Searchable abstracts of presentations at key conferences in endocrinology

ea0014p395 | (1) | ECE2007

Body fat concentration is a poor predictor of bone mineral content in hyperthyroid women

Vulpoi Carmen , Branisteanu Dumitru , Zbranca Eusebie

Hyperthyroidism has significant impact upon both bone turnover and body composition. The present study was designed to investigate whether there is a connection between changes in body composition and bone mineral content at female patients with perturbed thyroid function. Sixty-seven long standing (over 6 months) overt hyperthyroid women had significantly lower bone mineral content as expressed by the Z score measured by quantitative ultrasonography (−0.86+/−0.69 ...

ea0014p504 | (1) | ECE2007

Unusual onset of Graves’ disease – case report

Cristea Cristina , Ciornohuz Adriana , Zbranca Eusebie

Graves’ thyrotoxicosis frequently occurs after delivery through immune rebound mechanism. A 34 years old patient, in postpartum period was referred to rheumatologist for gradually gait impairment. Examination showed only weakness of pelvic girdle muscles which required an extensive differential diagnosis including: neurological diseases and inflammatory/metabolic/toxic myopathies. Routine lab tests were unremarkable except low cholesterol (128 mg/dl) and slightly increase...

ea0014oc2.6 | Bone & calcium metabolism | ECE2007

Sunlight exposure and vitamin D supplementation at the institutionalized elderly – effects on calcium and bone metabolism

Bottermann Peter , Branisteanu Dumitru , Mogos Voichita , Zbranca Eusebie

We investigated calcium and bone metabolism in a group of 123 institutionalized volunteers between 60 and 98 years old, 73 females and 50 males. 25OH-D3 was measured by an indoor RIA technique. 1.25(OH)2D3 was measured by HPLC, serum calcium by photocolorimetry, bone alkaline phosphatase by immunoenzymatic technique, whereas serum PTH and urinary deoxypyridinoline (DPD) were measured by IRMA. Almost all volunteers (92.6%) had low 25OH-D3</...

ea0014p301 | (1) | ECE2007

The influence of smoking upon the incidence of Graves’ disease and severity of Graves’ ophthalmopathy

Zbranca Eusebie , Branisteanu Dumitru , Scurtu Bogdanel , Mogos Voichita

In order to investigate the relationship between Graves’ disease, its associated ophthalmopathy and smoking, we followed retrospectively a group of 270 patients with Graves’ disease (233 females and 37 males). Smoking incidence within this group was compared to that found in a control, thyroid disease-free group of 120 patients. The incidence of smokers was significantly higher in the group with Graves’ disease (145 out of 270, 54%) when compared to the control ...

ea0014p355 | (1) | ECE2007

The relevance of thyroid echography in diagnostic of subclinical autoimmune thyroiditis during pregnancy and postpartum

Carmne Gorduza , Voichita Mogos , Vlad Gorduza Eusebiu , Eusebie Zbranca

Thyroid diseases are more frequent in women. We made a longitudinal study at 112 healthy pregnant women from Iasi county, Romania. The aim of study was to determine incidence and evolution of autoimmune thyroiditis in pregnancy and postpartum. The proceedings of study imposed to verify clinical aspect of thyroid, the volume of thyroid measured echographic, echostructure of thyroid, function of thyroid (TSH, FT4) and autoimmune modification of thyroid (anti-thyroid peroxidase a...

ea0014p372 | (1) | ECE2007

Predictive factors for thyroid function abnormalities in patients with chronic hepatitis C treated with pegylated interferon and ribavirin

Cijevschi Cristina , Mihai Catalina , Zbranca Eusebie , Gogalniceanu Paul

Introduction: Chronic hepatitis C has a high incidence in our country being a major public health issue.Aims and methods: To establish prognostic factors for developing thyroid dysfunction in patients with chronic hepatitis C receiving pegylated interferon and ribavirin therapy. A prospective study of patients with chronic hepatitis C on antiviral therapy was undertaken. 68 patients started on antiviral therapy in the period 1st January 2003 – 1st J...

ea0014p373 | (1) | ECE2007

Aetiology and therapeutic guideines in thyrid dysfunction at the patients with chronic hepatitis C treated with pegylated interferon and ribavirin

Cijevschi Cristina , Mihai Catalina , Zbranca Eusebie , Brumaru Andreea , Gogalniceanu Paul

Introduction: Chronic Hepatitis C is highly prevalent in our country.Management involves combination treatment with pegylated interferon and ribavirin. Thyroid disease in affected patients can be caused by the hepatitis C virus or by the interferon therapy.Aims and method: The study aims to investigate thyroid dysfunction and optimal management strategies for patients with chronic hepatitis C treated with pegylated interferon and r...

ea0014p393 | (1) | ECE2007

The predictive role of body mass and composition upon bone mineral content: differences between premenopausal and postmenopausal women

Branisteanu Dumitru , Piciorea Anca , Zbranca Eusebie , Mogos Voichita

Gravitational stress influences bone mass. Adipose tissue represents a supplementary source of estrogens at postmenopausal women, via aromatization of androgens. We evaluated the importance of weight and fat tissue on bone mass at premenopausal or postmenopausal women in a cross-sectional study upon a group of 138 women between 25 and 77 ys old and with a BMI between 17.1 and 44.3 kg/m2. Fifty six women were menstruating, 15 were perimenopausal and 68 were po...

ea0014p438 | (1) | ECE2007

Cutaneous modifications suggestive for Cushing’s syndrome induced by topical corticoid application

Mogos Simona , Branisteanu Dumitru , Zbranca Anca , Zbranca Eusebie , Mogos Voichita

Topical application of corticosteroids is frequently used in the therapy of various dermatological diseases due to their antiinflammatory and immunsuppressive effects. Systemic pharmacological levels of glucocorticoids lead, on the other hand, to Cushing syndrome, i.e. significant modifications of intermediary metabolism, body composition, bone mass, haematolymphopoietic system and, last but not least, to skin modifications: purple striae, petechiae, infections. We describe a ...

ea0014p521 | (1) | ECE2007

Somatic, body composition and psychological particularities in a group of untreated adult pituitary dwarves

Gotca Ioan , Branisteanu Dumitru , Leustean Letitia , Zbranca Eusebie , Mogos Voichita

Aside its growth promoting effects, growth hormone (GH) displays other actions upon carbohydrate, lipid and protein metabolisms, and possibly also direct central nervous system effects. Fourteen adult pituitary dwarves (mean height of 132.3±8 cm, mean age of 30.7±9.6 y), 5 women and 9 men, never having received rGH therapy, were investigated. Body composition (BC) was assessed by bioelectrical impedance, and bone mineral density (BMD) was evaluated by quantitative ul...