Searchable abstracts of presentations at key conferences in endocrinology

ea0077p52 | Metabolism, Obesity and Diabetes | SFEBES2021

How would school children design a poster about diabetes, obesity, health technologies and emotional wellbeing awareness?

Narendran Alisha , Anthony Amarah , Kelly Graham , Xavier Gabriela Da Silva , Shahzad Atif , Arlt Wiebke , Gillett Caroline DT , Kempegowda Punith

Introduction: Knowledge about end-user perceptions is important to ensure educational resources have maximal impact.Objective: To understand school children’s perceptions and ideas about three endocrine topics.Methods: This activity was done as part of Society for Endocrinology public engagement grant. Years 5 and 6 school children (aged 10-11 years) from Nonsuch Primary School in Birmingham were invited to create posters on t...

ea0075r02 | Reproductive Endocrinology | EYES2021

How much do newly graduated healthcare professionals know about PCOS?

Jayaprakash Sindoora , Wicks Saskia , Sheikh Jameela , Zia Nawal , Hebbar Meghnaa , Narendran Alisha , Khalil Halimah , Melson Eka , Gillett Caroline D.T. , Kempegowda Punith

Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine conditions affecting women of reproductive age. Recent studies have shown several long term comorbidities associated with PCOS, thus making it essential that all physicians, regardless of training and specialty, understand and empower women with PCOS to adopt evidence-based behavioral changes. This study set out to establish an understanding of evidence-based lifestyle management of PCOS and the current pract...

ea0049gp186 | Pituitary & endocrine Tumours | ECE2017

24 hour urinary 5-hydroxyindoleacetic acid (5-HIAA) doubling-time (DT) is associated with disease-specific mortality (DSM) and progression-free survival (PFS) in patients with neuroendocrine tumors (NETs)

Tirosh Amit , Nilubol Naris , Patel Dhaval , Kebebew Electron

Background: Biochemical biomarker DT is used clinically for prognosis prediction in several solid malignancies. The aim of the current analysis was to determine whether biomarker DT has any prognostic utility in patients with NETs.Methods: Patients with NETs (n=184) were enrolled in a prospective study with comprehensive biochemical analysis. The current analysis included subjects with increasing 5-HIAA levels in at least two consecutive measure...

ea0073aep175 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Increased anxiety, depression and body dysmorphia in women with polycystic ovary syndrome: Results from blue morpho survey

Sheikh Jameela , Hebbar Meghnaa , Zia Nawal , Wicks Saskia , Jayaprakash Sindoora , Narendran Alisha , Khalil Halimah , Melson Eka , Busby Maureen , Tahrani Abd , Hillman Sarah , Chapman Rachel , Gleeson Helena , Singh Ruchira , Robinson Lynne , Manolopoulos Konstantinos , Gillett Caroline DT , Thangaratinam Shakila , Arlt Wiebke , Kempegowda Punith

BackgroundPolycystic Ovary Syndrome (PCOS) is a common reproductive, endocrine and metabolic disorder. The UK National Institute of Health and Care Excellence (NICE) recommends evaluating emotional wellbeing in women with PCOS. Therefore, we conducted a health service evaluation to assess emotional wellbeing.MethodsWe invited women with PCOS via social media to complete an online survey in September 2020, sup...

ea0075r03 | Reproductive Endocrinology | EYES2021

PCOS SEVa: High prevalence of anxiety, depression and body dysmorphia in people with PCOS suggesting we need to rethink how we screen and manage emotional wellbeing in people with PCOS

Hebbar Meghnaa , Zia Nawal , Sheikh Jameela , Wicks Saskia , Jayaprakash Sindoora , Narendran Alisha , Khalil Halimah , Melson Eka , Busby Maureen , Tahrani Abd A. , Hillman Sarah , Chapman Rachel , Gleeson Helena , Singh Ruchira , Robinson Lynne , Manolopoulos Konstantinos N. , Gillett Caroline D.T. , Thangaratinam Shakila , Arlt Wiebke , Kempegowda Punith

Aim: We evaluated the emotional wellbeing and lifestyle advice received by people with PCOS in comparison to National Institute of Health and Care Excellence (NICE) and international guidelines. Methods: Patients attending fertility clinics at Queen Elizabeth Hospital Birmingham between October 2020-May 2021 and in India between March 2021-May 2021 were invited to complete surveys before and after attending clinic. Pre-clinic survey had questions on demographics, Hospital Anxi...

