Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 1 of about 16 results

ea0081p214 | Thyroid | ECE2022

Severe refractory active thyroid eye disease: an unmet clinical need in Europe

Tzoulis Ploutarchos , Dosiou Chrysoula

Introduction: Moderate to severe thyroid eye disease (TED) has a significant impact on quality of life. In some cases, TED is resistant to systemic glucocorticoids, the mainstay of treatment since the 1950s, requiring alternative therapies. We describe here a patient with active severe TED who is refractory to various treatments.Case presentation: A 48-year-old non-smoker male, with a long history of psoriasis, vitiligo and atrophic gastritis, presented ...
1 shares

ea0092op-04-02 | Oral Session 4: Young Investigators / Clinical and Translational | ETA2023

Teprotumumab-Related adverse events in thyroid eye disease: a multi-center real world study

Shah Shreya , Amarikwa Linus , Sears Connie , Ugradar Shoaib , Clauss Kevin , Rajjoub Raneem , Kang Julia , Tamhankar Madhura , Briceno Cesar , Harrison Andrew , Dosiou Chrysoula , Cockerham Kimberly , Wester Sara , Douglas Raymond , Kossler Andrea

Objectives: The insulin-like growth factor I receptor (IGF-1R) plays a significant role in the pathology of thyroid eye disease (TED), an autoimmune disorder characterized by orbital inflammation. Teprotumumab, a human monoclonal antibody targeting IGF-1R, has demonstrated efficacy in treating moderate-to-severe TED. A significant proportion of patients experienced adverse events (AEs), with 74% and 85% reporting an AE and 12% and 5% reporting serious AEs in Phase 2 and 3 tria...
6 shares

ea0090ep25 | Adrenal and Cardiovascular Endocrinology | ECE2023

Endocannabinoids in patients with adrenal incidentalomas. A new prognostic biomarker?

Mytareli Chrysoula , Athanasouli Fani , Karampela Athina , Papalexis Petros , Siampanopoulou Vasiliki , Lafioniatis Alexandros , Mantzourani Marina , Angelousi Anna

Background: The majority of adrenal incidentalomas (AIs) are benign non-functioning adrenocortical adenomas (NFAIs), yet not clinically silent. Possible autonomous cortisol secretion (PACS) can also be diagnosed in up to 50% of patients. Endocannabinoids (ECs) have recently been studied regarding their role in the hypothalamo-pituitary-adrenocortical (HPA) axis; however, data are scarce in humans.Aim: We aimed to assess hair EC [anandamide (AEA) and 2-ar...
0 shares

ea0073aep49 | Adrenal and Cardiovascular Endocrinology | ECE2021

Hair cortisol levels in patients with adrenal incidentalomas compared to healthy controls

Athanasouli Fani , Mytareli Chrysoula , Andreadaki Evangelia , Petychaki Foteini , Savelli Akrivi , Asonitis Nikos , Anna Angelousi

BackgroundAdrenal incidentalomas (AI) are present in 3–10% of the general population. Up to 20% of them may have autonomous cortisol secretion (ACS). However, subclinical hypercortisolism isn’t clearly defined. The 1mg dexamethasone suppression test (ODST) is the most widely accepted for the screening of these patients. Recent data suggest that hair cortisol should be considered as a routine test for the screening of Cushing syndrome.<p cla...
0 shares

ea0090p590 | Calcium and Bone | ECE2023

Post-thyroidectomy development of posterior reversible encephalopathy syndrome (PRES) due to over-replacement of hypocalcemia

Papalou Olga , Katechakis Nikolaos , Koukoula Chrysoula , Beka Aikaterini , Baikousi Dimitra , Gkoufa Kyriaki , Mandrapylia Angeliki , Stratigou Theodora , Vassiliadi Dimitra , Tsagarakis Stylianos

A 61-year-old woman was admitted to the Emergency Department with generalized seizures. She reported general malaise, anorexia, headache and multiple episodes of vomiting that started about 12 h before admission. She had a history of recent thyroidectomy, and she was on oral calcium carbonate (3 gr/day) and alpha calcidol (3 mg/day). Non-contrast head CT scan was negative for major findings. Laboratory work up revealed hypercalcemia (corrected calcium 14,4 mg/dl), renal impair...
0 shares

ea0090ep173 | Calcium and Bone | ECE2023

The effect of Immune Checkpoint Inhibitors (ICIs) in Bone Metabolism: A case series analysis

