Endocrine Abstracts

Hashimoto’s thyroiditis (HT) is the most frequent thyroid disease in children, in areas of the world with sufficient iodine intake.Aim: To study the clinical features of HT in children at presentation.Material and method: We studied 99 children with HT, 76 (76.8%) girls and 23 (23.2%) boys, with mean chronological age 10.7±2.6 ys (3.2–15.6 ys). The diagnosis of HT was established from the high titers of antithyroid a...

Rathke cleft cysts (RCCs) are non-neoplastic sellar lesions derived from remnants of Rathke’s pouch, and mostly asymptomatic. Symptomatic RCCs occur usually in middle-age, are >1 cm, and cause pituitary hypofunction, diabetes insipidus, hyperprolactinemia or visual impairment. In children, RCCs are rare and usually asymptomatic. However, symptomatic cases may present with growth retardation and diabetes insipidus. We report two children with symptomatic RCC manifestin...

Aim: To estimate the impact of overconsumption of salty and sweet foods on Body Mass Index (BMI) and Blood Pressure (BP) in children.Patients-Methods: We studied 208 children (105 girls), aged 9.2±3.0 yr, 57 (27.4%) of normal weight, 37 (17.8%) overweight and 114 (54.8%) obese. Overconsumption of NaCl was considered >5 g/day and of free sugar >0.5 g/Kg ideal Body Weight/day. BP was measured as appropriate and BMI was estimated in all childre...

Aim: To study the effect of thyroxine treatment on the size of thyroid nodules in children with Hashimoto’s thyroiditisPatients and methods: Twenty-two girls and 6 boys (78.6/21.4%) were followed for 2 years under thyroxine therapy, at mean dose 1.6±0.4 μg/kg per day. Diagnosis of Hashimoto’s thyroiditis was based on the high value of either antithyroid antibodies, ATPO or ATG. Age at presentation was 10.6±2.0 year (6.2–13.6...