Endocrine Abstracts

BackgroundPreoperative localisation of parathyroid adenomas may allow more limited neck exploration. Ultrasound is the least expensive imaging technique available. However, correct localisation may be difficult. We have undertaken a study to see whether asking one radiologist (SM) to perform all scans offers a diagnostic advantage.MethodAll patients undergoing surgery for primary hyperparathyroidism since Ju...

Background: Patient Safety Noticed issued by Welsh Government in June 2021 set out multiple action plans to be implemented by Welsh health boards to improve recognition and management of adrenal crisis. Hospitals were advised to review policies to ensure all patients at risk of Adrenal Crisis [(primary/secondary/tertiary adrenal insufficiency (AI)] were identified.Aim: In response, our hospital commenced a quality improv...

Background: Endocrine-metabolic disorders, especially polycystic ovarian syndrome (PCOS) has been linked with increased risk of non-alcoholic fatty liver disease (NAFLD) among reproductive age and implicated hyperandrogenism-driven adipose/hepatic insulin resistance (IR). Gut microbial metabolites such as short chain fatty acids (SCFAs) are crucial modulators of metabolic regulation. However, the impact of SCFAs, in particular, acetate on hyperandrogenism and/...

Background: Cushing’s syndrome is rare (1.8-3.2 cases/million population)1, with Cushing’s disease (CD) accounting >70%. We seek to highlight a rare complication, spinal epidural lipomatosis (SEL), rare cause of spinal compression (prevalence-2.5%2), commonly related to exogenous steroid use with 3 reported cases secondary to CD3,4,5.Case: 36-years old man, background asthma and alcohol excess presented wit...

Background: Carbimazole is a commonly used and effective treatment for hyperthyroidism. Although on the World Health Organisation’s list of essential medicines, it comes with the potentially significant side effect of agranulocytosis. We set out a Quality Improvement Project to improve communication with patients to ensure their understanding through creating a patient information leaflet.Methods: 30 patients receiv...

We report the case of a previously healthy, 40 years old obese male, who was admitted in emergency with complaints of chest pain, shortness of breath and loose stools. His physical examination was relatively unremarkable except for sinus tachycardia and restlessness. He had no history of ischemic heart disease. He was admitted under cardiologists and had various investigations (echocardiogram, stress test and coronary angiogram), all normal. Due to the presentation, thyroid fu...

Hypoglycaemia, a life threatening complication, occurs as part of a wide variety of disease processes. Though a common side effect of diabetes medications, it can be secondary to other factors including, endocrine and, metabolic disorders, severe sepsis, rare malignancies and non-diabetic medications. We present a case series of 3 non-diabetic patients who presented to Princess of Wales, Bridgend with Hypoglycaemic Episodes (HE):1. 23 year old student nu...

Aim: To assess side effects of testosterone (TRT).Introduction: TRT in men with hypogonadism helps improve libido, erectile dysfunction, energy levels and bone density. However the risks/benefits of TRT in terms of ischemic heart disease (IHD), stroke and venous thromboembolism (VTE) is controversial no definitive answers from current evidence. We evaluated the side effects of TRT in patients attending endocrinology outpatient clinic between 2009 to 2019...

Aim: To compare efficacy of different formulations of TRT in treatment of hypogonadismBackground: Different formulations of testosterone are available for treatment of hypogonadism in men. TRT improves libido, sexual function, bone density and general well-being. We analysed data of 106 patients on TRT to compare efficacy of topical and injectable formulations.Methods: It’s a retrospective data analysis of 106 patient receivin...

Milk Alkali syndrome (MAS), a rare cause of hypercalcaemia, is reversible and caused by the ingestion of large amounts of calcium (Ca) and absorbable alkali. We report a case of MAS in a 37 year old female, admitted with Ca of 3.44 (2.15–2.62 nmol/l). Presenting complaints include 6 months history of worsening fatigue, thirst, polyuria, abdominal pain and a complex background of bipolar disorder, fibromyalgia, spina bifida, lumbar spine fusion and extremely limited mobili...