Siampanopoulou Vasiliki , Angelousi Anna , Karampela Athina , Papalexis Petros , Lafioniatis Alexandros , Mytareli Chrysoula , Ziogas Dimitrios , Gogas Helen , Kassi Evanthia

Background: Immune checkpoint inhibitors (ICIs) constitutes a novel treatment for patients with melanoma. Endocrine-related adverse effects are now a distinctive clinical entity of ICIs, with hypophysitis and thyroiditis being the most common. Recent consensus doesn’t suggest routinely screening of bone mass indexes in patients on ICIs since data in the literature are scarce.Methods: Data regarding bone disease were retrospectively analysed in 118 p...
2 shares

ea0049ep1126 | Female Reproduction | ECE2017

Graduated response to pulsatile GnRH therapy in hypothalamic amenorrhea

Germain Natacha , Fauconnier Anais , Klein Jean-Philippe , Wargny Amelie , Khalfallah Yadh , Papastathi-Boureau Chrysoula , Estour Bruno , Galusca Bogdan

Introduction: Pulsatile GnRH therapy is currently used to restore LH pulse and induce physiological ovulation, with effectiveness demonstrated in all types of hypothalamic amenorrhea (HA). Anorexia nervosa (AN) is characterized by self-starvation-induced undernutrition leading to functional hypothalamic amenorrhea (HA). Weight recovery does not always restore menses despite no apparent clinical and biological undernutrition residual signs. Only few specific studies on persiste...
0 shares

ea0014p89 | (1) | ECE2007

Lipoprotein Lp(a) in patients with systemic lupus erythematosus. Relationship with disease activity and anticardiolipin antibodies

Athanassiou Panagiotis , Kostoglou-Athanassiou Ifigenia , Papadopoulou Despina , Galanaki Chrysoula , Kalogirou Thomais , Kordalis Athanasios , Antoniadis Christodoulos , Kaldrymidis Philippos

Systemic lupus erythematosus (SLE) is a multisystem multifactorial autoimmune disorder. The survival of SLE patients has been improved by the administration of immunomodulatory therapy. Patients, however, are affected by late onset complications of the disease such as atherosclerosis. Lipoprotein Lp(a) is a known risk factor for the development of atherosclerosis.The aim was to study Lp(a) levels and their relationship with disease activity in SLE patien...
0 shares

ea0014p90 | (1) | ECE2007

Lipoprotein Lp(a) in patients with rheumatoid arthritis and its relationship with disease activity

Athanassiou Panagiotis , Kostoglou-Athanassiou Ifigenia , Papadopoulou Despina , Galanaki Chrysoula , Kalogirou Thomais , Kordalis Athanasios , Antoniadis Christodoulos , Kaldrymidis Philippos

Epidemiological studies indicate that rheumatoid arthritis (RA) patients have increased mortality. Cardiovascular disease seems to be one of the major causes of death in patients with RA. Lipoprotein disorders are observed in patients with systemic autoimmune disorders as well as in patients with RA. Lipoprotein Lp(a) is an independent risk factor for the development of cardiovascular disease.The aim of the study was estimate lipoprotein Lp(a) levels and...
0 shares

ea0099ep258 | Adrenal and Cardiovascular Endocrinology | ECE2024

Psychometric parameters and quality of life in patients with adrenal tumours

Charikleia Tasouli Elisavet , Mytareli Chrysoula , Andreadaki Evangelia , Thanasoula Foteini , Siampanopoulou Vasiliki , Karabela Athina , Papalexis Petros , Lafioniatis Alexandros , Angelousi Anna

Introduction: Neuropsychiatric disorders are common and well-studied in patients with overt hypercortisolism. However, data regarding patients with adrenal incidentalomas (AIs) are limited. The aim of our study is to assess the psychometric and quality of life status in individuals with benign adrenal tumours.Methods: Eighty-two patients diagnosed with AIs, encompassing 53 females and 29 males, with a total mean age of 64 years and 52controls (without AI...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more