Endocrine Abstracts

Introduction: Liraglutide has shown several benefits in diabetic patients, both in terms of glycemic profile and metabolic control. The objective of our work is to show the effects of liraglutide on the metabolic profile of obese T2D patients.Materials and methods: This is a prospective study involving 31 obese T2D patients followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2018 to December 2022. The data analys...

Introduction: Acromegaly is the set of clinical manifestations induced by chronic exposure to an endogenous excess of growth hormone (GH). Most often, acromegaly is related to GH production by a pituitary adenoma. It may be associated with neuroendocrine tumors of the pancreas as part of multiple endocrine neoplasia type 1 (MEN1). Herein, we described a tumor mimicking a carcinoma of the Ampulla of Vater in a patient with acromegaly.Observation: A 54-yea...

Introduction: Pregnancy in patients with pituitary pathology is a rare and delicate situation. However, risks for the mother and the foetus as well as the consequences of pregnancy on the history of pituitary adenoma require close monitoring.Goals: Illustrate through 5 observations the evolution of pituitary pathology during pregnancy.Observations: 1st patient: 41-year-old followed for somatotropic pituitary macro ...

Introduction: Metabolic disorders caused by acromegaly are responsible for three times the morbidity of the general populationStudy objectives: To analyze the different metabolic complications in acromegalic patients.Materiel and methods: This is a retrospective study of 62 cases of acromegaly followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2005 to December 2022. The data analysis was d...

Introduction: Acromegaly is an unusual disease in adolescence. Its diagnosis and management are a challenge in this population. Here we report 2 rare cases of acromegaly in this age group.Patients and Observations: Observation 1: This is a 17 year old patient admitted for acromegaly on pituitary microadenoma measuring 4*3mm who presents a symptomatology made of an accentuation of the growth rate, thin and long limbs, elongated hands and ...

Introduction: Prolactin adenomas are the most common pituitary adenomas. Although the pituitary increases in size and the prolactinoma increase gradually during normal pregnancy; prolactinomas do not contraindicate pregnancy but require strict monitoring.Goals: To study the impact of pregnancy on the development of prolactin pituitary adenomas.Materials and methods: Retrospective descriptive cohort study conducted in the endocrinol...

Introduction: Cushing’s disease (CD), a hypercorticism caused by an ACTH-secreting pituitary adenoma, was associated with a 5-year survival of only 50%. Although advances in management have significantly reduced mortality, the results of transsphenoidal surgery, the gold standard in the treatment of CD, vary from patient to patient.Objective: The aim of our study is to evaluate the results of transsphenoidal surgery in CD (evolution, complications) ...

Introduction: Hirsutism is defined as excessive pilosity development in women in androgen-dependent areas. It is the main revealing sign of hyperandrogenism. It is a frequent reason for consultation in Endocrinology.Methods: This is a retrospective study of 82 records of patients hospitalized for exploration of hirsutism in the endocrinology department of Farhat Hached Hospital in Sousse, over a period of 20 years from 1997 to 2017.<p class="abstext"...

Introduction: Grave’s orbitopathy (GO) is the main extra-thyroid manifestation of Graves’ disease (GD) and the leading cause of exophthalmia in adults. Its clinical presentation is extremely heterogeneous, ranging from mild ocular discomfort to sight-threatening disease. The aim of our study was to specify the clinical and paraclinical characteristics, as well as the therapeutic modalities of GO.Patients and methods: Descriptive retrospective s...

Introduction: Adrenal myelolipoma is a rare, benign, non-secreting tumor, often found incidentally or in the context of abdominal pain. We report the cases of two patients with adrenal myelolipoma hospitalized at the endocrinology department of diabetology and metabolic diseases of Ibn Rochd University Hospital in Casablanca.Case 1: This is a 30-year-old patient, hospitalized for adrenal mass, revealed by right lower back pain, radiating to the right hyp...