Searchable abstracts of presentations at key conferences in endocrinology

ea0002p47 | Genetics | SFE2001

MITOCHONDRIAL GLYCEROL-3-PHOSPHATE-DEHYDROGENASE: ITS TESTIS EXPRESSION AND REGULATION

Chiriaeva N , Weitzel J , Seitz H

The FAD-dependent, mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) is essential for the transport of reducing equivalents derived from glycolysis (or in sperm fructolysis) into the mitochondrial compartment for the synthesis of ATP. It has been shown that multiple (three) promoters of the mGPDH exist so that the expression is regulated in a tissue-restricted manner. Promoter A is expressed in brain, brown adipose tissue and pancreas, promoter B is ubiquitous and promo...

ea0002p97 | Steroids | SFE2001

HUMAN URINARY CORTISOL METABOLITES, SALIVARY AND URINARY FREE CORTISOL AND CORTISONE: CIRCADIAN CHANGES AND EFFECT OF HYDROCORTISONE DOSING

Jerjes W , Wood P , Taylor N

Acute cortisol increase in man, whether from endogenous or exogenous sources, is associated with changes in cortisol:cortisone equilibrium. We have examined these during normal daily circadian rhythms and following treatment with hydrocortisone. Following local ethical committee approval, four adult volunteers (2 male) collected urine samples over 3 hour periods starting from midnight and over hourly periods between 0600 & 0900 to define the morning cortisol peak. They pro...

ea0002p98 | Thyroid | SFE2001

THYROID HORMONES CONCENTRATIONS UNDER PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL STATES IN JAPANESE QUAILS

Rahman Z , Ahmad N , Akram M

Much less information is available on the thyroid hormones at different age groups, laying, non-laying and methimazole (MMI) treated japanese quails. All birds were kept under 14:10 hour light schedule and were provided feed and water adlibitum. Fifteen japanese quailsin each age groups, laying, non-laying and MMI treated were decapitated for collection of plasma. Thyroid hormones (T3 and T4) were estimated using ELISA commercial kits. The results showed that plasma thyroid ho...

ea0002p99 | Thyroid | SFE2001

HORMONAL PROFILES OF BARBRI GOAT DURING PREGNANCY, AT PARTURITION AND POSTPARTUM PERIOD

Rahman Z , Haq I , Ahmad N

Eight healthy pregnant goats, aged 2-4 years, were selected for this study. Blood samples were obtained in tubes containing EDTA at different stages of pregnancy, at parturition and on days 1, 7 and 14 postpartum. Blood from foeti was also collected on days 1 and 7 after their birth. Plasma was separated, frozen at -20 celsius till analysed for thyroid hormones (T3 and T4) using ELISA comercial kits. Thyroxine (T4) concentration was higher during prepartum, decreased significa...

ea0045p5 | Adrenal | BSPED2016

Reviewing the protocol for the standard short synacthen test

Candler T , Daskas N , Crowne EC

Introduction: Assessing cortisol status is a key endocrine investigation, to identify those who need glucocorticoid replacement or emergency sickness cover either due to primary or secondary cortisol deficiency or after long-term/high dose steroid treatment causing Hypothalamic-Pituitary-Adrenal axis (HPAA) suppression. A short synacthen test (SST) measuring cortisol levels after administration of Synthetic ACTH at time zero, 30 and 60 minutes is commonly used. A normal respon...

ea0073s18.3 | Symposium 18: The future of endocrinology Artificial Intelligence (AI) and big data! | ECE2021

AI in endocrine learning

Sampedro-Núñez Miguel

Artificial intelligence (A.I.) impacts patient care but it is also evolving our educational system. Several experts have pointed out the benefits and limitations associated with its use in medicine, however the applications of A.I. in an educational context requires further discussion. The rising popularity of A.I. for medical solutions is evident from the increasing amount of research conducted on this subject, and Endocrine Education should not be an exception. Researchers h...

ea0073aep391 | Endocrine-Related Cancer | ECE2021

A rare cause of postmenopausal hirsutism – granulosa cell tumor of the ovary

N Himamshu Acharya , Selvan Chitra , BK Sujani

Androgen excess in post-menopausal women usually results from ovarian or adrenal pathology. Identifying pathology is significant as many ovarian tumors can be malignant in nature. We report a case of granulosa cell tumor which presented with virilizing signs. A 66-year-old postmenopausal lady presented with temporal hair loss and weight gain. She had to drop out of her church choir as she had a change in her voice. She was concerned about her facial hair growth which was signi...

ea0097020 | Section | BES2023

Hypercalcemia during pregnancy, how to manage it, discussion of a case study

T Carton , N Bahar , B Corvilain

Introduction: Hyperparathyroidism (HPT) during pregnancy is rare but requires a specific approach for its diagnosis HPT is associated with a high incidence of associated maternal, fetal and neonatal complications, including miscarriage (3,5x-fold higher than expected), IUGR, prematurity and pre-eclampsia(1,2,3). The severity of complications is proportional to degree of maternal calcium level.Case report: We report the c...

ea0067gp14 | Poster Presentations | EYES2019

Takotsubo cardiomyopathy: always exclude pheochromocytoma

Gyftaki R , Klogeris N , Dalakoura S , Cherolidi E , Aggelaki M , Bourboulis N , Vryonidou A

Background: Pheochromocytomas are catecholamine-producing neuroendocrine tumors, arising from the adrenal medulla or from paraganglionic chromafin tissue. Their clinical presentation, mainly attributable to the increased catecholamine production and it is highly variable. We herein present a case of a 42-year-old female patient with recurrent episodes of Takotsubo cardiomyopathy due to a pheochromocytoma.Case presentation: The patient presented two years...

ea0037ep333 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Variability of anthropometric, echocardiographic and biochemical indices with comorbidity pathology – essential hypertension and type 2 diabetes

Shalimova A S , Belovol A N , Kochueva M N , Lutsyk V L , Linskaya A V

The mechanisms of development and progression of essential hypertension (EH) and concomitant type 2 diabetes (DM2) still remain not completely studied, so the comprehensive evaluation of the contribution of various indicators to the formation of this comorbidity have scientific interest.The aim of the study was comprehensive assessment of the variability of anthropometric, echocardiographic and biochemical parameters in patients with EH and concomitant D...