ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2008) 16 P558

Evaluation of metabolic syndrome in patients with diabetes mellitus type 2 using different criteria: National Cholesterol Education Program's Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF)

Ivana Bajkin, Edita Stokic, Tijana Radovanov, Dragana Tomic-Naglic, Dusan Tomic, Milena Munjiza & Veljko Crnobrnja

Clinic of Endocrinology, Diabetes and Metabolic Disorders, Clinical Centre Vojvodina, Novi Sad, Serbia.

The aim of the study was to compare ATPIII and IDF criteria for metabolic syndrome in diabetes mellitus type 2 subjects.

Two hundred and seventy-seven participants were included, 177 women 60.43±8.06 years and 100 men aged 56.35±9.58 years. Group A: metabolic syndrome by ATPIII; group B metabolic syndrome by IDF.

Following laboratory and antropometric measurements were done: total cholesterol, triglycerides, LDL- and HDL cholesterol, fasting plasma glucose, body height, body weight, waist circumference, arterial blood pressure.

We found fewer subjects with metabolic syndrome in group A compared to group B (65% versus 68%). Group B had more women (78%) than group A (71%). In males, it was vice versa (group A 54% versus group B 51%).

Male subjects of group A had statistically significant (P<0.05) smaller waist circumference and mean daily glucose levels compared to male subjects in group B (101±11.54 vs 104±7.64 and 12.89±4.36 vs 14.52±3.94, respectively). Group A had more atherogenic lipid profile (TG 2.76±1.79 in males and 2.59±1.99 females, HDL 1.08±0.13 in males and 1.22±0.3 in females, LDL/HDL 3.71±1.43 in males and 3.27±0.89 in females) compared to group B (TG 2.64±2.01 in males and 2.63±1.96 in females, HDL 1.14±0.33 in males and 1.24±0.31 in females, LDL/HDL 3.42±1.15 in males and 3.23±0.92 in females), but without statistic significance. We did not find statistically significant difference in arterial blood pressure values between two groups (P>0.05).

The use of ATP III and IDF criteria did not show statistically significant difference in detecting metabolic syndrome in all diabetes mellitus type 2 participants (χ2=0.659; P>0.05). There was not any statistically significant difference between women and men (χ2=2.16; P>0.05 and χ2=0.08; P>0.05, respectively).