Endocrine Abstracts

Objective: Fetal hyperinsulinemia correlated with large birth weight and impaired glucose tolerance test and obesity in second decades of life. In study we compared the correlation between Fetal Insulin production (as estimated by amniotic fluid (AF) C-peptide concentration) and AF Insulin with macrosomia (as estimated by neonatal birth weight >4000 gr).Methods: Thirty eight neonates was studied: Ten infants were macrosomia and twenty eight was norma...

Cellular sensitivity to circulating glucocorticoids is critical and is principally determined by the level of glucocorticoid receptor (GR). GR expression is most potently regulated by glucocorticoids themselves, although the mechanism is unknown. The rat GR gene encodes at least eleven alternate and untranslated exons 1, eight of which lie in a 3kb CpG island close to exon 2. We have recently shown that individual exons 1 are subject to tissue specific expression and regulatio...

Different studies have been done in the field of effect of magnetic field exposure on the biological organs. The aim of this study was to investigate the effects of static magnetic field (SMF) exposure on the secretion of hypothalamic-pituitary-gonadal axis in the male rats during short and long time exposed to SMFs (50 Hz).Methods: Experiments have been done in four protocols. Each protocol included four groups (Wistar male rats, same range of age and w...

Introduction: Overweight and obesity are being emerged as one of the most prevalent nutritional problems among children in developed and developing countries. To decrease the rate of them there is need to know more about effective factors.Objective: This study aimed to determine association between energy and nutrients intake with overweight / obesity in male and female school children of Tehran.Methods: A sample of 761 school stud...

Height and weight measurement is an important data source in affairs related to growth and development, puberty and nutritional status of children and adolescents. In clinical setting NCHS charts are used in Iran. Although there were significant differences among provinces, between urban and rural children and all the percentiles of growth charts from the data of national health survey in Tehran, in 1990-1992, were substantially below but similar to those of the NCHS charts. I...

Background: Diabetes is considered as one of the most common chronic diseases. Since diabetes complications can lead to falls in the elderly and according to the fact that the risks associated with falling are multifactorial, the aim of this study was to explore the association between activity of daily living (ADL) and falling in older people with diabetes admitted to the selected hospitals of tehran university of medical sciences.Methods: A case–c...

Introduction: FNA (fine needle aspiration) is a highly sensitive and specific procedure in evaluating of thyroid nodules. There are several options for processing the FNA specimen such as direct smears, cell block preparations (CBP) and liquid base preparations (LBP); the latter has become more popular due to its easy transport, fast protocol and also the possibility to study different parts of the specimen. In this study, we compare the results of cell block and liquid base p...

Introduction: Acromegaly is a clinical condition results from GH hypersecretion which is usually elaborated by a somatotroph adenoma. Mass effect of adenoma and resulting hormonal changes impair fertility during pregnancy, estrogen-mediated pituitary enlargement along with enhanced pituitary vascularity is a true risk for tumor hemorrhage.Case presentation: The 28-years-old patient first visited by the endocrinologist in 2004 for secondary amenorrhea and...

Introduction: Rheumatoid arthritis, the most common inflammatory arthritis, is commonly seen with thyroid hormone autoantibodies and thyroid dysfunction.In this survey we evaluate the thyroid function and the prevalence of thyroid autoantibody, autoimmune thyroiditis and other forms of thyroid dysfunction to determine whether these patients should be screened for thyroid disease.Material and methods: Our study included 224 rheumatoid arthritis patients (...

Background: Hyponatremia is the most prevalent electrolyte disorder in hospitalized adult medical patients and is associated with a significant healthcare resource burden. However, evidence remains scarce whether hyponatremia is a marker of disease severity or whether it has an independent effect on clinical outcomes.Methods: In this nationwide cohort study, we analyzed medical inpatients with hyponatremia diagnosed between January 2009 through December ...