Endocrine Abstracts

Introduction: Hypoglycaemia is one of the most important acute complications of diabetes. The fear of hypoglycaemia has a significant effect on the quality of life of patients and their families. It also remains a major barrier to achieve optimal glycaemic control. The GluCare Health care model is centered on the use of Continuous Metabolic Monitoring (CMM) and behavioural change to address metabolic diseases in a continuous manner. The Glucare program aims to provide continuo...

The aim of the study was to assess the role of the estradiol and progesterone relationship during the late luteal phase and the occurrence of fibrocystic breast disease (FBD). The concentration of E2/P was measured in the group of women with FBD as study group and healty control group. All women had regular ovulation cycles. Blood samples for E2, P and prolactin determination were obtained in the morning at 8 am on days 21 and 24 of menstrual cycle. Significant mastalgia and m...

Introduction: The average age for physiological menopause is 50 years. Menopause before the age of 40 is usually defined as premature ovarian failure (POF). POF in adolescents is an extremely rare event and its occurrence raises important questions about the cause-and-effect relationship, which may signal genetic and systemic disorders.Design Case report: The 29-year-old first reported to an endocrinologist for secondary amenorrhea. The anamnesis reveale...

Introduction: The term female pattern hair loss (FPHL) is commonly used synonymously with female androgenetic alopecia. While the the role of androgens and androgen receptor genes is well-defined in male androgenetic alopecia (AGA-M), its role in in the pathogenesis of FPHL is stil uncertain. More diffuse involvement, resulting in an oval-shaped alopecia surrounded by a rim of normal hair density (Luduig’s classification) might be a clinical challenge. The aim of case rep...

Introduction: Some physiological changes in HbA1c during pregnancy should be considered to determine its optimal value for glycemic control. Erythrocytes half-life decreases during pregnancy, which is reflected in a decrease in HbA1c.Aim: The aim of this study is to analyse HbA1c during pregnancy in healthy population of pregnant woman. Matherial and methods: The study included 77 pregnant women in the first trimester registered in Center for endocrinolo...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions with an increase in insulin resistance, moderate, reversible increase in lipid concentration in the blood, and accumulation of fat stores in the mother’s tissues. Lipid metabolism is essential for the development of healthy pregnancy, and fatty acids are a significant source of energy and a key element for membrane synthesis, while cholesterol, in addition ...

Introduction: Acquired modifible long QT syndrome (LQTS) might be caused by hypocortisolism but also drug-induced. Unique genetic association between them is the background of both. The aim of this case report is to present the patient with Addison disease and LQTS not responding on increased dosage of hydrocortison susbstitution therapy.Case report: We report a female patient, 65 years old (1950y.). At the age of 34y. (1984y.) Morbus Addisoni was diagno...

Introduction: Rapid progression of atherosclerosis is classicaly described after e.g. percutaneous transluminal coronary angioplasty or it is defined as an diameter reduction of a preexisting stenosis. However, both initiation and perpetuation mechanisms are rarely descibed in patients on supraphysiological dosages of glucocorticoids (GCs).Case report: We present male patient, 53-year old, after transsphenoidal operation of hypophysis pp. craniopharyngeo...

Objective: The impaired awareness of hypoglycemia (IAH) affects people with type 1 diabetes and is a risk factor for severe hypoglycemia. This study aims to evaluate the association between the impaired awareness of Hypoglycemia by diabetes type 1 and the peripheral neuropathy (PNP).Methods: 276 adults with type 1 diabetes, 135 men and 141 women, were studied from Mai 2015 to January 2016 to the outpatient department of University hospital of Jena. A cro...

Objective: The impaired awareness of hypoglycemia (IAH) affects people with type 1 diabetes and is a risk factor for severe hypoglycemia. This study aims to evaluate the association between the impaired awareness of Hypoglycemia by diabetes type 1 and the peripheral neuropathy (PNP).Methods: 276 adults with type 1 diabetes, 135 men and 141 women, were studied from Mai 2015 to January 2016 to the outpatient department of University hospital of Jena. A cro...