Endocrine Abstracts

Introduction: Horner’s syndrome represents a clinical symptom that may result from a variety of lesions both in the central and peripheral nervous system. It is a combination of ipsilateral ptosis, pupillary miosis and anisocoria, enophthalmos and facial anhydrosis induced by disruption of the sympathetic innervation of the eye anywhere along its three-neuron trail. Tumors are the most frequent causes of Horner’s syndrome.Aim: Aim of the study ...

Introduction: Increased production of vasopressin plays a key role in the development of fluid retention and hyponatremia in patients with decompensated heart failure. Antidiuretic hormone deficiency in the course of diabetes insipidus leads to the loss of water, dehydration and hypernatremia. The aim of the study was to present difficulties in successful treatment of hyponatremia in a patient with cardiomyopathy and heart failure, receiving desmopressin because of postoperati...

Introduction: Bilateral adrenalectomy (BA) is rarely applied as a therapeutic procedure. It serves as a life-saving treatment in patients with persistent Cushing’s disease after an ineffective pituitary surgery or in ectopic ACTH production. Other indications for BA are: bilateral adrenocortical adenomas, congenital adrenal hyperplasia and bilateral phaeochromocytoma in patients with hereditary paraganglioma-phaeochromocytoma (PPS/PGL) syndromes. It is also a procedure of...

Introduction: Hyponatremia occurs in 33–69% of women with postpartum pituitary necrosis. The aim of the study was to present a patient in whom recurrent hyponatremia was one of the dominant symptoms of postpartum anterior pituitary hormones deficiency.A case report: 55-year-old woman with a diagnosis of Sheehan syndrome established 19 years after the last labor complicated by massive bleeding due to uterine atonia. The first symptoms of pituitary in...

Introduction: Neurofibromatosis type 1 (NF1; von Recklinghausen’s disease) is an autosomal disorder with the prevalence 1 in 3,000 births. It is caused by mutation of the tumour-suppressor gene encoding neurofibromin. NF1 may affect various organs and patients are at increased risk of developing many neoplasms.Material and methods: We analysed seven cases of patients with NF1 (four females and three males) aged 19–52 who were treated at Endocri...

The transformation of toxic nodular goitre into autoimmune hyperthyroidism with development of thyrotropin receptor antibodies (TSHRAb) as effect of 131I therapy is rarely investigated.The aim of the study is to present cases of patients with toxic nodular goitre who developed autoimmune hyperthyroidism after initial 131I dose, and results of treatment with second 131I dose or thyrostatics.Four pati...

Introduction: Neoplastic lesions in the retroperitoneum may originate from kidneys, ureters, adrenal glands or peripheral nervous, connective, muscle and adipose tissues. Neuroendocrine tumours are exceptionally located in the retroperitoneum.The case study: A woman aged 51, with a tumour of the left adrenal gland found incidentally during an ultrasound examination of the abdominal cavity, which was performed because of dysuria. A CT confir...

Aim: The aim of the study was the evaluation of the TSHRAb level changes and the comparison with thyroid function in patients with Graves’ disease treated with 131I 10 years ago.Material and methods: The study has been conducted in 67 patients (57 women, 10 men) aged 27–72 y (mean 48 years) with Graves’ disease.All patients were treated with 131I due to hyperthyroidism confirmed by fT3, fT4 and ...

Aim: The aim of the study was the evaluation of the relationship between thyroid size and the result of radioactive iodine therapy in patients treated due to Graves’ hyperthyroidism.Material and methods: The study group included 150 subjects (127 M and 23 F), aged from 20 to 78 years (mean 48.33 years) at the moment of 131I therapy.In all patients the thyroid technetium-99m scan and determination of the serum levels...

Introduction: Iodine is critical for thyroid morphology and function. On the one hand, iodine is a factor leading and permitting to origin of disturbances of thyroid follicular cells function, on the other hand, it’s therapeutic agent.Aim: The aim of the study was to evaluate iodine metabolism in different forms of hyperthyroidism and to analyze relationship between metabolism and thyroid size and function.Material and methods...