ea0075r11 | Reproductive Endocrinology | EYES2021

Assessing anxiety, depression and body dysmorphia in young women with and without PCOS: the Blue Morpho Gen Y Survey

Khalil Halimah , Sheikh Jameela , Hebbar Meghnaa , Zia Nawal , Wicks Saskia , Jayaprakash Sindoora , Narendran Alisha , Melson Eka , Busby Maureen , Tahrani Abd A. , Hillman Sarah , Chapman Rachel , Gleeson Helena , Singh Ruchira , Robinson Lynne , Manolopoulo Konstantinos N. , Gillett Caroline D.T. , Thangaratinam Shakila , Arlt Wiebke , Kempegowda Punith

Background: The National Institute of Health and Care Excellence (NICE) recommends evaluating emotional wellbeing in people with polycystic ovary syndrome (PCOS).Objectives: To study differences in various aspects of emotional wellbeing among young women with and without PCOS.Methods: Women aged 18-24 years old at the University of Birmingham were invited to complete an online survey. The survey included validated questionnaires in...

ea0094ns1.3 | Primary Hyperparathyroidism: diagnosis to treatment | SFEBES2023

Parathyroid UK and the Patient Perspective

Fryer Caroline

Parathyroid UK is a national patient organisation committed to improving the quality of life for everyone with parathyroid disorders. We provide information and support to empower our 5,000 members affected by a parathyroid condition to become active in the management of their condition. In Primary Hyperparathyroidism too much parathyroid hormone is produced by one or more enlarged or overactive parathyroid glands, causing hypercalcaemia. This impairs quality of life and incre...

ea0094oc4.1 | Reproductive Endocrinology | SFEBES2023

Unsupervised steroid metabolome cluster analysis to dissect androgen excess and metabolic dysfunction in 488 women with polycystic ovary syndrome – results from the prospective DAISy-PCOS study

Melson Eka , Rocha Thais P. , Veen Roland J. , Abdi Lida , McDonnell Tara , Tandl Veronika , Hawley James M. , Wittemans Laura B. L. , Anthony Amarah V. , Gilligan Lorna C. , Shaheen Fozia , Kempegowda Punith , Gillett Caroline D.T. , Cussen Leanne , Missbrenner Cornelia , Lajeunesse-Trempe Fannie , Gleeson Helena , Rees Aled , Robinson Lynne , Jayasena Channa , Randeva Harpal S. , Dimitriadis Georgios K. , Gomes Larissa G. , J. Sitch Alice , Vradi Eleni , Obermayer-Pietsch Barbara , O'Reilly Michael W. , Taylor Angela E. , Biehl Michael , Arlt Wiebke

Introduction: Polycystic ovary syndrome (PCOS) affects 10% of women and is associated with a 2-3fold risk of type 2 diabetes (T2D), hypertension, fatty liver and cardiovascular disease. Androgen excess has been implicated as a major contributor to metabolic risk in PCOS. We aimed to identify PCOS sub-types with distinct androgen profiles and compare their cardiometabolic risk.Methods: We cross-sectionally studied 488 tre...

ea0094op1.2 | Neuroendocrinology and Pituitary | SFEBES2023

Optimisation of molecular imaging for pituitary tumours using a radioactive phantom

Gillett Daniel , MacFarlane James , Haberbosch Linus , Crawford Rosy , Ballout Safia , Marsden Daniel , Gurnell Mark

Background: Image reconstruction is a key step for the accurate interpretation of positron emission tomography (PET) scans. Nuclear medicine phantoms play a critical role in this process. However, existing phantoms (based on simple geometric shapes) do not reflect the complexity of sellar/parasellar anatomy. We therefore created a novel pituitary phantom and examined the impact of image optimisation on the detection of microadenomas, using 11C-methionine PET s...

ea0077p114 | Reproductive Endocrinology | SFEBES2021

PCOS pearls - gathering perceptions and opinions from lived experiences of people with polycystic ovary syndrome

Lau Gar Mun , Elghobashy Mirna , Busby Maureen , Stacke Kristine , Gleeson Helena , Robinson Lynne , Arlt Wiebke , Lindenmeyer Antje , Gillett Caroline , Kempegowda Punith

Introduction: Existing educational resources for polycystic ovary syndrome (PCOS) have limited inclusion of patient perspectives. We invited people with PCOS to share their lived experiences to understand their perception and opinion on the current standard of care.Methodology: Women aged 18-60 years with PCOS were invited to complete an online survey in April and May 2021. The survey had open questions focused on people’s lived experiences with PCO...