Endocrine Abstracts

Introduction: Menopause correlates endocrine dysfunctions; whether an adrenal incidentaloma represents one of these it is difficult to establish since an age-dependent pattern of incidence has been described. Bone assays are necessary according to years since last menstruation but also if persistent hypercortisolemia is confirmed.Aim: This is a series of cases incidentally found with an adrenal tumor (AT) and osteopenia while evaluation of their menopaus...

Introduction: MEN1 is a rare syndrome characterised by hyperplasia or neoplasm of the parathyroid glands, pituitary, pancreas or duodenum and can associate, less frequently, phaeochromocytoma, thymic or bronchial carcinoids, multiple lipomas, cutaneous angiofibromas and thyroid adenomas.Case report: A 47-year-old woman with MEN1 presenting parathyroid recurrent adenomas, a pituitary prolactin-growth hormone cosecreting macroadenoma, associated with an in...

Given the increasing incidence in psychiatric pathology, adverse reactions of psychotropic medications, especially the metabolic and endocrine side effects, are encountered more frequently in clinical practice. We present the cases of two female patients with psychiatric pathology, in whom the specific treatment was accompanied by significant endocrine adverse reactions, making the tumoural differential diagnosis very difficult. The first case is of a patient aged 61 years, kn...

Introduction: We should consider testing for primary aldosteronism in the presence of hypertension and hypokalaemia, resistant hypertension, onset of hypertension at a young age (<20 year), severe hypertension and whenever considering secondary hypertension.Case report: We presented the case of a 38 years old woman who was admitted in the National Institute of Endocrinology C.I. Parhon Bucharest for the evaluation of high blood pressure. She has high...

Catecholamines can cause hypertension by increasing heart rate and cardiac output or by peripheral vasoconstriction.Aim of study: The value of plasma and urinary metanephrines and normetanephrines does not correlate with blood pressure in pheochromocytomas.Material and methods: The lot of study consist of 35 patients with isolated pheochromocytomas diagnosed between 1985 and 2005 in National Institute of Endocrinology C.I.Parhon Bu...

We presented the case of a 20-year-old woman which has presented for endocrinologic evaluation after right adrenalectomy for pheochromocytoma. From her heredocolateral antecedents, we retain her grandmother and sister of her father with sudden cardiac death at early age. At this presentation, she had normal plasma and urinary MN and NMN. Plasma Cg A and Serotonin are normal and the CT exam showed right adrenalectomy and right renal microlitiasis. Genetic analysis showed mutati...

Background data: Laparoscopic adrenalectomy has became in the last decade “gold standard” for treating of adrenal tumors with diameters smaller than six cm. In addition, one should note than larger tumors or potentially malignant tumors can now also be removed laparoscopically, with virtually no complication.Objective: The authors evaluate the effectiveness of laparoscopic adrenalectomy for a large adrenal tumors.Methods:...

Human adipose tissue provides abundant source of mesenchymal stem cells, which can be easily and safely harvested as compared with human bone marrow.The aim of this study was to differentiate a viable osteoblast and adipocyte cell culture from mesenchymal stem cells, an experimental model to study the interrelation between adipocytes and bone forming cells, osteoblasts.Materials and methods: Subcutaneous adipose tissue liposuction ...

Introduction: Tuberculosis is an insidious disease and may be diagnosed after it afected many organs.Case presentation: We present the case of a 56 years old female, who followed antituberculosis treatment in 2003 for pulmonary tuberculosis and during the treatment developed acute renal failure and for this reason the treatment was stopped. During the evaluations a left kidney tumor was detected. Left nephrectomy was performed in 2003 (HP examination &#1...

Objectives: Endothelial dysfunction has been described as a predictor of cardiovascular complications. Most important cause for early mortality in acromegaly is cardiovascular involvement, cut-off nadir GH <2.5 ng/ml predicting longer survival The aim of our study was to determine the correlations between endothelial dysfunction and GH oversecretion, associated or not with other cardiovascular risk factors.Design and method: Cross-sectional study inc...