Endocrine Abstracts

Aim: The main aim of this study was to examine the association of glucose and sodium level with diagnosis and disease outcome of critically ill patients.Patients and Methods: The glucose and sodium concentration of 283 patients admitted in critical condition to the Intensive Care Unit of the Department of Internal Medicine in a period from 1 November 2015 to 28 February 2017 were reviewed.Results: Most common diagnoses in criticall...

Background and aims: Diabetic ketoacidosis is acute complication of diabetes mellitus. Hyperglycemia is one of the diagnostic features of diabetic ketoacidosis. Electrolyte disturbances are common as well. Aim of this study is to examine whether there is a difference in serum glucose, sodium and potassium concentrations with respect to age, gender and severity of diabetic ketoacidosis.Materials and Methods: Medical records from 1 January 2017 to 31 Decem...

Aim: The aim of the study was to determine the most common precipitating factors and symptoms of diabetic ketoacidosis and whether there is a difference in regard to age, gender and severity of diabetic ketoacidosis.Patients and Methods: Medical records from 1 January 2017 to 31 December 2019 were reviewed and patients with the diagnosis of diabetic ketoacidosis were selected.Results: The study included 52 patients. The median age ...

Objective: Cardiovascular diseases are the most common comorbidities in acromegaly. Potential parameters in pathology of cardiovascular comorbidities are changes in levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) as well as body composition parameters.Purpose: The aim of this study was to examine morphological and functional parameters of the cardiovascular system by echocardiography and to assess its relationship with disease acti...

Introduction: The term female pattern hair loss (FPHL) is commonly used synonymously with female androgenetic alopecia. While the the role of androgens and androgen receptor genes is well-defined in male androgenetic alopecia (AGA-M), its role in in the pathogenesis of FPHL is stil uncertain. More diffuse involvement, resulting in an oval-shaped alopecia surrounded by a rim of normal hair density (Luduig’s classification) might be a clinical challenge. The aim of case rep...

Introduction: Acquired modifible long QT syndrome (LQTS) might be caused by hypocortisolism but also drug-induced. Unique genetic association between them is the background of both. The aim of this case report is to present the patient with Addison disease and LQTS not responding on increased dosage of hydrocortison susbstitution therapy.Case report: We report a female patient, 65 years old (1950y.). At the age of 34y. (1984y.) Morbus Addisoni was diagno...

Introduction: Rapid progression of atherosclerosis is classicaly described after e.g. percutaneous transluminal coronary angioplasty or it is defined as an diameter reduction of a preexisting stenosis. However, both initiation and perpetuation mechanisms are rarely descibed in patients on supraphysiological dosages of glucocorticoids (GCs).Case report: We present male patient, 53-year old, after transsphenoidal operation of hypophysis pp. craniopharyngeo...

Background: In the 2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular diseases, only retinopathy appears as a target organ damage as a parameter for stratification patients into very high-risk group. The aim of study was to check the strength of association between DN and isolated DR groups with cardiovascular complications.Methods: Chronic kidney disease (CKD) was defined by eGFR ≤ 59 ml/min/1.73 m2 and proteinuria (P...

Introduction: The fact that up to 33% with type 2 diabetes develop hypogonadotropic hypogonadisms (HH), are still not catching enough attention. More futher ’’the 5-year mortality of somebody who has got diabetes, who has had a myocardial infarction is actually lower than the diabetic patient who has developed a diabetic foot ulcer, which is around 48%’’.Case description: We describe male patient, 47 y. (on 2016y), newly diagnosed...

IntroductionInfertility associated with hypergonadotropism is usually an unpromising condition related to acheiving fertilization. We describe the patient presented as oligoasthenoteratozoospermia (OAT syndrome), with laboratory primary hypergonadotropic hypogonadism but normal male fenotype, including typical male hair dustribution.Case descriptionmale, born 41 year ago, presented when he was 29 year old, as...