Endocrine Abstracts

Aim: To investigate the relation of serum lipoprotein (a) (Lp(a)) and other serum lipids with presence of Graves’ Ophthalmopathy (GO). We also analyzed the correlation between serum lipids and GO activity.Methods: A cross-sectional investigation was conducted in consecutive patients with Graves’ Disease (GD) who came under the authors’ observation to receive antithyroid drug. A stratification was aimed at forming two distinct groups of pat...

Objective: To determine the frequency of polycystic ovary syndrome (PCOS) in women with prediabetes compared to control women.Methods: Digital screening and tele-interviews remotely excluded 3218 out of 3465 consecutive women applied for routine check-up. In-person assessments were performed on 247 women, excluding 49. Final analyses included 198 premenopausal women without endocrine disorders (other than prediabetes and PCOS) or conditions affecting gon...

Background: Von Hippel-Lindau disease (VHL) is an autosomal dominant disease, characterized by haemangioblastomas of the retina and CNS, renal cell carcinomas (RCC) and renal cysts, pheochromocytomas, pancreatic neuroendocrine tumors and cysts, and endolymphatic sac tumors. VHL is associated with a germline mutation of the VHL tumor suppressor gene on the short arm of chromosome 3. The type-1 disease is caused by mutations, leading to severe disruption of protein acti...

Recent reports have revealed that leptin’s effects are not restricted to central control of body weight, demonstrating instead that leptin is a pleiotropic hormone with a wide variety of different biological actions. Leptin exhibits undesirable effects in autoimmune diseases, in atherosclerosis, and possibly in several types of cancer, and increases the risk of cardiovascular disease in obese people. Therefore, preparation of reagents capable of abolishing leptin’s a...

We planned to research the effect of the regular exercise of type 2 diabetes mellitus (DM) patients on metabolic control, malondialdehyde (MDA) as the oxidative stress marker and on the quality of life. The study has been carried out 64 patients diagnosed with Type 2 DM for at least 6 months, without any microvascular/macrovascular complication for diabetes, using oral anti-diabetic agent with a HbA1c value of less than 9%. The 31 patients were asked to carry out aerobic exerc...

Aim: Changes in thyroid functions, parenchymal structure and increased frequency of thyroid diseases in inflammatory bowel diseases(IBD) have been described in various studies. In the literature, studies using the data scanning method, most of which belong to the past period, stand out. In this study, we wanted to investigate the relationship between IBD and thyroid diseases in a non-retrospective study. The aim of this study is to systematically check whether there is a relat...

Parathormon treatment for osteoporosis is rarely complicated with hypercalcemia. Vitamin D treatment with high doses frequently can cause asymptomatic intoxication.We present a case with life-threatening hypercalcemia complicated both parathormon and high-dose vitamin D.A 85-year old woman hospitalized for sudden-onset confusion. In history she had coronary-artery by-pass operation and a serebrovascular accedant. She was treated with teriparatide 20 &#95...

Aim: Colonic polyps and thyroid nodules are common diseases and frequency increases with age. In the literature, there is no study investigating the relationship between colonic polyps and thyroid nodules. Therefore, this study was designed to investigate thyroid nodule frequency in patients who have colonic polyps.Material and methods: Sixty-six patients with colonic polyps and 146 patients without colonic polyps enrolled in the study. Age and sex match...

Objective: Establishing good metabolic control is essential to prevent morbidity and mortality in patients with type 2 diabetes (T2DM). This nationwide survey is performed five years after the first national TEMD study, to search for any improvement in attaining glycemic and metabolic targets in Turkish patients with T2DM.Methods: The nationwide, multicenter survey consecutively enrolled patients who were under follow up for at least a year in tertiary c...