signs of virilism. The aim of our study was to describe the therapeutic and evolutionary aspects of hirsutism.Methods: It was a retrospective study at the endocrinology department of Rabta Hospital in Tunis i...

Introduction: There is an association between Moyamoya syndrome and Graves’ disease, described primarily in Asian populations. We report a case of Moyamoya vasculopthy with stroke and hypertension associated with graves’ disease in a 15-year-old Tunisian girl.Observation: A 15-year-old girl diagnosed with Moyamoya vasculopathy was referred to the endocrinology department for hyperthyroidism. The patient had a history of recurrent stroke and hyp...

Introduction: Primary hyperparathyroidism (PHPT) is typically characterized by elevated serum calcium associated with elevated or non-suppressed levels of parathyroid hormone (PTH). These biochemical features are both known to affect the cardiovascular (CV) system. There is a conflicting debate regarding the CV manifestations of PHPT. the aim of our study is to evaluate the cardiovascular profile in patients with PHPT.Methods: We conducted a retrospectiv...

Introduction: The development of the Covid-19 pandemic infection, which started in March 2020 in Tunisia, has impacted all medical specialties. Endocrine care professionals were part of this battle, as many patients with endocrine diseases including primary hyperparathyroidism (PHPT) were also affected by the pandemic. the aim of our study was to evaluate the Impact of the Covid19 pandemic on patients with PHPT.Methods: This is a retrospective descriptiv...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by inappropriate secretion of parathyroid hormone leading to hypercalcemia. The aim of our study is to evaluate the clinical and etiological aspects of PHPT in our series.Methods: This is a retrospective descriptive study including 32 patients followed for PHPT at the endocrinology department of the military hospital of Tunisia between January 2018 and December ...

Introduction: Surgery is the only curative treatment for primary hyperparathyroidism (PHPT). However, some patients may present a persistence or a recurrence after surgical treatment. The aim of our study was to evaluate the therapeutic and evolutive aspects of PHPT after the first surgery.Methods: A retrospective study was conducted at the endocrinology department of military hospital of Tunis including 32 patients diagnosed with PHPT over a period of f...

Introduction: Classification of diabetes is challenging in some cases, especially in the presence of inaugural ketosis with a negative autoimmune laboratory test. The aim of our study is to determine the role of age, body mass index (BMI), and fasting plasma C-peptide (FCP) in the classification of diabetes.Methods: This is a descriptive cross-sectional study that included 51 patients aged between 20 and 65 years hospitalized at the Endocrinology Departm...

Introduction: Dopamine agonists, mainly cabergoline and bromocriptine, represent the first-line treatment option in the management of prolactinomas. They allow prolactin normalization and tumor shrinkage. However, a subset of individuals with macroprolactinoma could exhibit a varying degree of resistance to dopamine agonists. The aim of this study was to determine the prevalence of dopamine agonist-resistance in patients with macroprolactinoma and to assess its predictive fact...