Endocrine Abstracts

Introduction: The gluten-free diet is a challenge not only for the patient and their treating physician but also for specialists in the agro-food industry. Gluten-free breads, especially those made from corn, are reputed to be of lower quality than wheat bread. In this context, we conducted a study to test gluten-free cornbread enriched with carob (GFCEC) in terms of flavor, acceptability, and glycemic indexMethods: This is a prospective study involving ...

Introduction: Non-Islet Cell Tumor Hypoglycemia (NICTH) is a rare but serious condition. We report a case of NICTH in a patient with a gastrointestinal stromal tumor.Observation: The patient was a 56-year-old with a history of metastatic gastrointestinal stromal tumor (GIST), diagnosed and operated on in 2016. He received tyrosine kinase inhibitors: Imatinib for 5 years, followed by sunitinib with two courses, and was later declared in palliative care du...

Introduction: The corticosurrenaloma is a rare malignant adrenal tumor with an unfavorable prognosis. The 5-year survival rate at stage IV, defined by the presence of distant secondary locations, does not exceed 28%. We report the case of a patient followed in our department for stage IV corticosurrenaloma and the challenges encountered during her managementCase report : Ms. H, a 42-year-old patient, is under our care for corticosurrenaloma. Her cancer w...

Introduction: Congenital hypogonadotropic hypogonadism (CHH) of hypothalamic or pituitary origin is a rare condition (1 in 5000 births). Clinical manifestations var, depending on the patient’s age and the severity, of the deficiency. CHH is often diagnosed in the context of delayed puberty, without impaired stature, typically, associated with tall stature.Patients and Methods: This is a bicentric study conducted at the Endocrinology Department of He...

Introduction: Congenital hypopituitarism is considered a study model to understand the mechanisms of development and the physiological functioning specific to the pituitary gland. Its exact prevalence is challenging to establish. In this report, we present the experience of the endocrinology department at Hedi Chaker University Hospital in Sfax regarding the diagnosis and management of patients with antehypopituitarism associated with growth hormone deficiency (GHD).<p cla...

Introduction: The pituitary stalk (PS) can be the target of various congenital or acquired pathologies. These conditions are increasingly encountered with the advent and development of magnetic resonance imaging (MRI). Clinically, PS pathology is often revealed by the occurrence of diabetes insipidus. However, other clinical manifestations related to hypothalamo-hypophysial involvement may also be variably associated.Objective: To identify the circumstan...

Introduction: Lymphocytic hypophysitis (LH) is most likely of autoimmune origin, as it is associated with other autoimmune diseases in 20 to 25% of cases, with the most common being lymphocytic thyroiditis. It is common in young women in late pregnancy or postpartum. Diabetes insipidus (DI) occurs in approximately 35% of patients with LH. To link DI to LH, we investigated the clinical, biological, and radiological characteristics of patients with DI.Pati...

Background and Aims: The Rotterdam criteria are the most accepted criteria for the diagnosis of polycystic ovary syndrome (PCOS). The aim of this research work is to study the quality of life of Tunisian and French women with PCOS according to their marital status.Methods: A cross-sectional study involved 172 women with PCOS. Data collection was based on telephone interviews with tunisian patients who were diagnosed with PCOS based on rotterdam criteria ...

Background and Aims: Polycystic ovary syndrome (PCOS) may be the most common endocrine disorder in women of reproductive age. Most research findings suggest that PCOS is associated with eating disorders (ED). The aim of this research work is to study the eating disorders in women with PCOS.Methods: A cross-sectional study involved 172 women, 101 of them are Tunisian and 71 are French. Data collection was based on telephone interviews with Tunisian patien...

Introduction: Couple’s infertility is a major public health problem. Its prevalence is estimated at 15%. In half of the cases, this infertility is of male origin. Different etiologies may be involved, among which genetic abnormalities of the Y chromosome. In this context, we report the cases of two patients with a structural abnormality of the Y chromosome responsible for the abnormalities of spermatogenesisCase Description: The first 26-year-old ca...